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RISS 인기검색어
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- 저자 : Yu Shimizu (검색결과 6 건)
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Light flavon signals at electron-photon colliders
Muramatsu, Yu,Nomura, Takaaki,Shimizu, Yusuke,Yokoya, Hiroshi American Physical Society 2018 Physical Review D Vol.97 No.1
<P>Flavor symmetries are useful to realize fermion flavor structures in the standard model (SM). In particular, the discrete A(4) symmetry is used to realize lepton flavor structures, and some scalars-called flavons-are introduced to break this symmetry. In many models, flavons are assumed to be much heavier than the electroweak scale. However, our previous work showed that a flavon mass around 100 GeV is allowed by experimental constraints in the A(4) symmetric model with a residual Z(3) symmetry. In this paper, we discuss collider searches for such a light flavon phi(T). We find that electron-photon collisions at the International Linear Collider have advantages for searching for these signals. In electron-photon collisions, flavons are produced as e(-)gamma -> l(phi T)(-) and decay into two charged leptons. Then, we analyze signals of the flavor-conserving final state tau(+)tau(-)e(-) and the flavor-violating final states tau(+)mu(-)mu(-) and mu(+)tau(-)tau(-) by carrying out numerical simulations. For the former final state, SM background can be strongly suppressed by imposing cuts on the invariant masses of final-state leptons. For the latter final states, SM background is extremely small, because in the SM there are no such flavor-violating final states. We then find that sufficient discovery significance can be obtained, even if flavons are heavier than the lower limits from flavor physics.</P>
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Takashi Sono,Shunsuke Fujibayashi,Yu Shimizu,Bungo Otsuki,Shimei Tanida,Shuichi Matsuda 대한척추외과학회 2019 Asian Spine Journal Vol.13 No.5
Study Design: Retrospective cohort study. Purpose: The aim of our study is to evaluate the extent of posterior spinal dural shift following spinous process splitting multi-level intervertebral lumbar laminectomies, and determine the relationship between posterior spinal dural shift and preoperative parameters. Overview of Literature: There are no existing studies on the posterior spinal dural shift after spinous process-splitting multi-leveled lumbar laminectomies. Methods: We examined 37 patients who underwent spinous process-splitting laminectomies in at least two intervertebral levels, including at the L5/S level. We defined the distance between the vertebral bodies and the anterior edge of the dural sac in the magnetic resonance images at the L5 vertebral level as the anterior dural space (ADS) and detected the difference (d-ADS) between preoperative ADS (pre-ADS) and postoperative ADS (post-ADS). We assessed the relationship between ADS or d-ADS, and preoperative parameters, including age, sex, lumbar lordosis, focal lordosis (FL), and number of decompression levels. Results: Post-ADS was significantly greater than pre-ADS (p<0.001). Pre-ADS was significantly correlated with FL (p=0.44, p<0.01) and also with post-ADS (p=0.43, p<0.01). d-ADS was negatively correlated with pre-ADS (p=−0.37, p<0.05). A single regression analysis revealed that the relationship between d-ADS and pre-ADS was described as d-ADS=3.67−0.46×pre-ADS. In one of three patients whose d-ADS was above the range of two standard errors, reoperation was performed because of impingement of the nerve root caused by the excessive posterior dural shift. Conclusions: Posterior dural shifts occur after spinous process-splitting multi-level lumbar laminectomies, including at the L5/S level. FL and pre-ADS are good predictive factors for posterior dural shift. Excessive posterior dural shift may lead to stretching and impingement of nerve roots and thus require attention.
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Nao Yamaoka,Kazunori Shimizu,Yu Imaizumi,Yohei Okada,Hiroyuki Honda 한국바이오칩학회 2019 BioChip Journal Vol.13 No.2
Degeneration of motor neurons and skeletal muscles or the collapse of neuromuscular junctions (NMJs) causes progressive motility disturbances in many neuromuscular diseases. Although various microdevices for the co-culture of skeletal muscle myotubes and motor neurons have been developed to investigate neuromuscular diseases in vitro, it remains difficult to isolate single myotubes and motor neurons from the device for single-cell analyses, such as gene expression analysis. Here, we developed open chamber-coculture microdevices that contain cell culture chambers with narrow widths. Given the small chamber width (0.2 mm), the device significantly prevented the overlap among myotubes within the chamber. The percentage of non-overlapping was 95.6 ± 7.7% for the 0.2-mmwidth chamber and 11.8 ± 6.4% for the 7-mm-width chamber as a control. In addition, the device with the 0.2-mm chamber promoted myotube maturation, as indicated by the longer widths and lengths of the myotubes relative to those in the control chamber. Single C2C12 myotubes and human induced pluripotent stem cell (hiPSC)-derived motor neurons were successfully collected from the device with the 0.2-mm chamber using a micromanipulator equipped with a glass capillary. Furthermore, myotubes and hiPSC-derived motor neurons were co-cultured in the device with the 0.2- mm chamber, and the formation of NMJs were observed. Thus, the developed device is a useful tool for performing single-cell analysis for studying neuromuscular diseases in vitro.
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Interventional management for postoperative arterial bleeding in gastrointestinal surgery
Yozo Sato,Kiyoshi Matsueda,Marie Osawa,Yoshitaka Inaba,Yu Takahashi,Yosuke Inoue,Atsushi Oba,Yosuke Fukunaga,Yasuhiro Shimizu 소화기인터벤션의학회 2022 Gastrointestinal Intervention Vol.11 No.4
Postoperative arterial bleeding after gastrointestinal surgery is a potentially fatal complication. Transcatheter arterial embolization is considered the first-line treatment because of efficacy and less invasiveness despite the risk of organ infarction. With the recent advances in endovascular devices, stent-graft placement, which can preserve arterial flow, has been an alternative treatment option in patients with extrahepatic artery hemorrhage. Moreover, clinical outcomes of stent-graft placement for pseudoaneurysms in relative long term have been reported recently. Herein, we review the techniques and clinical outcomes for interventional management for postoperative arterial bleeding.
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Interventional management for postoperative arterial bleeding in gastrointestinal surgery
Yozo Sato,Kiyoshi Matsueda,Marie Osawa,Yoshitaka Inaba,Yu Takahashi,Yosuke Inoue,Atsushi Oba,Yosuke Fukunaga,Yasuhiro Shimizu 소화기인터벤션의학회 2022 International journal of gastrointestinal interven Vol.11 No.4
Postoperative arterial bleeding after gastrointestinal surgery is a potentially fatal complication. Transcatheter arterial embolization is considered the first-line treatment because of efficacy and less invasiveness despite the risk of organ infarction. With the recent advances in endovascular devices, stent-graft placement, which can preserve arterial flow, has been an alternative treatment option in patients with extrahepatic artery hemorrhage. Moreover, clinical outcomes of stent-graft placement for pseudoaneurysms in relative long term have been reported recently. Herein, we review the techniques and clinical outcomes for interventional management for postoperative arterial bleeding.
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