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        Determinants of Postoperative Spinal Height Change among Adult Spinal Deformity Patients with Long Construct Circumferential Fusion

        Rentenberger Colleen,Okano Ichiro,Salzmann Stephan N.,Shirahata Toshiyuki,Reisener Marie-Jacqueline,Shue Jennifer,Sama Andrew A.,Cammisa Frank P.,Girardi Federico P.,Hughes Alexander P. 대한척추외과학회 2021 Asian Spine Journal Vol.15 No.2

        Study Design: Retrospective clinical study. Purpose: To describe postoperative height changes and identify the predictive factors of spinal height (SH) changes among patients with adult spinal deformity (ASD) who underwent circumferential lumbar fusion with instrumentation. Overview of Literature: Postoperative height changes remain an important issue after spinal fusion surgery that affects the overall satisfaction with surgery. Previous studies of postoperative height change have focused exclusively on young patients with adolescent idiopathic scoliosis (AIS). Methods: We retrospectively reviewed the clinical and imaging data of ASD patients who underwent lumbar corrective circumferential fusion of ≥3 levels (n=106). SH was defined as the vertical distance between C2 and S1 on a standing lateral image. As potential predictors of postoperative height change, the number of lateral lumbar interbody fusion (LLIF) levels, change in spino-pelvic parameters, total number of levels fused, and pedicle subtraction osteotomies (PSO) were documented. Univariate and multivariate linear regression analyses were performed to identify the predictors of postoperative height change. Results: The mean SH change was −2.39±50.8 mm (range, −160 to 172 mm). The univariate analyses showed that the number of LLIF levels (coefficient=10.9, p =0.03), the absolute coronal vertical axis change (coefficient=0.6, p =0.01), and the absolute Cobb angle change (coefficient=−0.9, p =0.03) were significant predictors for height change. Patients with PSOs (n=14) tended to have a shorter height postoperatively (coefficient=−26.1); however, this difference was not significant (p =0.07). Multivariate analyses conducted with variables of p <0.20 showed that pelvic tilt (PT) change is an independent contributor to SH change (coefficient=−0.99, p =0.04, R2 =0.11). Conclusions: Utilizing a modified definition of SH used in previous AIS studies, we demonstrated that patients with ASD lose SH postoperatively and that PT change was an independent contributor of SH change.

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        Pursuit of optimal synthetic conditions for obtaining colloidal zero-valent iron nanoparticles by scanning pulsed laser ablation in liquids

        Ruth Lahoz,Eva Natividad,Álvaro Mayoral,Christian Rentenberger,Daniel Díaz-Fernández,Eduardo J. Félix,Leonardo Soriano,Wolfgang Kautek,Oscar Bomati-Miguel 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.81 No.-

        Liquid-Assisted Pulsed Laser Ablation (LA-PLA) is a promising top-down method to directly synthesizecolloidal dispersions of nanoparticles in a eco-friendly manner. However, the role of LA-PLA synthesisparameters is not yet fully agreed. This work seeks to optimize the production of nanoscale zero-valentiron (nZVI) particles suitable for biomedical or environmental applications using nanosecond LA-PLA oniron targets with different ablation media, laser and target scanning parameters. The use of alcohols assolvents produces iron-iron oxide core-shell nanoparticles with amorphous cores, except for a smallcrystalline fraction corresponding to the biggest core sizes. Decreasing carbon chain length andcomplexity leads to a thinning of the carbonaceous material coatings and an increase of the colloidalstability and the nanoparticle productivity. Moreover, a decrease of solvent density and surface tensionallows obtaining reduced sizes and polydispersity values. Among, laser and scanning parameters, thepulse accumulation per spot displayed a clear effect in boosting size and productivity. As main outcome,aqueous dispersions with suitable colloidal properties are obtained, either by transferring to water ofoptimized nZVI particles produced in ethanol, or by direct formation of nZVI particles and in situ coatingwith hydrophilic molecules in aqueous solutions of these molecules.

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