http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Yukai Tao (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
An Effective SVM Ensemble Algorithm Based on Different Thresholds of PCA
Yukai Yao,Bo Wang,Qingjun Yang,Dongsheng Ji,Tao Ma,Xiaoyun Chen 보안공학연구지원센터 2016 International Journal of Database Theory and Appli Vol.9 No.2
This paper proposes an effective ensemble classifier, named PCAenSVM, which consists of ten weak Support Vector Machine classifiers based on different Principal Component Analysis thresholds. Those ten base Support Vector Machine classifiers are made up to fulfill classification tasks using Majority Voting strategy. Experiments are made on four UCI data sets and a data set from the Uppsala University to evaluate the performances of PCAenSVM. The results of PCAenSVM are compared with that of LibSVM and EnsembleSVM. Experimental results show that PCAenSVM has better classification accuracy than other two algorithms. Moreover, PCAenSVM has the same confidence level with the LibSVM, and its confidences of accuracy and sensitivity on those five data sets outperform that of the EnsembleSVM.
-
Fanyun Kong,Yukai Tao,Dongchen Yuan,Ning Zhang,Qi Li,Tong Yu,Xiaoying Yang,Delong Kong,Xiaohui Ding,Xiangye Liu,Hongjuan You,Kuiyang Zheng,Renxian Tang 대한암학회 2021 Cancer Research and Treatment Vol.53 No.2
Purpose C5α receptor 1 (C5ΑR1) is associated with the development of various human cancers. However, whether it is involved in the development of hepatitis B virus (HBV)–related hepatocellular carcinoma (HCC) is poorly understood. We explored the expression, biological role, and associated mechanisms of C5AR1 in HBV-related hepatoma cells. Materials and Methods The expression of C5ΑR1 mediated by HBV and HBV core protein (HBc) was detected in hepatoma cells. The function of nuclear factor кB (NF-κB) pathway in HBc-induced C5AR1 expression was assessed. The roles of C5ΑR1 in the activation of intracellular signal pathways, the upregulation of inflammatory cytokines, and the growth and migration of hepatoma cells mediated by HBc, were investigated. The effect of C5α in the development of HCC mediated by C5AR1 was also measured. Results C5ΑR1 expression was increased in HBV-positive hepatoma cells. Dependent on HBc, HBV enhanced the expression of C5ΑR1 at the mRNA and protein levels. Besides, HBc could promote C5ΑR1 expression via the NF-κB pathway. Based on the C5ΑR1, HBc facilitated the activation of JNK and ERK pathways and the expression and secretion of interleukin-6 in hepatoma cells. Furthermore, C5ΑR1 was responsible for enhancing the growth and migration of hepatoma cells mediated by HBc. Except these, C5α could promote the malignant development of HBc-positive HCC via C5AR1. Conclusion We provide new insight into the mechanisms of hepatocarcinogenesis mediated by HBc. C5ΑR1 has a significant role in the functional abnormality of hepatoma cells mediated by HBc, and might be utilized as a potential therapeutic target for HBV-related HCC.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
