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Fatty acids fouling on forward osmosis membrane: impact of pH
Ruengruehan, K.,Kim, H.,Hai Yen, L.T.,Jang, A.,Lee, W.,Kang, S. Balaban Publishers 2016 Desalination and Water Treatment Vol.57 No.16
<P>The fouling propensity of the fatty acids is investigated during the operation of the osmotically driven membrane process. Experiments were performed at various pH values ranged from 4.0 to 9.0 in the presence of the octanoic acid as the model fatty acids. Results demonstrated that the fatty acid fouling was significantly dependent on the changes of pH. In all tested pH values, permeate flux was sharply decreased during the initial coverage of fatty acids on the membrane surface, then slowly decreased as the fatty acid layer became developed. At pH 9.0, fouling propensity was less than those of pH values around 4.9 (pK(a) of octanoic acid) due to the protonation of the carboxylic group of octanoic acid molecules, which resulted in electrostatic repulsion between octanoic acid molecules and membrane surfaces. The measurement of contact angle and FTIR spectra also supports that more octanoic acid molecules are adsorbed on FO membrane surfaces at the low pH than at the high pH.</P>
Design of a High-Voltage Piezoelectric Converter for Airbag Ignition Modules
Xiao, Hongbing,Du, Yu,Bai, Chunyu,Guo, Zerong,Yen, Kang K. The Korean Institute of Power Electronics 2014 JOURNAL OF POWER ELECTRONICS Vol.14 No.1
Due to the requirements for high reliability and accuracy, safety issues for airbag ignition systems need to be studied. In this paper, a high-voltage piezoelectric converter is designed to improve these requirements in airbag ignition systems. The proposed converter includes an inverter drive circuit, a Rosen piezoelectric transformer (PZT), an output circuit and a feedback control circuit. The key components of the high-voltage piezoelectric transformer are analyzed in detail. In addition, the proposed converter system is simulated and implemented for testing. The experimental results show that when the power supply is turned on, the charging time is less than 800ms. Furthermore, the output voltage of this converter can be kept between 2.9kV and 3.1kV, under high-efficiency constant current charging mode and zero-voltage switching conditions.
Design of a High-Voltage Piezoelectric Converter for Airbag Ignition Modules
Hongbing Xiao,Yu Du,Chunyu Bai,Zerong Guo,Kang K. Yen 전력전자학회 2014 JOURNAL OF POWER ELECTRONICS Vol.14 No.1
Due to the requirements for high reliability and accuracy, safety issues for airbag ignition systems need to be studied. In this paper, a high-voltage piezoelectric converter is designed to improve these requirements in airbag ignition systems. The proposed converter includes an inverter drive circuit, a Rosen piezoelectric transformer (PZT), an output circuit and a feedback control circuit. The key components of the high-voltage piezoelectric transformer are analyzed in detail. In addition, the proposed converter system is simulated and implemented for testing. The experimental results show that when the power supply is turned on, the charging time is less than 800ms. Furthermore, the output voltage of this converter can be kept between 2.9kV and 3.1kV, under high-efficiency constant current charging mode and zero-voltage switching conditions.
Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia
Jung, Hye Seung,Chung, Kun Wook,Won Kim, Jeong,Kim, Jin,Komatsu, Masaaki,Tanaka, Keiji,Nguyen, Yen Hoang,Kang, Tong Mook,Yoon, Kun-Ho,Kim, Ji-Won,Jeong, Yeon Taek,Han, Myoung Sook,Lee, Moon-Kyu,Kim, K Elsevier 2008 Cell metabolism Vol.8 No.4
<P><B>Summary</B></P><P>Autophagy is a cellular degradation-recycling system for aggregated proteins and damaged organelles. Although dysregulated autophagy is implicated in various diseases including neurodegeneration, its role in pancreatic β cells and glucose homeostasis has not been described. We produced mice with β cell-specific deletion of <I>Atg7</I> (<I>autophagy-related 7</I>). <I>Atg7</I> mutant mice showed impaired glucose tolerance and decreased serum insulin level. β cell mass and pancreatic insulin content were reduced because of increased apoptosis and decreased proliferation of β cells. Physiological studies showed reduced basal and glucose-stimulated insulin secretion and impaired glucose-induced cytosolic Ca<SUP>2+</SUP> transients in autophagy-deficient β cells. Morphologic analysis revealed accumulation of ubiquitinated protein aggregates colocalized with p62, which was accompanied by mitochondrial swelling, endoplasmic reticulum distension, and vacuolar changes in β cells. These results suggest that autophagy is necessary to maintain structure, mass and function of pancreatic β cells, and its impairment causes insulin deficiency and hyperglycemia because of abnormal turnover and function of cellular organelles.</P>