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Miner, Thomas D. 이화여자대학교 사범대학 과학교육과 1968 과학교육 Vol.4 No.-
방사능의 위험으로부터의 학생들의 보호는 과학 교사들에 대한 여분의 책임이 되지만 매우 단순한 예비 조치가 가장 적은 피해를 가져온다는 것이 강조되어야 한다. 새로운 NCRP 사전은 위험성과 조절에 대한 특별한 자료를 포함하고 있다. 그 제안들을 따름으로써 교사들은 교실에서의 방사능 피해를 최소한으로 할수있다. 그렇다고 과학교사는 그의 학과 과정에서 방사능 현상에 관한 중요한 연구를 제거해서는 안된다. 이 번역을 도와주신 정명숙 선생님께 감사를드립니다.
Lymphopenia following pancreaticoduodenectomy is associated with pancreatic fistula formation
Joshua T. Cohen,Kevin P. Charpentier,Thomas J. Miner,William G. Cioffi,Rachel E. Beard 한국간담췌외과학회 2021 Annals of hepato-biliary-pancreatic surgery Vol.25 No.2
Backgrounds/Aims: Post-operative pancreatic fistulas (POPF) are a major source of morbidity following pancreaticoduodenectomy (PD). This study aims to investigate if persistent lymphopenia, a known marker of sepsis, can act as an additional marker of POPF with clinical implications that could help direct drain management. Methods: A retrospective chart review of all patients who underwent PD in a single hospital network from 2008 to 2018. Persistent lymphopenia was defined as lymphopenia beyond post-operative day #3. Results: Of the 201 patients who underwent PD during the study period 161 patients had relevant laboratory data, 81 of whom had persistent lymphopenia. 17 patients with persistent lymphopenia went on to develop a POPF, compared to 7 patients without. Persistent lymphopenia had a negative predictive value of 91.3%. Multivariate analysis revealed only persistent lymphopenia as being independently associated with POPF (HR 2.57, 95% CI 1.07-6.643, p=0.039). Patients with persistent lymphopenia were more likely to have a complication requiring intervention (56.8% vs 35.0%, p<0.001). Conclusions: Persistent lymphopenia is a readily available early marker of POPF that holds the potential to identify clinically relevant POPF in patients where no surgical drain is present, and to act as an adjunct of drain amylase helping to guide drain management.