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      • Factors Affecting Survival Time of Cholangiocarcinoma Patients: A Prospective Study in Northeast Thailand

        Woradet, Somkiattiyos,Promthet, Supannee,Songserm, Nopparat,Parkin, Donald Maxwell Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3

        Cholangiocarcinoma (CCA) is a major health problem and cause of death among people in Northeastern Thailand. In this prospective study 171 patients newly diagnosed with CCA by physicians in 5 tertiary hospitals in four provinces of northeastern of Thailand between February and July 2011 were followed up to January 2012. The outcome was survival time from diagnosis to death. A total of 758.4 person-months of follow-up were available. The mortality rate was 16.9 per 100 person-months (95%CI: 14.1-20.1). The median survival time among CCA patients was 4.3 months (95%CI: 3.3-5.1). Cox's proportional hazard model was used to study the independent effects of factors affecting survival time among patients. Statistically significant factors included advanced stage at diagnosis (HR: 2.5, 95%CI: 1.7-3.8), presentation with jaundice (HR: 1.7, 95%CI: 1.1-2.4) or ascites (HR: 2.8, 95%CI: 1.8-4.4), and positive serum carcinoembryonic antigen (HR: 2.3, 95%CI: 1.2-4.3). Patients who had received standard treatment had a better prognosis that those who did not (HR: 0.5, 95%CI: 0.3-0.7).

      • Evaluation of Cholangiocarcinoma Risk and its Related Factors In Wetland Geographical Communities of Ubon Ratchathani, Thailand

        Songserm, Nopparat,Woradet, Somkiattiyos,Bureelerd, Onanong,Charoenbut, Pattaraporn Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.4

        Wetland geographical areas have a higher incidence of Opisthorchis viverrini-associated cholangiocarcinoma (CCA), confirmed by data from geographic information systems, than other areas. Behavioral data also indicate that people in these areas traditionally eat uncooked freshwater fish dishes, a vehicle for O. viverrini infection. The best approach to reducing CCA incidence is decreasing risk factors together with behavior alteration. Evaluation of CCA risk and its related factors are first needed for planning the prevention and control programs in the future. We therefore aimed to evaluate the CCA risk and explore its related factors among people in wetland communities of Ubon Ratchathani, Thailand. A cross-sectional study was conducted between July and August 2014. In total 906 participants, with informed consent, completed questionnaires. Overall risk of CCA was determined by multiplying odds ratios (ORs) of the risk factors for CCA from literature reviews. A mean score of 5.95 was applied as the cut-off point. Assessment of factors related to overall risk of CCA was accomplished using conditional logistic regression. Of all participants, 60.15% had a high level of the overall risk of CCA. Factors related to the overall risk of CCA were gender (p<0.001), marital status (p<0.001), perceived susceptibility (p=0.043) and prevention behavior for CCA (p<0.001). In conclusion, most participants in this community had a high level of overall risk of CCA. Therefore, integrated prevention and control programs continue to be urgently required.

      • Community Participation in Cholangiocarcinoma Prevention in Ubon Ratchathani, Thailand: Relations with Age and Health Behavior

        Songserm, Nopparat,Bureelerd, Onanong,Thongprung, Sumaporn,Woradet, Somkiattiyos,Promthet, Supannee Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.16

        A high prevalence of Opisthorchis viverrini infection is usually found in wetland geographical areas of Thailand where people have traditional behavior of eating uncooked freshwater fish dishes which results in cholangiocarcinoma (CCA) development. There were several approaches for reducing opisthorchiasis-linked CCA, but the prevalence remains high. To develop community participation as a suitable model for CCA prevention is, firstly, to know what factors are related. We therefore aimed to investigate factors associated with the community participation in CCA prevention among rural residents in wetland areas of Ubon Ratchathani, Thailand. This was a cross-sectional analytic study. All participants were 30-69 years of age, and only one member per house was invited to participate. A total of 906 participants were interviewed and asked to complete questionnaires. Independent variables were socio-demographic parameters, knowledge, health belief and behavior to prevent CCA. The dependent variable was community participation for CCA prevention. Descriptive statistics were computed as number, percentage, mean and standard deviation. Associations were assessed using logistic regression analysis with a P-value <0.05 considered statistically significant. Of all the participants, more than 60% had regularly participated in activities to prevent CCA following health officials advice. Age and health behavior to prevent CCA were factors associated with community participation for CCA (p<0.001). Both factors will be taken into consideration for community participation approaches for CCA prevention through participatory action research (PAR) in future studies.

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        A Meta-Analysis of the Effects of Dance Programs on Physical Performance: Appropriate Health Promotion for Healthy Older Adults

        Suparat Sooktho,Nopparat Songserm,Somkiattiyos Woradet,Wanich Suksatan 대한노인병학회 2022 Annals of geriatric medicine and research Vol.26 No.3

        Background: Dancing is a type of physical activity that has been associated with physical benefits in older adults. Regular dancing can help maintain physical function and improve the quality of life in this population. This review evaluated randomized control trials (RCTs) of the effectiveness of dance programs on the physical function of healthy older adults. Methods: We systematically searched four databases (PubMed, Google Scholar, Embase, and ThaiLis) through December 2021 for primary studies evaluating dance programs in healthy older adults aged 60 years and over. The meta-analysis used a random-effects model to compute the effect sizes using a forest plot and Cochran’s Q and I2 statistics as heterogeneity measures. Results: Eight types of dance programs showed significantly improved physical function. Muscle strength was assessed using the five times sit-to-stand test (I2=89%; p=0.003), chair-sit-to-stand-30S test (I2=75%; p=0.006), and 30-s arm curl test (I2=22%; p=0.260). Static balance was evaluated using the Berg-balance scales test (I2=0%; p=0.620) and the one-leg-stand test (I2=32%; p=0.220). Dynamic balance was tested based on the time up-and-go and eight-foot up-and-go tests (I2=51%; p=0.110). Flexibility was assessed based on the back-scratch (I2=56%; p=0.130) and sit-and-reach test (I2=0%; p=0.930). Conclusion: Dance exercise programs improved muscle strength, balance, and flexibility. Such programs are effective and safe for healthy older adults for use as daily exercise to promote health. Therefore, researchers, healthcare providers, and policymakers should establish properly organized dance interventions to improve physical function in healthy older adults.

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