http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Manoharan, Koildhasan (검색결과 143 건)
- 무료
- 기관 내 무료
- 유료
-
-
Manoharan Premkumar,Rameshkumar Sumithira 전력전자학회 2018 JOURNAL OF POWER ELECTRONICS Vol.18 No.6
This paper proposes a novel hybrid maximum power point tracking (MPPT) algorithm combining a Whale Optimization Algorithm (WOA) and the conventional Perturb & Observation (P&O) to track/extract the highest amount of power from a solar photovoltaic (SPV) system working under partial shading conditions (PSCs). The proposed hybrid algorithm is based on a WOA which predicts the initial global peak (GP) and is followed by P&O in the final stage to achieve a quicker convergence to a GP. Thus, this hybrid algorithm overcomes the computational burden encountered in a standalone WOA, grey wolf optimization (GWO) and hybrid GWO reported in the literature. The conventional algorithm searches for the maximum power point (MPP) in the predicted region by the WOA. The proposed MPPT technique is modelled and simulated using MATLAB/Simulink for simulating an environment to check its effectiveness in accurately tracking the MPP during the GP region. This hybrid algorithm is compared with a standalone WOA, GWO and hybrid GWO. From the simulating results, it is shown that the proposed algorithm offers high tracking performance and that it increases the output power level of a SPV system under partial shading. The algorithm also verified experimentally on various PSCs.
-
Manoharan Kiruthiga,Raguru Pandu Kumudini Devi,Periasamy Somasundaram 대한전기학회 2022 Journal of Electrical Engineering & Technology Vol.17 No.4
This paper demonstrates the impact of Static Synchronous Compensator (STATCOM) on generator loss of excitation protection. Presence of Static Synchronous Compensator (STATCOM) in transmission line aff ects the reach/operating time of generator loss of excitation protection relay depending upon the loading conditions. In this context hardware in the loop simulation by using real time digital simulator (RT-Lab), linear power amplifi er and generator protection relay (MiCom P343) is performed to analyze the impact of Static Synchronous Compensator (STATCOM) on reach of loss of excitation protection relay. The hardware in the loop simulation is performed for total loss of excitation and partial loss of excitation. The obtained result clearly demonstrates that there is a delay in operating time of relay in the presence of Static Synchronous Compensator (STATCOM). The delay in operating time aff ects the coordination between loss of excitation protection, generator under excitation limiter and steady state stability limit
-
Role of adhesion in shear strength of nanowire–substrate interfaces
Manoharan, M P,Haque, M A Institute of Physics [etc.] 2009 Journal of Physics. D, Applied Physics Vol.42 No.9
<P>The shear strength of nanowire–substrate contact critically influences the electrical and mechanical contact characteristics of nanowire-based sensors, actuators and nanoelectronic devices. Yet, very few studies are available in the literature because of the experimental challenges associated with these one-dimensional nanostructures and none of the existing contact mechanics models account for their ultra-high bending compliance. Using a novel experimental setup that effectively decouples adhesion and friction forces, we show that the friction coefficient for the zinc oxide nanowires and silicon system can be about two orders of magnitude higher than the bulk values, even under zero externally applied normal loads. We model nanowire bending compliance and capillary line tension as competing mechanisms to explain the observed anomalous adhesion–friction coupling and establish a criterion for contact area dependence in friction in one-dimensional interfaces.</P>
-
Manoharan, Ranjith Kumar,Lee, Jin‐,Hyung,Lee, Jintae John Wiley and Sons Inc. 2018 Microbial biotechnology Vol.11 No.6
<P><B>Summary</B></P><P>Certain pathogenic bacteria and yeast form biofilms on biotic and abiotic surfaces including medical devices and implants. Hence, the development of antibiofilm coating materials becomes relevant. The virulence of those colonizing pathogens can be reduced by inhibiting biofilm formation rather than killing pathogens using excessive amounts of antimicrobials, which is touted as one of the main reasons for the development of drug resistance. <I>Candida albicans</I> is an opportunistic fungal pathogen, and the transition of yeast cells to hyphal cells is believed to be a crucial virulence factor. Previous studies have shown that indole and its derivatives possess antivirulence properties against various bacterial pathogens. In this study, we used various indole derivatives to investigate biofilm‐inhibiting activity against <I>C. albicans</I>. Our study revealed that 7‐benzyloxyindole, 4‐fluoroindole and 5‐iodoindole effectively inhibited biofilm formation compared to the antifungal agent fluconazole. Particularly, 7‐benzyloxyindole at 0.02 mM (4.5 μg ml<SUP>−1</SUP>) significantly reduced <I>C. albicans</I> biofilm formation, but had no effect on planktonic cells, and this finding was confirmed by a 2,3‐bis‐(2‐methoxy‐4‐nitro‐5‐sulfophenyl)‐2H‐tetrazolium‐5‐carboxanilide (XTT) assay and three‐dimensional confocal laser scanning microscopy. Scanning electron microscopy analyses revealed that 7‐benzyloxyindole effectively inhibited hyphal formation, which explains biofilm inhibition. Transcriptomic analysis showed that 7‐benzyloxyindole downregulated the expressions of several hypha/biofilm‐related genes (<I>ALS3</I>,<I>ECE1</I>,<I>HWP1</I> and <I>RBT1</I>). A <I>C. albicans</I>‐infected <I>Caenorhabditis elegans</I> model system was used to confirm the antivirulence efficacy of 7‐benzyloxyindole.</P>
-
Manoharan, S.,Palanimuthu, D.,Baskaran, N.,Silvan, S. Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.11
Apoptosis, also known as cell suicide or programmed cell death, removes unwanted and genetically damaged cells from the body. Evasion of apoptosis is one of the major characteristic features of rapidly proliferating tumor cells. Chemopreventive agents inhibit or suppress tumor formation through apoptotic induction in target tissues. The aim of the present study was to investigate the pro-apoptotic potential of lupeol during 7,12-dimethylbenz(a) anthracene (DMBA) induced hamster buccal pouch carcinogenesis. Topical application of 0.5% DMBA three times a week for 14 weeks in the buccal pouches of golden Syrian hamsters resulted in oral squamous cell carcinoma. The expression pattern of apoptotic markers was analyzed using immunohistochemistry (p53, Bcl-2, Bax) and ELISA reader (caspase 3 and 9). In the present study, 100% tumor formation with defects in apoptotic markerexpression pattern was noticed in hamsters treated with DMBA alone. Oral administration of lupeol at a dose of 50mg/kg bw completely prevented the formation oral tumors as well as decreased the expression p53 and Bcl-2, while increasing the expression of Bax and the activities of caspase 3 and 9. The present study thus indicated that lupeol might inhibit DMBA-induced oral tumor formation through its pro-apoptotic potential in golden Syrian hamsters.
