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        Capsule enteroscopy versus small-bowel ultrasonography for the detection and differential diagnosis of intestinal diseases

        Luca Elli,Erica Centorrino,Andrea Costantino,Maurizio Vecchi,Stefania Orlando,Mirella Fraquelli 대한소화기내시경학회 2022 Clinical Endoscopy Vol.55 No.4

        Background/Aims: Capsule enteroscopy (CE) and intestinal ultrasonography (IUS) are techniques that are currently used for investigatingsmall-bowel (SB) diseases. The aim of this study was to compare the main imaging findings and the lesion detection rate (LDR)of CE and IUS in different clinical scenarios involving the SB. Methods: We retrospectively enrolled patients who underwent CE and IUS for obscure gastrointestinal bleeding (OGIB), complicatedceliac disease (CeD), and suspected or known inflammatory bowel disease (IBD). We evaluated the LDR of both techniques. The accuracyof IUS was determined using CE as the reference standard. Results: A total of 159 patients (113 female; mean age, 49±19 years) were enrolled. The LDR was 55% and 33% for CE and IUS(p<0.05), respectively. Subgroup analysis showed that the LDR of CE was significantly higher than that of IUS in patients with OGIB(62% vs. 14%, p<0.05) and CeD (55% vs. 35%, p<0.05). IUS showed a similar LDR to CE in patients with suspected or known IBD (51%vs. 46%, p=0.83). Conclusions: CE should be preferred in cases of OGIB and CeD, whereas IUS should be considered an early step in the diagnosis andfollow-up of IBD even in patients with a proximal SB localization of the disease.

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