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Jae-Min Kim(Jae-Min Kim),Hee-Ju Kang(Hee-Ju Kang),Ju-Wan Kim(Ju-Wan Kim),Wonsuk Choi(Wonsuk Choi),Sung-Wan Kim(Sung-Wan Kim),Jung-Chul Kim(Jung-Chul Kim),Byung Jo Chun(Byung Jo Chun),Youngkeun Ahn(You 대한정신약물학회 2023 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.21 No.2
Objective: We investigated effects of serum serotonin and interleukin 18 levels on suicidal ideation (SI) at acute and chronic phases of acute coronary syndrome (ACS). Methods: Recent-onset 969 ACS patients were evaluated for serum serotonin and interleukin 18 levels; and SI by the “suicidal thoughts” item of the Montgomery–Åsberg Depression Rating Scale. After 1-year, 711 patients were re-evaluated for SI. Logistic regression models were used adjustment for potential covariates. Results: Associations between serum interleukin 18 and SI at both phases were significant only in the lower serotonin group. Conclusion: By evaluating serum serotonin and interleukin 18 levels, the clinical prediction of SI of ACS may be improved.