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        Glucose-lowering Effect of Powder Formulation of African Black Tea Extract in $KK-A^y/TaJcl$ Diabetic Mouse

        Shoji, Yoko,Nakashima, Hideki The Pharmaceutical Society of Korea 2006 Archives of Pharmacal Research Vol.29 No.9

        We observed the suppressive effect of a powder formulation of African black tea extract prepared from the leaves of Camellia sinensis on type 2 non-insulin dependent diabetic mice, $KK-A^y/TaJcl$. Black tea extract significantly showed suppressive effect of the elevation of blood glucose on oral glucose tolerance test of 8 week-old $KK-A^y/TaJcl$ mice (p<0.05). Long-term treatment with black tea extract showed significant suppression of post-prandial blood glucose and obesity (p<0.05). The weight of the intestine of mice treated with black tea extract was significantly reduced (p<0.05). From these results, African black tea used in this study showed a suppressive effect on the elevation of blood glucose during food intake and the body weight.

      • KCI등재

        Glucose-lowering Effect of Powder Formulation of African Black Tea Extract in KK-Ay/TaJcl Diabetic Mouse

        Yoko Shoji,Hideki Nakashima 대한약학회 2006 Archives of Pharmacal Research Vol.29 No.9

        We observed the suppressive effect of a powder formulation of African black tea extract prepared from the leaves of Camellia sinensis on type 2 non-insulin dependent diabetic mice, KKA y/TaJcl. Black tea extract significantly showed suppressive effect of the elevation of blood glucose on oral glucose tolerance test of 8 week-old KK-Ay/TaJcl mice (P<0.05). Long-term treatment with black tea extract showed significant suppression of post-prandial blood glucose and obesity (P<0.05). The weight of the intestine of mice treated with black tea extract was significantly reduced (P<0.05). From these results, African black tea used in this study showed a suppressive effect on the elevation of blood glucose during food intake and the body weight.

      • KCI등재

        Effects of Body Pillow Use on Sleeping Posture and Sleep Architecture in Healthy Young Adults

        Park Insung,Suzuki Chihiro,Suzuki Yoko,Kawana Fusae,Yajima Katsuhiko,Fukusumi Shoji,Kokubo Toshio,Tokuyama Kumpei,Yanagisawa Masashi,Satoh Makoto 대한수면학회 2021 sleep medicine research Vol.12 No.1

        Background and Objective Patients with position-dependent obstructive sleep apnea have a > 2-fold higher apnea-hypopnea index when sleeping in a supine position compared with a non-supine position. We investigated the effect of body pillow use on sleeping body position and sleep architecture in healthy young adults. Methods In experiment 1, we evaluated the body pressure distribution with or without body pillow use in 8 healthy young adults [age, 36.5 ± 13.0 years; body mass index (BMI); 20.6 ± 1.2 kg/m2]. In experiment 2, we performed a randomized-crossover intervention study to evaluate the effects of body pillow use on sleeping position and sleep architecture in 10 healthy young adults (age, 24.3 ± 7.8 years; BMI, 21.4 ± 1.7 kg/m2). Sleep architecture was characterized by polysomnography, and body positions were monitored using a sensor. Subjective sleep quality was evaluated with the Oguri-Shirakawa-Azumi sleep inventory, middle age and aged version. Results In experiment 1, body pillow use significantly reduced mean body pressure on the shoulder, hip, and whole body. In experiment 2, mean time spent in the supine, lateral, and prone body positions did not differ significantly between the 2 trials. Body pillow use, however, significantly extended the sustained time spent in the lateral body position compared with the control trial. Subjective sleep quality and sleep architecture did not differ significantly between the 2 trials, but body pillow use decreased the number of short (30 s) slow-wave sleep episodes. Conclusions Sleeping with a body pillow effectively extends sustained time in a lateral sleeping position and prevents segmentation of slow-wave sleep episodes.

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