http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Biomolecule-embedded metal-organic frameworks as an innovative sensing platform
Kempahanumakkagari, Sureshkumar,Kumar, Vanish,Samaddar, Pallabi,Kumar, Pawan,Ramakrishnappa, Thippeswamy,Kim, Ki-Hyun Elsevier 2018 BIOTECHNOLOGY ADVANCES Vol.36 No.2
<P><B>Abstract</B></P> <P>Technological advancements combined with materials research have led to the generation of enormous types of novel substrates and materials for use in various biological/medical, energy, and environmental applications. Lately, the embedding of biomolecules in novel and/or advanced materials (e.g., metal-organic frameworks (MOFs), nanoparticles, hydrogels, graphene, and their hybrid composites) has become a vital research area in the construction of an innovative platform for various applications including sensors (or biosensors), biofuel cells, and bioelectronic devices. Due to the intriguing properties of MOFs (e.g., framework architecture, topology, and optical properties), they have contributed considerably to recent progresses in enzymatic catalysis, antibody-antigen interactions, or many other related approaches. Here, we aim to describe the different strategies for the design and synthesis of diverse biomolecule-embedded MOFs for various sensing (e.g., optical, electrochemical, biological, and miscellaneous) techniques. Additionally, the benefits and future prospective of MOFs-based biomolecular immobilization as an innovative sensing platform are discussed along with the evaluation on their performance to seek for further development in this emerging research area.</P>
Metal–organic framework composites as electrocatalysts for electrochemical sensing applications
Kempahanumakkagari, Sureshkumar,Vellingiri, Kowsalya,Deep, Akash,Kwon, Eilhann E.,Bolan, Nanthi,Kim, Ki-Hyun Elsevier 2018 Coordination chemistry reviews Vol.357 No.-
<P><B>Abstract</B></P> <P>Metal–organic frameworks (MOFs) are porous coordination polymers linked by metal ions and ligands. With the progress of MOF research, many redox active MOFs have been synthesized by judicious selection of the electroactive metal ions and/or organic functional groups. Due to the unique properties (e.g., high surface areas, tailorable pore sizes, and exposed active sites), MOFs are found to have a wide range of redox activities to be applied in various fields (e.g., microporous conductors, electrocatalysts, energy storage devices, and electrochemical sensors). The potential of the MOFs composites has also been realized as ideal hosts for functional materials (like conducting nanoparticles). These composites are thus demonstrated to have superior electrocatalytic/electrochemical sensing properties than their pristine forms. Accordingly, various MOF composite-based platforms have been developed as efficient electrochemical sensors for environmental and biochemical targets. This review was organized to provide up-to-date information and insights into the fundamental aspects of MOF composites as electrocatalytic/electrochemical sensors.</P> <P><B>Highlights</B></P> <P> <UL> <LI> MOF composites have been developed with superior electrocatalytic properties. </LI> <LI> MOF composites can be applied as electrocatalysts for electrochemical sensing. </LI> <LI> They were employed for sensing environmental analytes like metals and organics. </LI> <LI> Their use was extended further to detect various biological targets like glucose. </LI> </UL> </P>
Nanomaterial-based electrochemical sensors for arsenic - A review
Kempahanumakkagari, Sureshkumar,Deep, Akash,Kim, Ki-Hyun,Kumar Kailasa, Suresh,Yoon, Hye-On Elsevier Applied Science 2017 Biosensors & Bioelectronics Vol. No.
<P><B>Abstract</B></P> <P>The existence of arsenic in the environment poses severe global health threats. Considering its toxicity, the sensing of arsenic is extremely important. Due to the complexity of environmental and biological samples, many of the available detection methods for arsenic have serious limitations on selectivity and sensitivity. To improve sensitivity and selectivity and to circumvent interferences, different electrode systems have been developed based on surface modification with nanomaterials including carbonaceous nanomaterials, metallic nanoparticles (MNPs), metal nanotubes (MNTs), and even enzymes. Despite the progress made in electrochemical sensing of arsenic, some issues still need to be addressed to realize cost effective, portable, and flow-injection type sensor systems. The present review provides an in-depth evaluation of the nanoparticle-modified electrode (NME) based methods for the electrochemical sensing of arsenic. NME based sensing systems are projected to become an important option for monitoring hazardous pollutants in both environmental and biological media.</P> <P><B>Highlights</B></P> <P> <UL> <LI> About 140 million people inadvertently consume groundwater containing high levels of As. </LI> <LI> Sensitive and selective analysis of As is of high importance to identify the contaminated source. </LI> <LI> This review summarizes nanomaterial-modified electrode interfaces for sensing inorganic As. </LI> <LI> The use of nanoparticle-modified electrodes are set to meet the commercial challenges. </LI> <LI> It is desirable to develop cost effective, field portable, and highly selective sensors to monitor As. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>Various types of nanoparticles used in electrode modification for electrochemical sensing applications toward arsenic</P> <P>[DISPLAY OMISSION]</P>