Fallopian Metaplastic Papillary Tumour: An Atypical Transdifferentiation of the Tubal Epithelium?

Miguel Fdo. Salaza,Isaías Estrada Moscoso,Lorena Troncoso Vázquez,Nubia Leticia López García,Paola Andrea Escalante Abril 대한병리학회 2015 Journal of Pathology and Translational Medicine Vol.49 No.2

A metaplastic papillary tumor of the Fallopian tube is an extremely uncommon condition, with odd and confusing features that make it difficult to categorize as benign or borderline. Here, we summarize all the published cases to date and document the case of a 41-year-old woman diagnosed with this alteration after her last childbirth and ensuing tubal ligation. One of the tubes was bulky and filled with a caramel-like substance encircling a blurry spot. Light microscopy detailed a slender stalk covered by eosinophilic, columnar plump cells, showing atypical nuclei and focal budding. Mitotic figures were absent. The immunohistochemistry panel was positive for pan-cytokeratin, epithelial membrane antigen, cyclin D1, and hormone receptors. Additionally, a proliferation index of less than 5% was rated using Ki-67. The true nature of this tumor (reactive vs neoplastic) is uncertain. Nonetheless, its association with pregnancy suggests an adaptive change, likely similar to the atypical transdifferentiation proposed for Arias-Stella reaction.

Bi2InTaO7 compounds as promising photocatalysts for marine plankton removal

Leticia M. Torres-Martínez,Isaías Juárez-Ramírez,Juan S. Ramos-Garza,Francisco Vázquez-Acosta,Ricardo Gómez,ZhengYi Fu,Soo Wohn Lee 한양대학교 세라믹연구소 2011 Journal of Ceramic Processing Research Vol.12 No.1

The removal of marine plankton, red (Amphidium carterae), and green (Tetraselmis suecica) tide algae, by heterogeneous photocatalysis was carried out using pyrochlore-type semiconductors. The semiconductor, Bi2InTaO7 , was prepared by the solgel method and a solid state reaction. The XRD patterns evidence formation of the pyrochlore phase in the sol-gel materials calcined at low temperatures (600-800 oC). Nanostructured sol-gel materials were observed by SEM. The sol-gel preparation allowed the formation of the pyrochlore-type compound with specific surface areas (7-13 m2g−1) higher than the solid obtained by solid state preparation (< 5 m2g−1). Band gap (Eg) values between 2.1-2.7 eV determined by UV-Vis spectroscopy were obtained. Bi2InTaO7 photocatalysts prepared by the sol-gel method were able to eliminate Tetraselmis suecica and Amphidium carterae algae totally after 50 minutes of UV-irradiation, whereas Bi2InTaO7 by solid state preparation needed more than 1 h.

Synthesis of γ-Al₂O₃ nanopowder by the sol-gel method: Effect of different acid precursors on the superficial, morphological and structural properties

Arquímedes Cruz-López,Odilón Vázquez Cuchillo,Isaías Juárez Ramírez,Lilia M. Bautista-Carrillo,Elvira Zarazua-Morin 한양대학교 세라믹연구소 2008 Journal of Ceramic Processing Research Vol.9 No.5

The main aim of this investigation is to study the effect of three acid precursors (nitric acid, acetic acid and citric acid) during the synthesis of γ-Al2O3 nanopowder by the sol-gel method. The TEM analyses showed that the γ-Al2O3 prepared by using the strongest acid were irregular nanofibers with a length of 50 nm and a diameter of 5 nm, while the γ-Al2O3 prepared with citric acid showed agglomerates. On the other hand, the SEM analyses showed very similar morphologies. The N2-physisorption analyses confirmed that there is a relationship between the acidity and the surface area; and between the presence of mesopores and micropores on the surface of the synthesized Al2O3. The effect of the acid strength on the surface area was as follows: nitric acid (347 m2·g−1) > acetic acid (252 m2·g−1) > citric acid (164 m2·g−1). In addition, the XRD results confirmed that for all the samples thermally treated at 600 oC, the main phase was γ-Al2O3; nevertheless, the thermal analyses showed that the γ-Al2O3 synthesized with the weakest acid was not stable above 600 oC. The main aim of this investigation is to study the effect of three acid precursors (nitric acid, acetic acid and citric acid) during the synthesis of γ-Al2O3 nanopowder by the sol-gel method. The TEM analyses showed that the γ-Al2O3 prepared by using the strongest acid were irregular nanofibers with a length of 50 nm and a diameter of 5 nm, while the γ-Al2O3 prepared with citric acid showed agglomerates. On the other hand, the SEM analyses showed very similar morphologies. The N2-physisorption analyses confirmed that there is a relationship between the acidity and the surface area; and between the presence of mesopores and micropores on the surface of the synthesized Al2O3. The effect of the acid strength on the surface area was as follows: nitric acid (347 m2·g−1) > acetic acid (252 m2·g−1) > citric acid (164 m2·g−1). In addition, the XRD results confirmed that for all the samples thermally treated at 600 oC, the main phase was γ-Al2O3; nevertheless, the thermal analyses showed that the γ-Al2O3 synthesized with the weakest acid was not stable above 600 oC.

