동북아 피더네트워크의 Win-win전략에 관한 연구

장우준(Woo-jun jang),전찬용(Chan-Yong jeon),김태원(Tae-Won Kim),곽규석(Kyu-Seok Kwak),남기찬(Ki-Chan Nam) 한국항해항만학회 2006 한국항해항만학회 학술대회논문집 Vol.3 No.1

최근 중국은 양산항을 개장하여 선사 유치를 위한 다양한 혜택을 제공하고, 일본은 "수퍼중추항만 육성계획“을 세워 항만의 효율성을 바탕으로 비용을 낮추려는 노력을 하고 있다. 또한 선박의 대형화에 의한 중심항만(Hub Port) 위주의 기항과 북중국의 대량 물량 발생지역에 대한 직기항 경향으로 동북아 항만간의 경쟁이 더욱더 치열해 지고 있으며 동북아 역내 피더네트워크 강화의 필요성이 제기되고 있다. 따라서, 본 연구에서는 유럽 피더네트워크 전략 사례를 바탕으로 동북아 피더시장 현황을 파악하고 동북아 피더네트워크 구조를 분석함으로써 동북아 역내 항만 및 선사간의 과당경쟁을 지양하고 서로 Win-Win할 수 있는 터미널의 전략적 활용, 선사간 제휴 확대, 항만간 협력 강화를 위한 구체적인 전략을 제시하였다. Recently, China opened Yangshan port and provides a variety of benefits for shipping companies. Japan plans to reduce logistics costs and improve efficiency through the established "super major ports" project. According to the "hub and spokes" system, the number of direct calls toward North-Chinese ports are increasing. This changing environment has negative effects on the amount of transshipment cargos in Korean ports. In order to make a hub port of a domestic port, it is necessary to develop northeast Asian feeder networks. Therefore, this paper analyzes the structure of northeast Asian feeder networks through the case study of European feeder networks strategy. Finally, we suggests the plans to reinforce feeder networks, which are strategic terminal operation, strategic alliances between shipping companies and port co-operation, for win-win strategy in the competitive northeast Asian market.

고랭지 농업 용수확보를 위한 소규모 빗물 이용시설 적용방안

전계원(Kye Won Jun)(全桂元),장창덕(Chang Deok Jang)(張昌德),정승권(Seung Kwon Jung)(鄭承權),전병희(Byong Hee Jun)(田炳熙) 위기관리 이론과 실천 2013 Crisisonomy Vol.9 No.8

최근 기후변화로 지난 2009년과 2012년에 강원도 태백시에서는 가뭄으로 인하여 엄청난 피해를 경험한 적이 있다. 또한 가뭄과 장마의 예측은 점점 더 어려워져 가는 실정이다. 특히 태백시의 87일간의 가뭄과 제한급수에 따른 피해액은 일상생활 134억원, 산업부문 338억원, 공공부문 47억원, 정신적ㆍ사회적 피해 1, 430억원 등 총 1, 949억원에 달하는 것으로 분석되었다. 태백시에 또 다른 큰 문제점은 가뭄으로 인한 고랭지 농업 피해로 인한 손실이다. 고랭지 배추를 생산하는 태백시는 우리나라 유일의 고산지역의 도시로서, 고랭지 농업이 특히 발달한 지역이다. 특히 태백 고랭지 배추는 태백시 농산품의 95.9%, 총 경지면적의 86.6%를 차지하고 있으므로, 배추의 생산성이 태백시 농산품 생산성을 대변한다고 할 수 있다. 본 연구에서는 태백시의 공공기관과 고랭지 농업 지역을 직접 방문하여 소규모 빗물 이용 시설에 대한 현황조사 및 시설의 상태를 점검하고 가뭄발생시 고랭지 농업지역의 피해를 최소화 할 수 있도록 소규모 빗물 이용 시설의 적용 방안 및 효과를 분석하였다. Recently, drought and rainy season are getting more serious. It is getting hard to forecast about drought because drought frequency is getting shorter than before. In 2009(winter) and 2012(summer), Taebaek-si was suffered from enormous damage due to the drought. Particularly, in 2009, cost of damage due to drought and restriction on water supply for 87days were estimated daily life sector 134 billion won, industry sector 338 billion won, the public sector 47 billion won, mental and social damage 1, 430 billion won. The other big issue of Taebaek is decrease in products of Highland Agricultural caused by the drought. Highland chinese cabbage which is the most important agricultural product in Taebaek-si account for 95.9% of all agricultural production of Taebaek-si and account for 86.6% of all gross area. For this reason, chinese cabbage of Taebaek-si is tropical agricultural product and is in charge of supply cabbage definitely. It is considered that if small scale rainwater harvesting system would be installed in highland agriculture area, it could reduce damage of drought at low cost and damage of cabbage would be decrease by system. For this study, We have researched regarding current status of Small Scale Rainwater Harvesting System of Highland Agriculture area in Taebaek-si and have compared with the amount of damage and installation cost in case of drought for the beneficial effects of Small Scale Rainwater Harvesting System, flexible supply of water and damage minimization of agricultural products.

