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Effect of Perforating an Intake Pipe on the Interior Noise of a Passenger Car
Zhu Yawei,Lu Chihua,Liu Zhien,Xie Liping,Li Xiaolong 한국자동차공학회 2021 International journal of automotive technology Vol.22 No.4
The intake pipes designed by some experienced engineers have small holes. However, the role of these small holes is yet to be fully understood by most engineers. At present, the only research on this issue is also controversial. This work aims to reveal the effect of perforating an intake pipe on the interior noise and provide some suggestions to automotive engineers when applying this method. First, the effect of these small holes on the source strength of the intake nozzle and perforated region is theoretically analyzed. Thereafter, the noise transfer functions of the intake nozzle and perforated region to the target response point in the cab are measured on the basis of the reciprocity principle. Finally, the effect of perforating the intake pipe on the interior noise is studied by simulating the intake noise of the experimental car with an external sound source. Results show that perforating the intake pipe can increase the order noise component of the intake noise and reduce the mid-high frequency noise in the cab, thereby improving the powerful sound quality and reducing the feeling of noisy.
Design and Numerical Study of Hybrid Magnetic Source Disc-type Magnetorheological Valve
Xiaolong Yang,Yan Li,Youming Zhou,Shiying Zhou,Jiehong Zhu 한국자기학회 2023 Journal of Magnetics Vol.28 No.2
Magnetorheological valves are important components in hydraulic systems that provide precise position control. At present, the low-pressure drop performance of magnetorheological valves is the main problem limiting their application. To improve the pressure drop performance of magnetorheological valves, a hybrid magnetic source disc magnetorheological valve is proposed. The magnetic pressure drop model and viscous pressure drop model of the hybrid magnet source disc type magnetorheological valve based on the Bingham model are Derived. Magnetic field distributions in the damping channel of the hybrid magnet source disc type magnetorheological valve are obtained by using ANSYS finite element analysis software. The mathematical model of the relationship between pressure drop and magnetic induction intensity was established using Matlab software, and the effects of parameters such as effective current, axial damping gap, radial damping gap, and coil width on the pressure drop performance of disc-type magnetorheological valves with hybrid magnetic sources were numerically analyzed. The results show that the pressure drop of the disc magnetorheological valve with a hybrid magnetic source can reach 10.9935 MPa at the current I=3A, axial damping gap ga=1 mm, and radial damping gap gr=1.5 mm. Compared with the conventional disc magnetorheological valve, the pressure drop performance of the hybrid magnetic source disc magnetorheological valve is improved by 28 %, which provides ideas on how to improve the pressure drop performance of the magnetorheological valve.
Design and Performance Study of Hybrid Channel-valved Magnetorheological Dampers
Yan Li,Xiaolong Yang,Jiehong Zhu,Youming Zhou 한국자기학회 2023 Journal of Magnetics Vol.28 No.1
In order to solve the problem of low damping force caused by low utilization of magnetic field in traditional magnetorheological dampers, a hybrid channel valve type magnetorheological damper with circular channel and disk channel are proposed. The main content of this paper is to design the basic structure of mixed channel valve magnetorheological damper. The mathematical model of damping force based on Bingham plastic model was established from the design of magnetic circuits. The two-dimensional simulation model of MR Damper was established by using EMAG module in ANSYS finite element analysis software, and the magnetic circuit of mixed channel valve MR Damper was simulated and analyzed. The results show that the output damping force of the hybrid channel valve-type magnetorheological damper is 18 KN and the adjustable coefficient is 14.52 with the current I of 3A, the number of coil turns of 560, the axial damping gap of 1 mm and the radial damping gap of 1.5 mm.
Models of China’s E-Commerce in the Agricultural Sector : an Exploratory Study
Jin Wang,Xiaolong Zhu,Chen Zhang 보안공학연구지원센터 2016 International Journal of u- and e- Service, Scienc Vol.9 No.4
We first review the current literature on the status quo of China’s E-commerce in the agricultural sector. The model of farmers’ selection of stakeholders in agricultural E-commerce is analyzed based on incomplete contract theory and right to entry theory. We conclude that the development of agricultural E-commerce follows a dynamic evolutionary model. To gain the largest profits from E-commerce in agriculture, the farmers need to dynamically adjust the cooperative relationships with the stakeholders under a constantly changing economic environment.
CDH17 nanobodies facilitate rapid imaging of gastric cancer and efficient delivery of immunotoxin
Jingbo Ma,Xiaolong Xu,Chunjin Fu,Peng Xia,Ming Tian,Liuhai Zheng,Kun Chen,Xiaolian Liu,Yilei Li,Le Yu,Qinchang Zhu,Yangyang Yu,Rongrong Fan,Haibo Jiang,Zhifen Li,Chuanbin Yang,Chengchao Xu,Ying Long,J 한국생체재료학회 2022 생체재료학회지 Vol.26 No.4
Background: It is highly desirable to develop new therapeutic strategies for gastric cancer given the low survival rate despite improvement in the past decades. Cadherin 17 (CDH17) is a membrane protein highly expressed in cancers of digestive system. Nanobody represents a novel antibody format for cancer targeted imaging and drug delivery. Nanobody targeting CHD17 as an imaging probe and a delivery vehicle of toxin remains to be explored for its theragnostic potential in gastric cancer. Methods: Naïve nanobody phage library was screened against CDH17 Domain 1-3 and identified nanobodies were extensively characterized with various assays. Nanobodies labeled with imaging probe were tested in vitro and in vivo for gastric cancer detection. A CDH17 Nanobody fused with toxin PE38 was evaluated for gastric cancer inhibition in vitro and in vivo. Results: Two nanobodies (A1 and E8) against human CDH17 with high affinity and high specificity were successfully obtained. These nanobodies could specifically bind to CDH17 protein and CDH17-positive gastric cancer cells. E8 nanobody as a lead was extensively determined for tumor imaging and drug delivery. It could efficiently co-localize with CDH17-positive gastric cancer cells in zebrafish embryos and rapidly visualize the tumor mass in mice within 3 h when conjugated with imaging dyes. E8 nanobody fused with toxin PE38 showed excellent anti-tumor effect and remarkably improved the mice survival in cell-derived (CDX) and patient-derived xenograft (PDX) models. The immunotoxin also enhanced the anti-tumor effect of clinical drug 5-Fluorouracil. Conclusions: The study presents a novel imaging and drug delivery strategy by targeting CDH17. CDH17 nanobodybased immunotoxin is potentially a promising therapeutic modality for clinical translation against gastric cancer.
The Phylotype of Thermus from the Rehai Geothermal Area, Tengchong, China
Guo, Chunlei,Wang, Tao,Zhu, Wei,Zhang, Donghua,Cui, Xiaolong,Xu, Lihua,Peng, Qian The Microbiological Society of Korea 2003 The journal of microbiology Vol.41 No.2
Through enrichment on two nutrient agars, 57 Thermus isolates were recovered from 15 hot spring samples taken from the Rehai geothermal area, Tengchong, China. Unique growth characteristics were observed when the strains were transferred from YIM14 medium to Thermus medium. Phylogenetic analysis showed that the 16S rDNA sequences of the isolates and clones from the Rehai geothermal area farmed a monophyletic group on the phylogenetic tree. A secondary structure comparison showed that their 16S rRNAs have unique secondary structure characteristics.