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RISS 인기검색어
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- 저자 : Vera Daniela D (검색결과 2 건)
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Daniela Jones-Dias,Vera Manageiro,Eugénia Ferreira,Deolinda Louro,Antibiotic Resistance Surveillance Program in Portugal Participants,Manuela Caniça 한국미생물학회 2014 The journal of microbiology Vol.52 No.6
A group of 124 Enterobacteriaceae isolates resistant to thirdgeneration cephalosporins, and collected in distinct healthcare facilities of different Portuguese regions was analysed. The great majority of the isolates were also resistant to fourthgeneration cephalosporins (83.9%), monobactam (96%),amoxicillin plus clavulanic acid (85.5%), and piperacillinplus tazobactam (66.9%). Overall, 84.7% (105/124) were multidrugresistant. Molecular methods enabled us to identify86.3% (107/124) extended-spectrum β-lactamases (ESBL)producers, revealing a diversity of class A β-lactamases fromdifferent families, like TEM (TEM-1, TEM-10, TEM-24, andTEM-52), SHV (SHV-1, SHV-12, and SHV-28), CTX-M(CTX-M-1, CTX-M-9, CTX-M-14, CTX-M-15, and CTXM-32), and GES (GES-1). We have also detected class C enzymeslike plasmid-mediated AmpC β-lactamases (PMAβs,DHA-1, and CMY-2) and chromosomal AmpCs in Enterobacterand Citrobacter spp. The PMAβ genetic context mappingsuggests association with mobile elements, plasmid importationand the potential emergence of these β-lactamases. The most prevalent β-lactamase detected was CTX-M-15(66.1%) and in 41.1% of the isolates it was associated withTEM-, OXA-type β-lactamases and Aac(6)’-Ib-cr, whichmight indicate that the respective genotype has settled inour country. Indeed, CTX-M-15 was distributed amongstdistinct clinical settings of several health care facilities(93.5%) from various regions. We provide evidence of a concerningclinical situation that includes vast occurrence ofESBLs, the settling of CTX-M β-lactamases, and the reportof plasmidic and chromosomal AmpC in Portugal.
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Flow Diverter Treatment for Non-Ruptured Carotid Aneurysms: Efficacy and Safety
López-Callejas Orlando,Ortiz-Giraldo Andres F,Vera Daniela D,Ramirez-Rojas Diego A,Villamizar-Barahona Ana B,Ferreira-Prada Carlos A.,Galvis Melquizidel,Vargas-Pérez Oliverio,Serrano-Gómez Sergio,Reye 대한신경중재치료의학회 2023 Neurointervention Vol.18 No.1
Purpose: Internal carotid artery (ICA) aneurysm treatment with a flow diverter (FD) has shown an adequate efficacy and safety profile, presenting high complete occlusion or near occlusion rates with low complications during follow-up. The purpose of this study was to evaluate the efficacy and safety of FD treatment in non-ruptured internal carotid aneurysms.Materials and Methods: This is a retrospective, single-center, observational study evaluating patients diagnosed with unruptured ICA aneurysms treated with an FD between January 1, 2014, and January 1, 2020. We analyzed an anonymized database. The primary effectiveness endpoint was complete occlusion (O’Kelly–Marotta D, OKM-D) of the target aneurysm through 1-year follow-up. The safety endpoint was the evaluation of modified Rankin Scale (mRS) 90 days after treatment, considering a favorable outcome an mRS 0-2.Results: A total of 106 patients were treated with an FD, 91.5% were women; the mean follow- up was 427.2±144.8 days. Technical success was achieved in 105 cases (99.1%). All patients included had 1-year follow-up digital subtraction angiography control; 78 patients (73.6%) completed the primary efficacy endpoint by achieving total occlusion (OKM-D). Giant aneurysms had a higher risk of not achieving complete occlusion (risk ratio, 3.07; 95% confidence interval, 1.70 - 5.54]). The safety endpoint of mRS 0-2 at 90 days was accomplished in 103 patients (97.2%).Conclusion: Treatment of unruptured ICA aneurysms with an FD showed high 1-year total occlusion results, with very low morbidity and mortality complications.
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