The Spring-Connected Rigid Block Model Based Automatic Synthesis of Planar Linkage Mechanisms: Numerical Issues and Remedies

Jun Nam, Sang,Jang, Gang-Won,Young Kim, Yoon ASME International 2012 Journal of Mechanical Design Vol.134 No.5

An Enhanced Observed Time Difference of Arrival Based Positioning Method for 3GPP LTE System

WON, Kyung-Hoon,JANG, Jun-Hee,CHOI, Hyung-Jin 'Institute of Electronics, Information and Communi 2012 IEICE TRANSACTIONS ON COMMUNICATIONS - Vol.eb95 No.3

Gene expression and DNA methylation status of chicken primordial germ cells.

Jang, Hyun-Jun,Seo, Hee Won,Lee, Bo Ram,Yoo, Min,Womack, James E,Han, Jae Yong Humana Press 2013 Molecular biotechnology Vol.54 No.2

<P>DNA methylation reprogramming of primordial germ cells (PGCs) in mammals establishes monoallelic expression of imprinting genes, maintains retrotransposons in an inactive state, inactivates one of the two X chromosomes, and suppresses gene expression. However, the roles of DNA methylation in chickens PGCs are unknown. In this study, we found a 1.5-fold or greater difference in the expression of 261 transcripts when comparing PGCs and chicken embryonic fibroblasts (CEFs) using an Affymetrix GeneChip Chicken Genome Array. In addition, we analyzed the methylation patterns of the regions ~5-kb upstream of 261 sorted genes, 51 of which were imprinting homologous loci and 49 of which were X-linked homologous loci in chicken using the MeDIP Array by Roche NimbleGen. Seven hypomethylated and five hypermethylated regions within the 5-kb upstream regions of 261 genes were found in PGCs when compared with CEFs. These differentially methylated regions were restrictively matched to differentially expressed genes in PGCs. We also detected 203 differentially methylated regions within imprinting and X-linked homologous regions between male PGCs and female PGCs. These differentially methylated regions may be directly or indirectly associated with gene expression during early embryonic development, and the epigenetic difference could be evolutionally conserved between mammals and birds.</P>

High-dose stereotactic body radiotherapy correlates increased local control and overall survival in patients with inoperable hepatocellular carcinoma

Jang, Won Il,Kim, Mi-Sook,Bae, Sun Hyun,Cho, Chul Koo,Yoo, Hyung Jun,Seo, Young Seok,Kang, Jin-Kyu,Kim, So Young,Lee, Dong Han,Han, Chul Ju,Kim, Jin,Park, Su Cheol,Kim, Sang Bum,Cho, Eung-Ho,Kim, Youn BioMed Central 2013 Radiation oncology Vol.8 No.-

