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Jim Hlavac,Shani Tobias,Lola Sundin,Simon Knowles,Alex Avella Archila 이화여자대학교 통역번역연구소 2023 T&I review Vol.13 No.1
Professional development has become standard practice for many occupational groups. While for some it may be a matter of individual choice, there are often a number of factors and entities that have a stake in the provision of or need for professional development, e.g. professional associations, industry regulatory bodies, training providers, consumer groups, employer representative groups and even governmental authorities. This paper employs the term ‘player’ as a generic term to encompass these different interest groups. This paper then examines the place that professional development has amongst organisations that certify, credential or register interpreters and/or translators to practise professionally. Based on a sample of 12 organisations, we find that five of them have professional development as a requirement for continuing practice, for four organisations it is voluntary and for three there is insufficient information. Comparison shows that the player role of professional association is supportive of professional development, but the most decisive factors were non-involvement as a provider and specific country. Further, we focus on Australia where the major player recently introduced mandatory professional development. Here, we report high rates of uptake not only amongst those who are certified, but also amongst those who are not. (Monash University, Australia; Swinburne University, Australia)
Validating lactate dehydrogenase (LDH) as a component of the PLASMIC predictive tool (PLASMIC-LDH)
Christopher Chin Keong Liam,Jim Yu-Hsiang Tiao,Yee Yee Yap,Yi Lin Lee,Jameela Sathar,Simon McRae,Amanda Davis,Jennifer Curnow,Robert Bird,Philip Choi,Pantep Angchaisuksiri,Sim Leng Tien,Joyce Ching Me 대한혈액학회 2023 Blood Research Vol.58 No.1
Background The PLASMIC score is a convenient tool for predicting ADAMTS13 activity of <10%. Lactate dehydrogenase (LDH) is widely used as a marker of haemolysis in thrombotic thrombocytopenic purpura (TTP) monitoring, and could be used as a replacement marker for lysis. We aimed to validate the PLASMIC score in a multi-centre Asia Pacific region, and to explore whether LDH could be used as a replacement marker for lysis. Methods Records of patients with thrombotic microangiopathy (TMA) were reviewed. Patients’ ADAMTS13 activity levels were obtained, along with clinical/laboratory findings relevant to the PLASMIC score. Both PLASMIC scores and PLASMIC-LDH scores, in which LDH replaced traditional lysis markers, were calculated. We generated a receiver operator characteristics (ROC) curve and compared the area under the curve values (AUC) to determine the predictive ability of each score. Results 46 patients fulfilled the inclusion criteria, of which 34 had ADAMTS13 activity levels of <10%. When the patients were divided into intermediate-to-high risk (scores 5‒7) and low risk (scores 0‒4), the PLASMIC score showed a sensitivity of 97.1% and specificity of 58.3%, with a positive predictive value (PPV) of 86.8% and negative predictive value (NPV) of 87.5%. The PLASMIC-LDH score had a sensitivity of 97.1% and specificity of 33.3%, with a PPV of 80.5% and NPV of 80.0%. Conclusion Our study validated the utility of the PLASMIC score, and demonstrated PLASMIC-LDH as a reasonable alternative in the absence of traditional lysis markers, to help identify high-risk patients for treatment via plasma exchange.