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Degradation of cyanobacterial toxin, microcystin LR, using chemical oxidants.
Pyo, Dongjin,Yoo, Jisun Marcel Dekker 2008 Journal of immunoassay & immunochemistry Vol.29 No.3
<P>Cyanobacterial toxins, microcystins, are very potent hepatotoxins and their occurrence has been reported all over the world. They could threaten human health when toxic Microcystis occurs in water supply reservoirs. In this study, the effects of several environmental factors on production and degradation of toxins produced by cyanobacteria in Lake Soyang have been studied. A new rapid quantification method of microcystins, using fluorescence for a detection signal and a lateral-flow-type immunochromatography as a separation system, was used. Chlorine, potassium permanganate, and hydrogen peroxide were used as chemical oxidants for the degradation of microcystin LR. When chlorine was used, the efficiency of degradation was the highest. The degradation reaction took 40 minutes.</P>
Production and Degradation of Cyanobacterial Toxin in Water Reservoir, Lake Soyang
Dongjin Pyo*,Jungeun Jin 대한화학회 2007 Bulletin of the Korean Chemical Society Vol.28 No.5
Cyanobacterial toxins, microcystins are very potent hepatotoxins and their occurrence has been reported all over the world. They could threaten human health when toxic Microcystis occurs in water supply reservoirs. In this study, the effects of several environmental factors on production and degradation of toxins produced by cyanobacteria in Lake Soyang have been studied. A new rapid quantification method of microcystins using fluorescence for a detection signal and a lateral-flow-type immunochromatography as a separation system was used. Culture age, temperature, light intensity, pH, N-nutrient concentration, P-nutrient concentration, iron and zinc concentration were the most importantly examined factors. The toxin content was the highest on 17-18 days and at temperatures between 20 oC and 25 oC, and at pH between 8.4 and 8.8.
Dongjin Pyo*,Geunyoung Park,Jongchon Choi,Changsuk Oh 대한화학회 2005 Bulletin of the Korean Chemical Society Vol.26 No.2
Different detection characteristics of fluorescence immunochromatography method and high performance liquid chromatography (HPLC) method for the analysis of cyanobacterial toxins were studied. In particular, low and high limits of detection, detection time and reproducibility and detectable microcystin species were compared when fluorescence immunochromatography method and high performance liquid chromatography method were applied for the detection of microcystin (MC), a cyclic peptide toxin of the freshwater cyanobacterium Microcystis aeruginosa. A Fluorescence immunochromatography assay system has the unique advantages of short detection time and low detection limit, and high performance liquid chromatography detection method has the strong advantage of individual quantifications of several species of microcystins.