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The Effect of Soybeans on the Anovulatory Cycle
Takafumi Kohama,Hiroto Kobayashi,Masaki Inoue 한국식품영양과학회 2005 Journal of medicinal food Vol.8 No.4
We treated 36 outpatients, suffering from secondary amenorrhea, who had no menstruation or no ovulation formore than 6 months before consulting our clinic. After polycystic ovary syndrome, hyperprolactinemia, and other ovarian dis-orders that require medical treatment had been ruled out through smear test examinations of the uterine cervix and uterinemyoma, ovarian tumor, and endometriosis had been checked for with ultrasonography and serum CA-125, the subjects beganto take 6 g/day of black soybean in micropowder form for 6 months (S group). We estimated the ovular improvement of the-ses patients, observing basal body temperature (BBT) and follicular development with ultrasonography during the menstrualcycle as the indexes for ovulation and compared them with 34 patients with no treatment (C group). In the S group, improvedovulation was seen in 12 patients, four patients became pregnant, and three patients had anovular menstruation within 3 monthsafter starting to take soybean powder. The periods of first ovulation were 66. 12 days. After ovulation started, all subjectshad regular menstruations and ovulation, with more than a 7-day high phase in BBT. On the other hand, in the C group, im-proved ovulation was seen in two patients, and two patients had anovular menstruation. In conclusion, black soybean has thepotential to improve the anovular menstrual cycle.