<P><B>Background</B></P><P>Recent studies using stereotactic body radiotherapy (SBRT) for hepatocellular carcinoma (HCC) have reported high tumor response and local control. However, the optimal SBRT dose remains unknown, and it is still not clear whether a dose response relationship for local control (LC) and overall survival (OS) exist or not. We performed this study to determine whether a dose response relationship for LC and OS is observed in SBRT for inoperable HCC.</P><P><B>Methods</B></P><P>Between 2003 and 2011, 108 patients with HCC were treated with SBRT. All patients were unsuitable for surgery or local ablation and had incomplete response to transarterial chemoembolization. Eighty-two patients with a longest tumor diameter (LD) less than or equal to 7.0 cm who were treated with 3-fraction SBRT and were analyzed. This cohort comprised 74 Child-Turcotte-Pugh (CTP) class A patients and 8 CTP class B7 patients. The median LD was 3.0 cm (range, 1.0–7.0 cm), and the median dose was 51 Gy (range, 33–60 Gy).</P><P><B>Results</B></P><P>LC and OS rates at 2 years after SBRT were 87% and 63%, respectively, with a median follow-up duration of 30 months for all patients. The 2-year LC/OS rates for patients treated with doses of > 54, 45–54, and < 45 Gy were 100/71, 78/64, and 64%/30%, respectively (p = .009/p < .001). Multivariate analysis revealed that the SBRT dose (p = .005) and Barcelona Clinic Liver Cancer stage (p = .015) were significant prognostic factors for OS. Correlation analysis revealed a positive linear relationship between the SBRT dose and LC (p = .006, R = .899)/OS (p = .002, R = .940) at 2 years. Based on the tumor-control probability model, a dose of 54.8 Gy provides 2-year LC with a 90% probability. Five patients experienced grade 3 or higher gastrointestinal toxicity, and 6 had deteriorating of CTP score by greater than or equal to 2 within 3 months of SBRT.</P><P><B>Conclusions</B></P><P>This study demonstrated a dose response relationship for LC and OS with SBRT for HCC. Higher LC rates resulting from an increased dose may translate into survival benefits for patients with HCC.</P>

Peptidylarginine deiminase inhibition impairs Toll-like receptor agonist-induced functional maturation of dendritic cells, resulting in the loss of T cell–proliferative capacity: a partial mechanism with therapeutic potential in inflammatory setti

Jang, Byungki,Kim, Ho Won,Kim, Jong-Seok,Kim, Woo Sik,Lee, Bo Ryeong,Kim, Sojeong,Kim, Hongmin,Han, Seung Jung,Ha, Sang-Jun,Shin, Sung Jae Federation of American Societies for Experimental 2015 Journal of Leukocyte Biology Vol.97 No.2

<P>Cl-amidine, which is a small-molecule inhibitor of PAD, has therapeutic potential for inflammation-mediated diseases. However, little is known regarding the manner by which PAD inhibition by Cl-amidine regulates inflammatory conditions. Here, we investigated the effects of PAD inhibition by Cl-amidine on the functioning of DCs, which are pivotal immune cells that mediate inflammatory diseases. When DC maturation was induced by TLR agonists, reduced cytokine levels (IL-6, IL-1 beta, and IL-12p70) were observed in Cl-amidine-treated DCs. Cl-amidine-treated, LPS-activated DCs exhibited alterations in their mature and functional statuses with up-regulated antigen uptake, down-regulated CD80, and MHC molecules. In addition, Cl-amidine-treated DCs dysregulated peptide-MHC class formations. Interestingly, the decreased cytokines were independent of MAPK/NF-kappa B signaling pathways and transcription levels, indicating that PAD inhibition by Cl-amidine may be involved in post-transcriptional steps of cytokine production. Transmission electron microscopy revealed morphotypical changes with reduced dendrites in the Cl-amidine-treated DCs, along with altered cellular compartments, including fragmented ERs and the formation of foamy vesicles. Furthermore, in vitro and in vivo Cl-amidine treatments impaired the proliferation of naive CD4(+) and CD8(+) T cells. Overall, our findings suggest that Cl-amidine has therapeutic potential for treating inflammation-mediated diseases.</P>

Application of Cerenkov radiation generated in plastic optical fibers for therapeutic photon beam dosimetry.

