http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Gaoli Zhao,Junping Song,Wei Chen 보안공학연구지원센터 2015 International Journal of Security and Its Applicat Vol.9 No.11
With the rapid and bursting development of computer science and related technology, the design and optimization of network topology has been a most important issue for thee researchers to solve. However, the increasing needs of the current control schemes have already been shown. In this paper, we theoretically analysis the features of neural network structure and convex optimization related method. There are a lot of shortcomings but the cable network should be restricted the wiring in some situations, for example, wiring, reroute workload big, easy to damage, in the network, each node cannot move and so on. With the mathematical optimization, game theory, mathematical economics and optimal control theory to the development of disciplines, convex analysis are increasingly brought to the attention of the people. Our proposed methodology combines the neural network and optimization theory to obtain better performance, the experimental result shows the performance of our approach compared with other state-of-the-art algorithms.
Wan Zheng,Tianfa Li,Junping Wei,Yani Yan,Shanshan Yang 대한약리학회 2023 The Korean Journal of Physiology & Pharmacology Vol.27 No.3
This study is to determine the regulation of nitric oxide synthase 3 (NOS3) by edaravone in mice with hypoxic pulmonary hypertension (HPH). C57BL/6J mice were reared in a hypoxic chamber. HPH mice were treated with edaravone or edaravone + L-NMMA (a NOS inhibitor). Lung tissue was collected for histological assessment, apoptosis analysis, and detection of malondialdehyde, superoxide dismutase, tumor necrosis factor (TNF)-α, interleukin (IL)-6, and NOS3. The levels of serum TNF-α and IL-6 were also measured. Immunohistochemistry was used to visualize the expression of α-smooth muscle actin (SMA) in pulmonary arterioles. Edaravone treatment improved hemodynamics, inhibited right ventricular hypertrophy, increased NOS3 expression, and reduced pathological changes, pulmonary artery wall thickness, apoptotic pulmonary cells, oxidative stress, and the expression of TNF-α, IL-6, and α-SMA in HPH mice. L-NMMA treatment counteracted the lung protective effects of edaravone. In conclusion, edaravone might reduce lung damage in HPH mice by increasing the expression of NOS3.