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Hongli Gong,Boyan Wang,Yi Shi,Yong Shi,Xiyan Xiao,Pengyu Cao,Lei Tao,Yuezhu Wang,Liang Zhou 한국미생물학회 2017 The journal of microbiology Vol.55 No.8
The pharynx is an important site of microbiota colonization, but the bacterial populations at this site have been relatively unexplored by culture-independent approaches. The aim of this study was to characterize the microbiota structure of the pharynx. Pyrosequencing of 16S rRNA gene libraries was used to characterize the pharyngeal microbiota using swab samples from 68 subjects with laryngeal cancer and 28 subjects with vocal cord polyps. Overall, the major phylum was Firmicutes, with Streptococcus as the predominant genus in the pharyngeal communities. Nine core operational taxonomic units detected from Streptococcus, Fusobacterium, Prevotella, Granulicatella, and Veillonella accounted for 21.3% of the total sequences detected. However, there was no difference in bacterial communities in the pharynx from patients with laryngeal cancer and vocal cord polyps. The relative abundance of Firmicutes was inversely correlated with Fusobacteria, Proteobacteria, Actinobacteria, and Bacteroidetes. The correlation was evident at the genus level, and the relative abundance of Streptococcus was inversely associated with Fusobacterium, Leptotrichia, Neisseria, Actinomyces, and Prevotella. This study presented a profile for the overall structure of the microbiota in pharyngeal swab samples. Inverse correlations were found between Streptococcus and other bacterial communities, suggesting that potential antagonism may exist among pharyngeal microbiota.
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Renlai Zhou,Jiancun Ren,Shuli Lou,Youlun Ju,Yuezhu Wang 한국광학회 2015 Current Optics and Photonics Vol.19 No.1
Up to ~520 μJ broadband mid-infrared (IR) supercontinuum (SC) generation in telecommunicationmultimode fiber (MMF) directly pumped by a 2.054 μm nanosecond Q-switched Tm,Ho:YVO4 laser isdemonstrated. An average output power of 3.64 W is obtained in the band of ~1900 to ~2600 nm, andthe corresponding optic-to-optic conversion efficiency is 67% by considering the coupling efficiency. Thespectrum has extremely high flatness with negligible intensity variation (<2%) in the wavelength intervalof ~2070 to ~2475 nm. The SC long-wavelength edge is limited by the silicon glass material loss, andby optimizing the MMF length, the SC spectrum could extend out to ∼2.6 μm. The output SC pulseshapes are measured at different output powers, and no splits are found. The SC laser beam is nearlydiffraction limited with an M2 =1.15 in 2.1 μm measured by the traveling knife-edge method, and thelaser beam spot is monitored by an infrared vidicon camera
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