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        The Effect of Bulk Electrospun Polycaprolactone-graphene Oxide Scaffold on the Healing of Defected Femur Cartilage on a Rabbit Model

        Farnaz Moradi,Adeleh Gholipour-Kanani,Najmeh Najmoddin,Niloofar Eslahi,S. Hajir Bahrami,Shahram Rabbani 한국섬유공학회 2021 Fibers and polymers Vol.22 No.5

        In this study, bulk and non-bulk electrospun scaffolds from polycaprolactone (PCL) containing graphene oxide(GO) were fabricated. Graphene oxide with 0.3, 0.5, and 1 wt% was added to different concentrations of PCL solutions undersonication. The blends were electrospun under varied conditions of 10-20 kV applied voltages, a distance of 10 to 20 cm, anda 0.5 ml/hr flow rate. The web of PCL(10 %)-GO(0.5 %) was selected as an optimum one via scanning electron microscopy(SEM) images, which exhibited uniform morphology with a 257±18 nm average diameter. The fourier transform infrared(FTIR) results showed that the specified peaks of both PCL and GO in the blends. Mechanical investigation exhibited higherstrength of the PCL-GO web (about 4.3 MPa) compare to the PCL web. The porosity of the webs was measured bydensitometry, which showed an increase in porosity from 80 % to 92 % after the bulking process (ultra-sonication, followedby freeze-drying). The MTT assay was employed using human adipose-derived mesenchymal stem cells (hAMSCs) on thescaffolds. Results indicated that the cell viability of bulk and non-bulk PCL-GO scaffolds were about 98 % and 99.8 %,respectively. In vivo study was carried out on defected cartilage knees of fourteen New Zealand rabbits. For monitoring thecartilage repair, magnetic resonance imaging (MRI) as well as pathological investigations were performed after surgery. Theresults of MRI and H&E staining showed high qualified healing of defects, which were exposed to bulk nanofibrous scaffold. Therefore, bulk PCL-GO electrospun scaffolds can be introduced as a suitable scaffolds for cartilage regeneration.

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        Effect of Vanilla as a Natural Alternative to Traditional Carriers in Polyester Dyeing with Disperse Dyes

        Sara Jalali,Reihaneh Rezaei,Mansoureh Ghanbar Afjeh,Niloofar Eslahi 한국섬유공학회 2019 Fibers and polymers Vol.20 No.1

        In this work, a new natural-based approach was exploited to improve the low temperature carrier method in dyeing process of polyester fabrics. Vanilla was introduced as an alternative substitute for commercial toxic carriers including CTM and Levegal PEW in particular. With use of vanilla in dyeing process, the dye uptake of PET fabrics dyed with C.I. Disperse blue 56 and C.I. Disperse Red 1 was increased significantly. In order to have an economical dyeing process, a two-component mixture of carrier and vanilla was assessed to reduce the consumption of carrier (1/6 of optimum amount) and vanilla. The results showed that vanilla and commercial carriers were compatible and so their mixtures led to higher dye uptake compared to each one individually. The study confirmed that vanilla as an eco-friendly material could substitute the use of commercial carriers in polyester dyeing and led to excellent wash, rub, and better light fastness properties.

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