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Ganesh, M.,Aziz, A.S.,Ubaidulla, U.,Hemalatha, P.,Saravanakumar, A.,Ravikumar, R.,Peng, M.M.,Choi, E.Y.,Jang, H.T. THE KOREAN SOCIETY OF INDUSTRIAL AND ENGINEERING 2016 JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY -S Vol.39 No.-
<P>Novel silver nanoparticles-decorated chitosan (CS)-polyvinyl alcohol (PVA) composite electrospun nanofibers, loaded with sulfanilamide for enhanced wound healing have been developed. Herein, formic acid was used as a reducing agent to produce in situ colloidal silver nanoparticles (AgNPs) in the composite polymeric solution with the active agent sulfanilamide. The prepared electrospun fibers were characterized using scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction, ultraviolet spectroscopy, and thermal gravimetric analysis (TG). Further, in vitro release, antimicrobial properties and in vivo wound healing activity were evaluated. The results revealed that the composite fibers displayed a synergistic antibacterial and wound healing activities. (C) 2016 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.</P>
Mani Ganesh,Abidov Sch Aziz,Udumansha Ubaidulla,Pushparaj Hemalatha,Arthanari Saravanakumar,Rramaswamy Ravikumar,Mei Mei Peng,최은영,장현태 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.39 No.-
Novel silver nanoparticles-decorated chitosan (CS)-polyvinyl alcohol (PVA) composite electrospunnanofibers, loaded with sulfanilamide for enhanced wound healing have been developed. Herein, formicacid was used as a reducing agent to produce in situ colloidal silver nanoparticles (AgNPs) in thecomposite polymeric solution with the active agent sulfanilamide. The prepared electrospun fiberswere characterized using scanning electron microscopy (SEM), transmission electron microscopy (TEM),X-ray diffraction, ultraviolet spectroscopy, and thermal gravimetric analysis (TG). Further, in vitrorelease, antimicrobial properties and in vivo wound healing activity were evaluated. The results revealedthat the composite fibers displayed a synergistic antibacterial and wound healing activities.