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Michiaki TOYODA,Kazuhisa OBA,Tetsuya YANAGIMOTO,Takatomo MORI,Kazuo HEMMI 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8
In this paper, we propose a method to update numeral template images according to the width of characters for holistic matching. The purpose of our study is to develop a method that discriminates between correct patterns and incorrect patterns by matching input images against template images. We applied this method to handwritten class marks of book labels to assist librarians in Japanese libraries to find misshelved books. In experiments, initial numeral template images are gathered randomly from isolated characters. We confirmed that the proposed method is useful to increase the variation of the width of template images.
조규영,Nakamura Akinobu,Oba-Yamamoto Chiho,Tsuchida Kazuhisa,Yanagiya Shingo,Manda Naoki,Kurihara Yoshio,Aoki Shin,Atsumi Tatsuya,Miyoshi Hideaki 대한당뇨병학회 2020 Diabetes and Metabolism Journal Vol.44 No.4
Background: To explore the efficacy and safety of switching from once-daily basal insulin therapy to once-daily pre-meal injection insulin degludec/insulin aspart (IDegAsp) with respect to the glycemic control of participants with type 2 diabetes mellitus (T2DM). Methods: In this multicenter, open-label, prospective, randomized, parallel-group comparison trial, participants on basal insulin therapy were switched to IDegAsp (IDegAsp group; n=30) or continued basal insulin (Basal group; n=29). The primary endpoint was the superiority of IDegAsp in causing changes in the daily blood glucose profile, especially post-prandial blood glucose concentration after 12 weeks. Results: Blood glucose concentrations after dinner and before bedtime were lower in the IDegAsp group, and the improvement in blood glucose before bedtime was significantly greater in the IDegAsp group than in the Basal group at 12 weeks (−1.7±3.0 mmol/L vs. 0.3±2.1 mmol/L, P<0.05). Intriguingly, glycemic control after breakfast was not improved by IDegAsp injection before breakfast, in contrast to the favorable effect of injection before dinner on blood glucose after dinner. Glycosylated hemoglobin significantly decreased only in the IDegAsp group (58 to 55 mmol/mol, P<0.05). Changes in daily insulin dose, body mass, and recorded adverse effects, including hypoglycemia, were comparable between groups. Conclusion: IDegAsp was more effective than basal insulin at reducing blood glucose after dinner and before bedtime, but did not increase the incidence of hypoglycemia. Switching from basal insulin to IDegAsp does not increase the burden on the patient and positively impacts glycemic control in patients with T2DM.