Experimental Study and Numerical Analysis on Mechanical Behavior of T-shape Stiffened Orthotropic Steel-concrete Composite Bridge Decks

Xu Jiang,Qing-Tian Su,Xu Han,Changyu Shao,Liang Chen 한국강구조학회 2017 International Journal of Steel Structures Vol.17 No.3

A new-type of orthotropic steel-concrete composite bridge deck system was developed, by casting the concrete overlay on the top of the orthotropic steel deck ribbed with T-shape steel members. To study its mechanical behavior (in terms of failure mode, load-deflection relationship, concrete crack initiation and propagation, strength, stiffness and so on), two new-type orthotropic steel-concrete composite bridge decks with different section dimensions were experimentally investigated and two reference decks (reinforced concrete deck and orthotropic steel deck) were also involved in the research for comparison. For the two new-type orthotropic steel-concrete composite decks, the average value of ultimate loads per width is 885.7kN, which is 2.35 and 1.61 times of that of the concrete and steel reference decks with almost the same section height. Experimental results proved that the composite deck can effectively control the crack initiation and propagation in the concrete and postpone the yielding of the steel bars and steel plates, due to the composite action between the concrete overlay and the underlying steel plate. Furthermore, the Finite Element (FE) model of the orthotropic steel-concrete composite deck was developed and validated by test results. A parametric study is conducted regarding to the stiffness of shear studs. With the validated FE model, stress distribution in the underlying steel plate and T-shape stiffeners and development of concrete cracking in the concrete overlay were characterized at different load levels.

Protocols for Privacy-Preserving DBSCAN Clustering

XU Wei-jiang,HUANG Liu-sheng,LUO Yong-long,YAO Yi-fei,JING Wei-wei 보안공학연구지원센터 2007 International Journal of Security and Its Applicat Vol.1 No.1

Cooperative computation is one of the most important fields in computer science. In recent years, the development of networking increases the desirability of cooperative computation. But privacy concerns often prevent different parties from sharing their data. Secure multiparty computation techniques can dispel parties’ doubts about revealing privacy information in this situation. On the other hand, Data mining has been a popular research area for more than a decade. However, in many applications, the data are originally collected at different sites owned by different users. This paper considers the problem of privacy preserving DBSCAN clustering over vertically partitioned data based on some results of SMC. An efficient secure intersection protocol is first proposed. The security and complexity of the protocols are also analyzed. The results show that the protocols preserve the privacy of the data and the time complexity as well as the communication complexity is acceptable.

Stochastic Revenue and Cost Model for Determining a BOT Concession Period under Multiple Project Constraints

Xu, Jiang-wei,Moon, Sungwoo American Society of Civil Engineers 2014 Journal of management in engineering Vol.30 No.3

The concession period is an important issue in the contractual arrangement of build-operate-transfer (BOT) projects, such as highways, bridges, and tunnels. In determining the concession period, it is predominantly the toll revenue and construction costs that affect how long the concessionaire needs to be in operation after the completion of the project. This paper presents a stochastic revenue and cost model to determine a concession period under multiple constraints in planning a BOT infrastructure project. In the study, the stochastic process is converted into an equivalent discrete form, and its parameters are estimated using historical data. Based on the process, a principle-agent problem is addressed as a solution to the conflict between the owner and the concessionaire. This methodology incorporates these stakeholders' interests in terms of (1)incentive constraints, and (2)participation constraints. In a case study, a numerical simulation is carried out to assess the risk of toll revenue and construction costs when applied in practice and to demonstrate the applicability of the stochastic revenue and cost model.

Determination of the Optimal Concession Period for BOT Contract Projects Based on a Discrete Stochastic Process Model

Xu, Jiang-Wei,Jiang, Li,Moon, Sungwoo American Society of Civil Engineers 2017 Journal of construction engineering and management Vol.143 No.4

<P>The concession period is one of the most important issues in the contractual arrangement of build-operate-transfer (BOT) projects. When planning a BOT project, the government should aim for a trade-off between the concerned government's satisfaction and the private concessionaire's profit. The objective of this paper is to present a discrete stochastic process model to obtain an optimal concession period considering the trade-off. The process model is developed for a highway project by analyzing the actual traffic data. The net present value (NPV) is calculated for use as a constraint condition that indicates the boundary of risk preference in a utility function. Using a utility function, this paper estimates the duration of concession periods at which the government can both attract investments from private concessionaires and satisfy public opinion. A numerical simulation is applied to demonstrate the applicability of the methodology presented. The result of the simulation shows that the discrete stochastic process model contributes to a better understanding of trade-offs in determining the optimal concession period.</P>

