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RISS 인기검색어
- 검색키워드
- 저자 : Vikram Goyal (검색결과 2 건)
- 무료
- 기관 내 무료
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AI-CoV Study: Autoimmune Encephalitis Associated With COVID-19 and Its Vaccines—A Systematic Review
MM Samim,Debjyoti Dhar,Sheetal Goyal,Treshita Dey,Naznin Parvin,Rutul D. Shah,Vikram Singh,Sampurna Chowdhury,Bhavesh Mohan Lal,Nibu Varghese,Abhishek Gohel,Abhishek Chowdhury,Aritra Chatterjee,Shahya 대한신경과학회 2022 Journal of Clinical Neurology Vol.18 No.6
Background and Purpose Autoimmune encephalitis (AIE) following coronavirus disease 2019 (COVID-19) is an underexplored condition. This study aims to systematically review the clinico-investigational and pathophysiologic aspects of COVID-19 and its vaccines in association with AIE, and identify the factors predicting neurological severity and outcomes. Methods Relevant data sources were searched using appropriate search terms on January 15, 2022. Studies meeting the criteria for AIE having a temporal association with COVID-19 or its vaccines were included. Results Out of 1,894 citations, we included 61 articles comprising 88 cases: 71 of COVID-19-associated AIE, 3 of possible Bickerstaff encephalitis, and 14 of vaccine-associated AIE.There were 23 definite and 48 possible seronegative AIE cases. Anti-NMDAR (N-methyl-D-aspartate receptor; n=12, 16.9%) was the most common definite AIE. Males were more commonly affected (sex ratio=1.63) in the AIE subgroup. The neurological symptoms included alteredmental state (n=53, 74.6%), movement disorders (n=28, 39.4%), seizures (n=24, 33.8%), behavioural (n=25, 35.2%), and speech disturbances (n=17, 23.9%). The median latency to AIE diagnosis was 14 days (interquartile range=4–22 days). Female sex and ICU admission had higherrisks of sequelae, with odds ratio (OR) of 2.925 (95% confidence interval [CI]=1.005–8.516)and 3.515 (95% CI=1.160–10.650), respectively. Good immunotherapy response was seen in42/48 (87.5%) and 13/13 (100%) of COVID-19-associated and vaccine-associated AIE patients, respectively. Sequelae were reported in 22/60 (36.7%) COVID-19 associated and 10/13 (76.9%) vaccine-associated cases. Conclusions The study has revealed diagnostic, therapeutic, and pathophysiological aspects of AIE associated with COVID-19 and its vaccines, and its differences from postinfectious AIE.
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Right Atrial Paraganglioma: An Extremely Rare Primary Cardiac Neoplasm Mimicking Myxoma
Ashok Garg,Deepika Mishra,Manish Bansal,Hari Ram Maharia,Vikram Goyal 한국심초음파학회 2016 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.24 No.4
In this report, we present a case of 35-year-old lady who had presented with atypical chest pain and exertional breathlessness forpast six months. Transthoracic and transesophageal echocardiograms showed a well-circumscribed, echo-dense mass in the rightatrium, attached to the interatrial septum at the level of atrioventricular junction and in the vicinity of coronary sinus ostium. Sheunderwent successful resection of the cardiac mass. Histopathology revealed paraganglioma, which was reconfirmed by immunohistochemistrystudy. This represents an extremely rare presentation as primary cardiac tumors are 20-times less common thanmetastatic tumors and paraganglioma is one of the rarest primary cardiac tumors, accounting for < 1% of all cases.
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