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RISS 인기검색어
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- 저자 : Nandakumar Kalarikkal (검색결과 1 건)
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Robin Augustine,Sabu Thomas,Nandakumar Kalarikkal 한국조직공학과 재생의학회 2015 조직공학과 재생의학 Vol.12 No.1
Barrier property of materials to microbes is an important aspect in many applications like wound dressingsand skin substitutes. Lack of a standard method for the evaluation of microbial barrier property limits the considerationof this important aspect by many bioengineers and biomaterial scientists. Thus, in this study we areintended to develop a standard method for the quantitative assessment of Microbial Barrier Property (MBP) andexpress this in terms of percentage in comparison with a control which resembles a bare wound or a standard existingwound coverage material. In this study, we have evaluated the microbial barrier property of electrospun materialswith different pore spaces and our study showed that this method can be successfully used for the assessment of bacterialbarrier property of materials intended for wound dressing and skin substitute applications. Further, the resultsshowed that the MBP will vary with the test conditions. This methodology can be used to measure the microbialbarrier property of wide range of materials like skin substitute materials, wound dressings, medical textiles and manyother materials where microbial prevention is important. This methodology can also be extended to the specificdetermination of bacterial, fungal or viral barrier property with minor modifications.
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