A Novel Preserving Client Privacy and Designate Verifier Auditing Scheme for Cloud Storage

Jiang Xu,Wenliang Chen,Sai Ji,Yongjun Ren,Jin Wang 보안공학연구지원센터 2015 International Journal of Security and Its Applicat Vol.9 No.1

Cloud storage is now an important development trend in information technology. To ensure the integrity of data storage in cloud storing, researchers have present some proof of storage schemes. In some cases, the ability to check data possession is delegated by data owners. Hence, the delegable provable data possession and proxy provable data possession are proposed. However the schemes are not secure since the proxy or designated verifier stores some delegation information in cloud storage servers. In this paper, we propose PC-DV POS scheme, which can preserve clients’ privacy and designate a verifier by the client signed the data blocks. In particular, we utilize group signatures and key exchange to construct homomorphic authenticators, so that only the designated verifier is able to check the integrity of shared data for users without retrieving the entire data, and cannot reveal the identities of signers on all blocks in shared data.

Fine Mapping of Pa-6 Gene for Purple Apiculus in Rice

Xu Liu,Xu Sun,Wenying Wang,Hanfeng Ding,Wei Liu,Guangxian Li,Mingsong Jiang,Changxiang Zhu,Fangyin Yao 한국식물학회 2012 Journal of Plant Biology Vol.55 No.3

Purple apiculus is one of the important agronomic traits of rice. Single-segment substitution line (SSSL) W23-07-6-02-14 in the genetic background of an elite rice variety Huajingxian74 (HJX74) with the substituted interval of RM225-RM217-RM253 on the chromosome 6 was found to have purple apiculus (Pa). To map the gene governing Pa,W23-07-6-02-14 was crossed with the recipient HJX74 to develop an F2 secondary segregation population. The ratio of purple apiculus to green apiculus showed a good fit to 3:1 ratio,indicating that Pa was controlled by a major dominant gene. The gene locus for Pa was tentatively designated as Pa-6. Using 430 individuals from the F2 segregation population, the Pa-6 locus was mapped between two SSR markers RM19556and RM19561 with genetic distances of 0.2 and 0.3 cM,respectively. For fine mapping of the Pa-6 gene, a large F2:3segregation population of 3890 individuals was developed from F2 heterzygous plants in the RM19556-RM19561 region. Recombinant analyses further mapped the Pa-6 gene locus to an interval of 41.7-kb bounded L02 and RM19561. Sequence analysis of this 41.7-kb region revealed that it contains eleven open reading frames (ORFs), of which, ORF5 is classified as the one that is associated with the C (chromogen for anthocyanin) gene, it was presumed to be the candidate gene for Pa. This result provided a foundation of map-based cloning and function analysis of the Pa-6 gene.

Numerical Simulation of Spray Flow in Injector For the Steamjet Engine

( Xu Sheng Shang ),( Jiang Hong Li ),( Ren Hou Zhao ),( Xu Ze Shang ),( Jie Hong Li ) 한국액체미립화학회 2005 한국액체미립화학회 학술강연회 논문집 Vol.2005 No.-

In this paper, according to the work mechanism of SteamJet, With the certain small scaled turbojet for an influence, along flying trajectory calculating mass of import air and injection water, establishing the spray physics model/ mathematics model. Based on the equation of three-dimension Renault average N-S, air to adopt the limited physical volume method, the liquid adopts to the Lagrangian orbit model, with straight injecting the current method ,Simulate the field of air/ liquid two phase flow field to distribute of inlet to carry on mutually. The results indicate that spray have an effect on flow field configuration. It is concluded that the numerical model and CFD method for modeling spray flow processes in gas/liquid injector will be satisfactory. Similar to the SteamJet the United States puts forward, adopting water injection can satisfy to import the conditional request for pressure and temperature of compressor.

