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MANCHESTER R. N. The Korean Astronomical Society 1996 Journal of The Korean Astronomical Society Vol.29 No.suppl1
Recent surveys at Parkes, in particular the 70 cm survey of the southern sky, have discovered many pulsars, including 17 miilisecond pulsars in the Galactic disk. Timing and polarization observations of some of these pulsars are described. The only two pulsars known to be in orbit around massive non-degenerate stellar compamons were also discovered at Parkes, and some recent observational results for these pulsars are also presented.
Becoming the Broadest-caster: The Regulatory Hurdles of Canada’s Radio Deal of the Decade
Pierre C. Bélanger(Pierre C. Bélanger ),Geoffrey Manchester(Geoffrey Manchester ) 한국캐나다학회 2013 Asia-Pacific Journal of Canadian Studies (APJCS) Vol.19 No.2
In July 2013 The Canadian Radio-Television and Telecommunications Commission (CRTC) approved an unprecedented merger between Bell Canada Enterprises (Bell Media) and Astral Media. Bell Media, a telecommunications giant, bought Astral’s radio, television and outdoor advertising properties for $3.8 Billion (CAD) in Canada’s largest ever purchase of legacy media by any company. To meet strict ownership regulations Bell Media would auction ten popular English radio stations while gaining several new stations in French speaking Canada from Astral, a key motivation behind the takeover strategy. The deal met plenty of resistance, first from incumbent broadcasters and eventually by the CRTC, who shut down Bell Media’s first application on the grounds that the transaction was not in the interest of Canadians. Bell Media significantly restructured their second proposal to include substantial benefits to Canadian radio and the broadcasting industry as a whole, pleasing both regulators. The merger confirms the coveted position that traditional content represents in a highly unstable and unpredictable digital media environment.
하구에서 지질, 플랑크톤, 어류의 PCB 축적 유형에 대한 ortho-위치 치환의 영향
WILLMAN, ERIC J.,ARMSTRONG, DAVID E.,MANCHESTER-NEESVIG, JON B. 慶星大學校 環境問題硏究所 1997 環境硏報 Vol.7 No.1
수중의 먹이사슬에서 non-, mono-ortho(동일 평면적 구조의)PCB 이성질체(congener)군의 축적은 다이옥신같은 독성 때문에 특별한 관심거리이다. 게다가 큰 ortho-치환을 가진 동족체(homologs)들보다 더 높은 옥탄올-물 분배계수가 동일 평면적 구조의 이성지체(congener)의 선택적인 축적에 대한 가능성을 제안한다. 우리는 전통적이고 다차원의 전자호획검출기를 가진 가스크로마토그래피를 사용하여 Green만(灣), WI의 어류, 플랑크톤, 저질로부터 여섯가지 동족체(homologs)군에서 0-3 ortho-chlorine를 포함하는 47개의 PCB 이성질체(congener)들이 많아지게 되는 반면에 trichloro 이성질체(congener)는 감소되었다. trichloro 이성질체(congener)는 감소되는 동안 저질에서 플랑크톤과 어류에 이르는 생태계에서 높은 수준으로 이동되는 PCBs처럼 같은 동족체(homologs)들 또한 많아지게 되었다. 대부분 독성(다이옥신 같은)이성질체(congener)의 많아지는 유형은 또한 주로 총 염소 치환에 의해 영향을 받게 되었다; ortho-치환의 정도는 조직적으로 플랑크톤과 어류에서의 축적에 영향을 주지는 않았다.
