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        Enhancing Sensitivity and Selectivity: Morphological Modification and Chemical Functionalization within Confined Structures

        Rafita Erli Adhawiyah,Jungchul Lee 한국정밀공학회 2024 International Journal of Precision Engineering and Vol.25 No.4

        Sensors are vital components in a wide variety of applications throughout our everyday lives. Two critical factors that contribute to their importance are sensitivity and selectivity. To achieve high-performance sensors, modification and functionalization of the sensing surface become imperative. The process involves altering the surface properties of the sensor and introducing a recognition element to optimize its response to the target analyte. However, when it comes to internal sensing surfaces, such as those found in microchannel-based sensors, challenges arise. Being narrow and confined makes the modification process particularly arduous. Accessing the internal surfaces for modification becomes difficult due to their small size, and achieving uniformity across the microchannel surface poses a considerable challenge. Overcoming these obstacles demands innovative fabrication techniques, specialized equipment, and precise control during the modification process. This paper will review the potential approaches for the modification and functionalization of the sensor surface, as well as offer a variety of strategies to effectively enhance the internal sensing surface.

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        Nozzle-based precision patterning with micro-/nano fluidics integrated cantilevers

        Juhee Ko,Nada Ben Fredj,Rafita Erli Adhawiyah,이정철 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.2

        As the requirements of micro-/nano printing technologies are continuously increasing, direct writing technologies on a submicron scale are drawing attention. One of the promising methods is a nozzle-based precision patterning with atomic force microscopy (AFM), which has the advantages of high position controllability including nozzle-to-substrate distance feedback under a nanometer scale. It uses a fluidic channel and a dispensing nozzle integrated with a cantilever structure for deflection monitoring. In this paper, we introduce micro/nanofluidics integrated cantilevers for nozzle-based precision patterning in several considerations: 1) numerous fabrication strategies for nozzle-integrated fluidic cantilevers; 2) methods for liquid transport; 3) methods for pattern formation; and 4) applications with various printing materials.

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