Jang, Kyoung Won,Yagi, Takahiro,Pyeon, Cheol Ho,Yoo, Wook Jae,Shin, Sang Hun,Jeong, Chiyoung,Min, Byung Jun,Shin, Dongho,Misawa, Tsuyoshi,Lee, Bongsoo SPIE--the International Society for Optical Engine 2013 Journal of biomedical optics Vol.18 No.2

<P>A Cerenkov fiber-optic dosimeter (CFOD) is fabricated using plastic optical fibers to measure Cerenkov radiation induced by a therapeutic photon beam. We measured the Cerenkov radiation generated in optical fibers in various irradiation conditions to evaluate the usability of Cerenkov radiation for a photon beam therapy dosimetry. As a results, the spectral peak of Cerenkov radiation was measured at a wavelength of 515 nm, and the intensity of Cerenkov radiation increased linearly with increasing irradiated length of the optical fiber. Also, the intensity peak of Cerenkov radiation was measured in the irradiation angle range of 30 to 40 deg. In the results of Monte Carlo N-particle transport code simulations, the relationship between fluxes of electrons over Cerenkov threshold energy and energy deposition of a 6 MV photon beam had a nearly linear trend. Finally, percentage depth doses for the 6 MV photon beam could be obtained using the CFOD and the results were compared with those of an ionization chamber. Here, the mean dose difference was about 0.6%. It is anticipated that the novel and simple CFOD can be effectively used for measuring depth doses in radiotherapy dosimetry.</P>

Design and fabrication of a microstrip patch antenna with a low radar cross section in the X-band

Jang, Hong-Kyu,Lee, Won-Jun,Kim, Chun-Gon Institute of Physics Publishing 2011 Smart materials & structures Vol.20 No.1

<P>In this study, the authors developed a radar absorbing method to reduce the antenna radar cross section (RCS) without any loss of antenna performance. The new method was based upon an electromagnetic bandgap (EBG) absorber using conducting polymer (CP). First, a microstrip patch antenna was made by using a copper film and glass/epoxy composite materials, which are typically used for load-bearing structures, such as aircraft and other vehicles. Then, CP EBG patterns were also designed that had a 90% electromagnetic (EM) wave absorbing performance within the X-band (8.2–12.4 GHz). Finally, the CP EBG patterns were printed on the top surface of the microstrip patch antenna. The measured radar absorbing performance of the fabricated patch antenna showed that the frontal RCS of the antenna declined by nearly 95% at 10 GHz frequency while the CP EBG patterns had almost no effect on the antenna’s performance. </P>

Layer-specific serotonergic facilitation of IPSC in layer 2/3 pyramidal neurons of the visual cortex.

Jang, Hyun-Jong,Cho, Kwang-Hyun,Park, Sung-Won,Kim, Myung-Jun,Yoon, Shin Hee,Rhie, Duck-Joo American Physiological Society [etc.] 2012 journal of neurophysiology Vol.22 No.-

<P>Serotonin (5-hydroxytryptamine, 5-HT) inhibits the induction of long-term synaptic plasticity in layer 2/3 of the visual cortex at the end of its critical period in rats. However, the cellular and molecular mechanisms remain unclear. Since inhibitory influence is crucial in the induction of synaptic plasticity, the effect of 5-HT on inhibitory transmission was investigated in layer 2/3 pyramidal neurons of the primary visual cortex. The amplitude of inhibitory postsynaptic current (IPSC), but not excitatory postsynaptic current, evoked by stimulation of the underlying layer 4, was increased by 20% with a bath application of 5-HT. The amplitude of miniature IPSC was also increased by the application of 5-HT, while the paired-pulse ratio was not changed. The facilitating effect of 5-HT on IPSC was mediated by the activation of 5-HT(2) receptors. An increase in intracellular Ca(2+) via release from inositol 1,4,5-trisphosphate (IP(3))-sensitive stores, which was confirmed by confocal Ca(2+) imaging, and activation of Ca(2+)/calmodulin-dependent kinase II (CaMKII) were involved in the facilitation of IPSC by 5-HT. However, 5-HT failed to facilitate IPSC evoked by the stimulation of layer 1. These results suggest that activation of 5-HT(2) receptors releases intracellular Ca(2+) via IP(3)-sensitive stores, which facilitates GABA(A)ergic transmission via the activation of CaMKII in layer 2/3 pyramidal neurons of the visual cortex in a layer-specific manner. Thus facilitation of inhibitory transmission by 5-HT might be involved in regulating the information flow and the induction of long-term synaptic plasticity, in a pathway-specific manner.</P>