Tan, Dun-Xian,Zheng, Xiaodong,Kong, Jin,Manchester, Lucien C.,Hardeland, Ruediger,Kim, Seok Joong,Xu, Xiaoying,Reiter, Russel J. MDPI 2014 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.15 No.9
<P>Melatonin and melatonin isomers exist and/or coexist in living organisms including yeasts, bacteria and plants. The levels of melatonin isomers are significantly higher than that of melatonin in some plants and in several fermented products such as in wine and bread. Currently, there are no reports documenting the presence of melatonin isomers in vertebrates. From an evolutionary point of view, it is unlikely that melatonin isomers do not exist in vertebrates. On the other hand, large quantities of the microbial flora exist in the gut of the vertebrates. These microorganisms frequently exchange materials with the host. Melatonin isomers, which are produced by these organisms inevitably enter the host’s system. The origins of melatonin and its isomers can be traced back to photosynthetic bacteria and other primitive unicellular organisms. Since some of these bacteria are believed to be the precursors of mitochondria and chloroplasts these cellular organelles may be the primary sites of melatonin production in animals or in plants, respectively. Phylogenic analysis based on its rate-limiting synthetic enzyme, serotonin <I>N</I>-acetyltransferase (SNAT), indicates its multiple origins during evolution. Therefore, it is likely that melatonin and its isomer are also present in the domain of archaea, which perhaps require these molecules to protect them against hostile environments including extremely high or low temperature. Evidence indicates that the initial and primary function of melatonin and its isomers was to serve as the first-line of defence against oxidative stress and all other functions were acquired during evolution either by the process of adoption or by the extension of its antioxidative capacity.</P>
Thomas H. Reynolds Ⅳ,Pak, Yun-Bae,Thurl E. Harris,Jill Manchester,Eugene J. Barrett,John C. Lawrence, Jr. Plant molecular biology and biotechnology research 2005 Plant molecular biology and biotechnology research Vol.2005 No.
UDP-glucose (UDP-Gle) and glycogen levels in skeletal muscle fibers of defined fiber type were measured using microanalytical methods. Infusing rats with insulin increased glycogen in both Type I and Type II fibers Insulin was without effect in UDP-Gle in TypeⅠfibers but decreased UDP-Gle by 35-40% in Type IIA/D and Type IIB fibers. The reduction in UDP-Gle suggested that UDP-Gle pyrophosphorylase (PPL) activity might limit glycogen synthesis in response to insulin. To explore this possibility, we generated mice overexpressing a UDP-Glc PPL, transgene in skeletal muscle. The transgene increased both UDP-Glc PPL activity and levels of UDP-Glc in skeletal muscles by 3-fold. However, overexpression of UDP-Glc PPL was without effect on either the levels of skeletal muscle glycogen or glucose tolerance in vivo. The transgene was also without effect on either control or insulin-stimulated rates of C-glucose incorporation into glycogen in muscles incubated in vitro. The results indicate that UDP-Glc PPL activity is not limiting for glycogen synthesis
Reynolds IV, Thomas H.,Pak, Yunbae,Harris, Thurl E.,Manchester, Jill,Barrett, Eugene J.,Lawrence Jr., John C. American Society for Biochemistry and Molecular Bi 2005 The Journal of biological chemistry Vol.280 No.7
<P>UDP-glucose (UDP-Glc) and glycogen levels in skeletal muscle fibers of defined fiber type were measured using microanalytical methods. Infusing rats with insulin increased glycogen in both Type I and Type II fibers. Insulin was without effect on UDP-Glc in Type I fibers but decreased UDP-Glc by 35-40% in Type IIA/D and Type IIB fibers. The reduction in UDP-Glc suggested that UDP-Glc pyrophosphorylase (PPL) activity might limit glycogen synthesis in response to insulin. To explore this possibility, we generated mice overexpressing a UDP-Glc PPL transgene in skeletal muscle. The transgene increased both UDP-Glc PPL activity and levels of UDP-Glc in skeletal muscles by approximately 3-fold. However, overexpression of UDP-Glc PPL was without effect on either the levels of skeletal muscle glycogen or glucose tolerance in vivo. The transgene was also without effect on either control or insulin-stimulated rates of (14)C-glucose incorporation into glycogen in muscles incubated in vitro. The results indicate that UDP-Glc PPL activity is not limiting for glycogen synthesis.</P>