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- 저자 : Omar Jiménez (검색결과 4 건)
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Jorge Chávez,Omar Jiménez Alemán,Martín Flores Martínez,Héctor J. Vergara‑Hernández,Luis Olmos,Pedro Garnica‑González,Didier Bouvard 대한금속·재료학회 2020 METALS AND MATERIALS International Vol.26 No.2
The design and fabrication of a bilayer Ti6Al4V–Ti6Al4V/30Ta component were performed by using the powder metallurgyprocess and solid-state sintering as the consolidation step. Phase change and sintering densifcation of the component werestudied by dilatometry. The addition of 30 vol% of Ta to the Ti6Al4V matrix had a noticeable efect over the microstructuraland mechanical properties of the alloy, which showed decrements of up to 12.2 and 21.5% in nano-hardness and elastic modulus, respectively. The decrement of these properties strongly afected the wear and corrosion performance of the component. Special attention was focused on the intermediate zone between layers denoted by a transition zone, which presented betterwear response because of the properties and microstructure caused by the gradient difusion of Ta. Ti6Al4V/30Ta alloyshowed an improved corrosion behaviour compared to Ti6Al4V alloy, decreasing 2.4 times their susceptibility to corrosionand about two orders of magnitude their corrosion rate. The bilayer component in this study is proposed as an alternative todecrease the consumption of expensive materials with improved properties.
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Analysis of Compression and Permeability Behavior of Porous Ti6Al4V by Computed Microtomography
Luis Olmos,Didier Bouvard,Jose Luis Cabezas‑Villa,Jose Lemus‑Ruiz,Omar Jiménez,Dante Arteaga 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.3
Porous materials were developed as a good alternative to replace different bones in the human body as they improve osseointegration,tissue ingrowth and simulate the mechanical properties of human bones. Such characteristics highly depend on thepore features and volume fraction. Samples with a pore volume fraction between 16 and 60% and a pore size distribution of100–500 μm were analyzed by computed microtomography. 3D images acquisition was performed at 10 μm pixel resolution,which permitted to observe the complete sample. Features like size, shape, orientation, connectivity and pore coordinationwere determined from the 3D image analysis. Compression behavior was evaluated by interrupted compression testing and,after that, new 3D images were acquired. In order to evaluate permeability, numerical simulations of flow throughout the3D images were carried out by using Avizo® software. It was found that shape and pore size distribution was similar in allsamples, showing good distribution of the pore formers inside the matrix. Full connectivity of pores was obtained with 32%volume fraction and above, and the coordination number follows the Artz model. The pores showed a radial orientation,which induces anisotropy in the flow properties. The compression showed two different behaviors, pore closing and porecoalescence. Values of permeability match with those reported for bones as well as the anisotropy in the radial and verticaldirections. It is concluded that the sample with 60 vol% of pores could be consider to be used for bone implants.
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María Elena Sánchez-Vergara,Diana Monserrat López-Romero,Pablo Vidal-García,Christian Jiménez-Jarquín,Aline Hernandez-García,Omar Jiménez-Sandoval 대한금속·재료학회 2017 ELECTRONIC MATERIALS LETTERS Vol.13 No.3
Hybrid devices consisting of metallophthalocyanines, MPcs(M=Zn, Cu), doped with a Tetrathiafulvalene (TTF) derivativeand dispersed in nylon 11 have been prepared by using a thermalevaporation technique. The effects of thermal relaxation on thestructure and morphology of the samples were studied by FT-IRspectroscopy, SEM and X-ray diffraction. The thermalrelaxation in nylon 11 produced a crystalline arrangement in theα- and β-form MPc molecules. Changes in conductivity of thedevices suggest the formation of alternative paths for carrierconduction. It was found that the temperature-dependent electriccurrent in Zn devices showed a semiconductor behavior. Finally,the optical direct and indirect band gap of these hybrid deviceswas evaluated from optical absorption measurements. The bandgap values were found to decrease from 3.7 to 1.38 eV (for theZnPc device), and from 1.9 to 1.1 eV (for the CuPc device), withthe addition of TTF in the polymeric matrix.
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Jorge Antonio Zamora Dominguez,Irma Olarte Carrillo,Rubén Ruiz Ramos,Christian Omar Ramos-Peñafiel,Luis Jiménez Zamudio,Ethel García Latorre,Federico Centeno Cruz,Adolfo Martínez Tovar 대한혈액학회 2023 Blood Research Vol.58 No.1
Background Leukemia is a neoplasm with high incidence and mortality rates. Mitotic death has been observed in tumor cells treated with chemotherapeutic agents. Ras family proteins participate in the transduction of signals involved in different processes, such as proliferation, differentiation, survival, and paradoxically, initiation of cell death. Methods This study investigated the effect of H-Ras expression on human T-cell acute lymphoblastic leukemia MOLT-4 cells. Cells were electroporated with either wild-type (Raswt) or oncogenic mutant in codon 12 exon 1 (Rasmut) versions of H-Ras gene and stained for morphological analysis. Cell viability was assessed using trypan blue staining and cell cycle analysis using flow cytometry. H-Ras gene expression was determined using quantitative real-time reverse transcription polymerase chain reaction. The t, ANOVA, and Scheffe tests were used for statistical analysis. Results Human T-cell acute lymphoblastic leukemia MOLT-4 cells showed nuclear fragmentation and presence of multiple nuclei and micronuclei after transfection with either wt or mutant H-Ras genes. Cell cycle analysis revealed a statistically significant increase in cells in the S phase when transfected with either wt (83.67%, P <0.0005) or mutated (81.79%, P <0.0001) H-Ras genes. Although similar effects for both versions of H-Ras were found, cells transfected with the mutated version died at 120 h of mitotic catastrophe. Conclusion Transfection of human T-cell acute lymphoblastic leukemia MOLT-4 cells with either normal or mutated H-Ras genes induced alterations in morphology, arrest in the S phase, and death by mitotic catastrophe.
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