-
Manoharan, Mohana Sundar,Ahmed, Ashraf,Park, Joung-Hu The Korean Institute of Power Electronics 2017 JOURNAL OF POWER ELECTRONICS Vol.17 No.1
In this paper, a new architecture for a cost-effective power conditioning systems (PCS) using a single-sourced asymmetric cascaded H-bridge multilevel inverter (MLI) for photovoltaic (PV) applications is proposed. The asymmetric MLI topology has a reduced number of parts compared to the symmetrical type for the same number of voltage level. However, the modulation index threshold related to the drop in the number of levels of the inverter output is higher than that of the symmetrical MLI. This problem results in a modulation index limitation which is relatively higher than that of the symmetrical MLI. Hence, an extra voltage pre-regulator becomes a necessary component in the PCS under a wide operating bias variation. In addition to pre-stage voltage regulation for the constant MLI dc-links, another auxiliary pre-regulator should provide isolation and voltage balance among the multiple H-bridge cells in the asymmetrical MLI as well as the symmetrical ones. The proposed PCS uses a single-ended DC-DC converter topology with a coupled inductor and charge-pump circuit to satisfy all of the aforementioned requirements. Since the proposed integrated-type voltage pre-regulator circuit uses only a single MOSFET switch and a single magnetic component, the size and cost of the PCS is an optimal trade-off. In addition, the voltage balance between the separate H-bridge cells is automatically maintained by the number of turns in the coupled inductor transformer regardless of the duty cycle, which eliminates the need for an extra voltage regulator for the auxiliary H-bridge in MLIs. The voltage balance is also maintained under the discontinuous conduction mode (DCM). Thus, the PCS is also operational during light load conditions. The proposed architecture can apply the module-integrated converter (MIC) concept to perform distributed MPPT. The proposed architecture is analyzed and verified for a 7-level asymmetric MLI, using simulation results and a hardware implementation.
-
Manoharan, Ravi,Seong, Hyun-A,Ha, Hyunjung Hindawi 2018 Oxidative medicine and cellular longevity Vol.2018 No.-
<P>Serine-threonine kinase receptor-associated protein (STRAP) is a transforming growth factor <I>β</I> (TGF-<I>β</I>) receptor-interacting protein that has been implicated in both cell proliferation and cell death in response to various stresses. However, the precise roles of STRAP in these cellular processes are still unclear. The mechanisms by which STRAP controls both cell proliferation and cell death are now beginning to be unraveled. In addition to its biological roles, this review also focuses on the dual functions of STRAP in cancers displaying redox dysregulation, where it can behave as a tumor suppressor or an oncogene (i.e., it can either inhibit or promote tumor formation), depending on the cellular context. Further studies are needed to define the functions of STRAP and the redox-sensitive intracellular signaling pathways that enhance either cell proliferation or cell death in human cancer tissues, which may help in the development of effective treatments for cancer.</P>
-
Manoharan, Ranjith Kumar,Shanmugam, Ashokraj,Hwang, Indeok,Park, Jong-In,Nou, Ill-Sup,Scoles, G.J. Canadian Science Publishing 2016 Genome Vol.59 No.6
<P> Brassica oleracea var. capitata (cabbage) is an important vegetable crop in Asian countries such as Korea, China, and Japan. Cabbage production is severely affected by clubroot disease caused by the soil-borne plant pathogen Plasmodiophora brassicae. During clubroot development, methyl salicylate (MeSA) is biosynthesized from salicylic acid (SA) by methyltransferase. In addition, methyl salicylate esterase (MES) plays a major role in the conversion of MeSA back into free SA. The interrelationship between MES and methytransferases during clubroot development has not been fully explored. To begin to examine these relationships, we investigated the expression of MES genes in disease-susceptible and disease-resistant plants during clubroot development. We identified three MES-encoding genes potentially involved in the defense against pathogen attack. We found that SS1 was upregulated in both the leaves and roots of B. oleracea during P. brassicae infection. These results support the conclusion that SA biosynthesis is suppressed during pathogen infection in resistant plants. We also characterized the expression of a B. oleracea BSMT gene, which appears to be involved in glycosylation rather than MeSA biosynthesis. Our results provide insight into the functions and interactions of genes for MES and methyltransferase during infection. Taken together, our findings indicate that MES genes are important candidates for use to control clubroot diseases. </P>
-
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