Luciferase Assay to Screen Tumour-specific Promoters in Lung Cancer

Xu, Rong,Guo, Long-Jiang,Xin, Jun,Li, Wen-Mao,Gao, Yan,Zheng, You-Xian,Guo, You-Hong,Lin, Yang-Jun,Xie, Yong-Hua,Wu, Ya-Qing,Xu, Rui-An Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11

Objective: Specific promoters could improve efficiency and ensure the safety of gene therapy. The aim of our study was to screen examples for lung cancer. Methods: The firefly luciferase gene was used as a reporter, and promoters based on serum markers of lung cancer were cloned. The activity and specificity of seven promoters, comprising CEACAM5 (carcinoembryonic antigen, CEA), GRP (Gastrin-Releasing Peptide), KRT19 (cytokeratin 19, KRT), SFTPB (surfactant protein B, SP-B), SERPINB3 (Squamous Cell Carcinoma Antigen, SCCA), SELP (Selectin P, Granule Membrane Protein 140kDa, Antigen CD62, GMP) and DKK1 (Dickkopf-1) promoters were compared in lung cancer cells to obtain cancer-specific examples with strong activity. Results: The CEACAM5, DKK1, GRP, SELP, KRT19, SERPINB3 and SFTPB promoters were cloned. Furthermore, we successfully constructed recombinant vector pGL-CEACAM5 (DKK1, GRP, SELP, KRT19, SERPINB3 and SFTPB) contained the target gene. After cells were transfectedwith recombinant plasmids, we found that the order of promoter activity from high to low was SERPINB3, DKK1, SFTPB, KRT19, CEACAM5, SELP and GRP and the order for promoters regarding specificity and high potential were SERPINB3, DKK1, SELP, SFTPB, CEACAM5, KRT19 and GRP. Conclusion: The approach adopted is feasible to screen for new tumour specific promoters with biomarkers. In addition, the screened lung-specific promoters might have potential for use in lung cancer targeted gene therapy research.

Cellular phenotypes as inflammatory mediators in Parkinson’s disease: Interventional targets and role of natural products

Jiang, Xu,Ganesan, Palanivel,Rengarajan, Thamaraiselvan,Choi, Dong-Kug,Arulselvan, Palanisamy Elsevier 2018 BIOMEDICINE AND PHARMACOTHERAPY Vol.106 No.-

<P><B>Abstract</B></P> <P>Pathogenesis of Parkinson’s disease (PD) is undoubtedly a multifactorial phenomenon, with diverse etiological agents. Pro-inflammatory mediators act as a skew that directs disease progression during neurodegenerative diseases. Understanding the dynamics of inflammation and inflammatory mediators in preventing or reducing disease progression has recently gained much attention. Inflammatory neuro-degeneration is regulated via cytokines, chemokines, lipid mediators and immune cell subsets; however, individual cellular phenotypes in the Central Nervous System (CNS) acts in diverse ways whose persistent activation leads to unresolving inflammation often causing unfavorable outcomes in neurodegenerative disease like PD. Specifically, activation of cellular phenotypes like astrocytes, microglia, activation of peripheral immune cells requires different activation signals and agents like (cytokines, misfolded protein aggregates, infectious agents, pesticides like organophosphates, etc.,). However, what is unknown is how the different cellular phenotypes respond uniquely and the role of the factors they secrete alters the signal cascades in the complex neuron-microglial connections in the CNS. Hence, understanding the role of cellular phenotypes and the inflammatory mediators, the cross talk among the signals and their receptors can help us to identify the potential therapeutic target using natural products. In this review we have tried to put together the role of cellular phenotypes as a skew that favors PD progression and we have also discussed how the lack of experimental approaches and challenges that affects understanding the cellular targets that can be used against natural derivatives in alleviating PD pathophysiology. Together, this review will provide the better insights into the role of cellular phenotypes of neuroinflammation, inflammatory mediators and the orchestrating factors of inflammation and how they can be targeted in a more specific way that can be used in the clinical management of PD.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Distinct cellular Phenotypes acts uniquely in the pathogenesis of PD. </LI> <LI> Inflammation can be cause and consequence of PD pathogenesis. </LI> <LI> Flavonoids regulate multiple modulators of inflammation in mitigating PD pathology. </LI> <LI> Diverse intrinsic/extrinsic mediators converge together in glial activation in exacerbating PD pathology. </LI> </UL> </P>

Geochemical character and material source of sediments in the eastern Philippine Sea

Xu, ZhaoKai,Li, AnChun,Jiang, FuQing,Xu, FangJian Elsevier 2008 Chinese science bulletin Vol.53 No.6