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과학기술 분야 표준 서지 용어 개발
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Status of Rheumatology in Spain in 2017: 2.0 Rheumatologists per 100 000 Population
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ScienceDMZ 기반의 네트워크 구성에서 접근제어정책 적용
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Evaluation of First-Draw Whole Blood^ Point-of-Care Cardiac Markers in the Context of the Universal Definition of Myocardial Infarction: A Comparison of a Multimarker Panel to Troponin Alone and to Testing in the Central Laboratory
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The death of Daphnis
- 검색키워드
- 저자 : Maha M. Hassan (검색결과 4 건)
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Behavior of concrete-filled double skin steel tube beam-columns
Maha M. Hassan,Ahmed A. Mahmoud,Mohammed H. Serror 국제구조공학회 2016 Steel and Composite Structures, An International J Vol.22 No.5
Concrete-filled double skin steel tube (CFDST) beam-columns are widely used in industrial plants, subways, high-rise buildings and arch bridges. The CFDST columns have the same advantages as traditional CFT members. Moreover, they have lighter weight, higher bending stiffness, better cyclic performance, and have higher fire resistance capacities than their CFT counterparts. The scope of this study is to develop finite element models that can predict accepted capacities of double skin concrete-filled tube columns under the combined effect of axial and bending actions. The analysis results were studied to determine the distribution of stresses among the different components and the effect of the concrete core on the outer and inner steel tube. The developed models are first verified against the available experimental data. Accordingly, an extensive parametric study was performed considering different key factors including load eccentricity, slenderness ratio, concrete compressive strength, and steel tube yield strength. The results of the performed parametric study are intended to supplement the experimental research and examine the accuracy of the available design formulas.
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Oleuropein Induces Anti-metastatic Effects in Breast Cancer
Hassan, Zeinab K.,Elamin, Maha H.,Daghestani, Maha H.,Omer, Sawsan A.,Al-Olayan, Ebtesam M.,Elobeid, Mai A.,Virk, Promy,Mohammed, Osama B. Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.9
Breast cancer causes death due to distant metastases in which tumor cells produce matrix metalloproteinase (MMP) enzymes which facilitate invasion. Oleuropein, the main olive oil polyphenol, has anti-proliferative effects. This study aimed to investigate the effect of oleuropein on the metastatic and anti-metastatic gene expression in the MDA human breast cancer cell line. We evaluated the MMPs and TIMPs gene expression by semi-quantitative reverse transcriptase polymerase chain reaction (RT-PCR) in treated and untreated cells. This study demonstrated that OL may induce anti-metastatic effects on human breast cancer cells. We found that TIMP1,-3, and -4 were over-expressed after all periods of incubation in treated cancer cells compared to untreated cells, while MMP2 and MMP9 genes were down-regulated, at least initially. Treatment of breast cancer cells with oleuropein could help in prevention of cancer metastasis by increasing the TIMPs and suppressing the MMPs gene expressions.
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Convalescent plasma in COVID-19: renewed focus on the timing and effectiveness of an old therapy
Hebat-Allah Hassan Nashaat,Maha Anani,Fadia M. Attia 대한혈액학회 2022 Blood Research Vol.57 No.1
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the coronavirus disease 2019 (COVID-19) pandemic that has strained health care systems worldwide and resulted in high mortality. The current COVID-19 treatment is based on supportive and symptomatic care. Therefore, convalescent plasma (CP), which provides passive immunization against many infectious diseases, has been studied for COVID-19 management. To date, a large number of randomized and non-randomized clinical trials as well as many systematic reviews have revealed conflicting results. This article summarizes the basic principles of passive immunization, particularly addressing CP in COVID-19. It also evaluates the effectiveness of CP as a therapy in patients with COVID-19, clinical trial reports and systematic reviews, regulatory considerations and different protocols that are authorized in different countries to use it safely and effectively. An advanced search was carried out in major databases (PubMed, Cochrane Library, and MEDLINE) and Google Scholar using the following key words: SARS-CoV-2, COVID-19, convalescent plasma, and the applied query was “convalescent plasma” AND “COVID-19 OR SARS-CoV-2”. The results were filtered and duplicate data were removed. Collective evidence indicates that two cardinal players determine the effectiveness of CP use, time of infusion, and quality of CP. Early administration of CP with high neutralizing anti-spike IgG titer is hypothesized to be effective in improving clinical outcome, prevent progression, decrease the length of hospital stay, and reduce mortality. However, more reliable, high quality, well-controlled, double-blinded, randomized, international and multicenter collaborative trials are still needed.
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Parametric study of shear strength of CFRP strengthened end-web panels
Haitham A. Shalaby,Maha M. Hassan,Sherif S. Safar 국제구조공학회 2019 Steel and Composite Structures, An International J Vol.31 No.2
Strengthening of civil infrastructure with advanced composites have recently become one of the most popular methods. The use of Fiber Reinforced Polymer (FRP) strips plates and fabric for strengthening of reinforced concrete structures has well established design guidelines and standards. Research on the application of FRP composites to steel structures compared to concrete structures is limited, especially for shear strengthening applications. Whereas, there is a need for cost-effective system that could be used to strengthen steel high-way bridge girders to cope with losses due to corrosion in addition to continuous demands for increasing traffic loads. In this study, a parametric finite element study is performed to investigate the effect of applying thick CFRP strips diagonally on webs of plate girders on the shear strength of end-web panels. The study focuses on illustrating the effect of several geometric parameters on nominal shear strength. Hence, a formula is developed to determine the enhancement of shear strength gained upon the application of CFRP strips.
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