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        Recent trends in therapeutic strategies for repairing endometrial tissue in intrauterine adhesion

        Junyan Ma,Hong Zhan,Wen Li,Liqi Zhang,Feng Yun,Ruijin Wu,Jun Lin,Yangyang Li 한국생체재료학회 2021 생체재료학회지 Vol.25 No.4

        Intrauterine adhesion (IUA) is a common gynaecological disease that develops from infection or trauma. IUA disease may seriously affect the physical and mental health of women of childbearing age, which may lead to symptoms such as hypomenorrhea or infertility. Presently, hysteroscopic transcervical resection of adhesion (TCRA) is the principal therapy for IUAs, although its function in preventing the recurrence of adhesion and preserving fertility is limited. Pharmaceuticals such as hormones and vasoactive agents and the placement of nondegradable stents are the most common postoperative adjuvant therapy methods. However, the repair of injured endometrium is relatively restricted due to the different anatomical structures of the endometrium. Recently, the treatment outcome of IUAs has improved with the advancement of hysteroscopic techniques. In particular, the application of bioactive scaffolds combined with tissue engineering technology has proven to have high therapeutic potential or endometrial repair in IUA treatment. Herein, this review has summarized past therapeutic strategies, including postoperative adjuvant therapy, cell or therapeutic molecular delivery therapy methods and bioactive scaffoldbased tissue engineering methods. Therefore, this review presented the recent therapeutic strategies for repairing endometrium treatment and pointed out the issues of clinical concern to provide alternative methods for the management of IUAs.

      • A New Information Sharing Mechanism Based On Distributed Information Storage Model

        Xiaoxuan Ma,Yiping Huang,Junyan Yi 보안공학연구지원센터 2015 International Journal of Database Theory and Appli Vol.8 No.5

        In WWW, due to the distribution of information resources, how to manage and maintain distributed information resources in different nodes is one of the most important problems in the current research. On the basis of analyzing the scalability, efficiency and effectiveness of data exchange, the paper designed a distributed storage model, discussed the organization of the registry information, put forward a dynamically register and update mechanism, designed a distributed information search algorithm. Experimental results show that the biased flooding search algorithm based on index can not only reduce the message load but also can improve the search hit rate.

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        The Effect of H2O2/Fe2+ Catalytic Oxidation System on the Morphology, Structure and Properties of Flake-Like Poly(2,3-dimethylaniline)

        Jun Yan,Li Ma,Mengyu Gan,Xiao Li,Zhitao Li,Jihai Tang,Ying Tu,Haifeng Hu 한국고분자학회 2014 Macromolecular Research Vol.22 No.8

        In this work, flake-like poly(2,3-dimethylaniline) (P(2,3-DMA)) with enhanced thermal stability andanticorrosive ability was synthesized by in situ polymerization using H2O2/Fe2+ catalytic oxidation system, comparingwith traditional oxidant ammonium persulfate (APS) synthetic method. The structure and morphology of thesamples were characterized Fourier transform infrared (FTIR) spectra, X-ray diffraction (XRD) and field-emissionscanning electron microscope (FESEM). The experimental results demonstrated that using H2O2/Fe2+ catalytic oxidationsystem was more inclined to form the two-dimensional P(2,3-DMA) flakes. The enhancement in thermostabilityand corrosion resistance was attributed to the formation of phenazine-like structures in the polymer chains,which could serve as templates to form the flake-like morphology. In addition, using H2O2/Fe2+ catalytic oxidationsystem is more environmental friendly than the APS method that can avoid ammonium pollution on aquatic life aswell as waters.

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