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Studies on the Anti-Inflammatory and Analgesic Effects ofExtracts from Marine Sponges
Issa M.I. Fakhr,Nehal A. Hamdy,Mohamed A.A. Radwan,Seham A. El-Batran,Osama A. El Shabrawy 한국생약학회 2006 Natural Product Sciences Vol.12 No.2
specimens of sponges collected from Red Sea, Egypt, were investigated f or their contents ofsecondary metabolites. The crude extracts of the sponges were tested for their anti-inflammatory and analgesiceffects. The toxic effects of the extracts of the two marine sponges were studied. LD50 determination revealed thatthe investigated extracts of ‘Igernella and Ircinia spp’ were 4.69 and 134.7mg/100g b.wt., respectively, whentwo marine sponges extracts showed significant anti-inflamatory and analgesic eff ects. Keywordsanti-inflammatory, analgesic, sponges, Igernella, Ircinia