Protecting the iTrust Information Retrieval Network against Malicious Attacks

Yung-Ting Chuang,P. Michael Melliar-Smith,Louise E. Moser,Isaí Michel Lombera 한국정보과학회 2012 Journal of Computing Science and Engineering Vol.6 No.3

This paper presents novel statistical algorithms for protecting the iTrust information retrieval network against malicious attacks. In iTrust, metadata describing documents, and requests containing keywords, are randomly distributed to multiple participating nodes. The nodes that receive the requests try to match the keywords in the requests with the metadata they hold. If a node finds a match, the matching node returns the URL of the associated information to the requesting node. The requesting node then uses the URL to retrieve the information from the source node. The novel detection algorithm determines empirically the probabilities of the specific number of matches based on the number of responses that the requesting node receives. It also calculates the analytical probabilities of the specific numbers of matches. It compares the observed and the analytical probabilities to estimate the proportion of subverted or non-operational nodes in the iTrust network using a window-based method and the chi-squared statistic. If the detection algorithm determines that some of the nodes in the iTrust network are subverted or non-operational, then the novel defensive adaptation algorithm increases the number of nodes to which the requests are distributed to maintain the same probability of a match when some of the nodes are subverted or non-operational as compared to when all of the nodes are operational. Experimental results substantiate the effectiveness of the detection and defensive adaptation algorithms for protecting the iTrust information retrieval network against malicious attacks.

Detection of Colletotrichum spp. Resistant to Benomyl by Using Molecular Techniques

Dalha Abdulkadir Isa(Dalha Abdulkadir Isa ),Heung Tae Kim(Heung Tae Kim) 한국식물병리학회 2022 Plant Pathology Journal Vol.38 No.6

Colletotrichum species is known as the major causal pathogen of red pepper anthracnose in Korea and various groups of fungicides are registered for the management of the disease. However, the consistent use of fungicides has resulted in the development of resistance in many red pepper-growing areas of Korea. Effective management of the occurrence of fungicide resistance depends on constant monitoring and early detection. Thus, in this study, various methods such as agar dilution method (ADM), gene sequencing, allele-specific polymerase chain reaction (PCR), and polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) were applied for the detection of benzimidazole resistance among 24 isolates of Colletotrichum acutatum s. lat. and Colletotrichum gloeosporioides s. lat. The result of the ADM showed that C. gloeosporioides s. lat. was classified into sensitive and resistant isolates to benomyl while C. acutatum s. lat. was insensitive at ≥1 μg/ml of benomyl. The sequence analysis of the β-tubulin gene showed the presence of a single nucleotide mutation at the 198th amino acid position of five isolates (16CACY14, 16CAYY19, 15HN5, 15KJ1, and 16CAYY7) of C. gloeosporioides s. lat. Allele-specific PCR and PCR-RFLP were used to detect point mutation at 198th amino acid position and this was done within a day unlike ADM which usually takes more than one week and thus saving time and resources that are essential in the fungicide resistance management in the field. Therefore, the molecular techniques established in this study can warrant early detection of benzimidazole fungicide resistance for the adoption of management strategies that can prevent yield losses among farmers.

Cytochrome b Gene-Based Assay for Monitoring the Resistance of Colletotrichum spp. to Pyraclostrobin

Dalha Abdulkadir Isa(Dalha Abdulkadir Isa ),Heung Tae Kim(Heung Tae Kim) 한국식물병리학회 2022 Plant Pathology Journal Vol.38 No.6

Resistance to pyraclostrobin due to a single nucleotide polymorphism at 143rd amino acid position on the cytochrome b gene has been a major source of concern in red pepper field infected by anthracnose in Korea. Therefore, this study investigated the response of 24 isolates of C. acutatum and C. gloeosporioides isolated from anthracnose infected red pepper fruits using agar dilution method and other molecular techniques such as cytochrome b gene sequencing, polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP), and allele-specific polymerase chain reaction (PCR). The result showed that four isolates were resistant to pyraclostrobin on agar dilution method and possessed GCT (alanine) codon at 143rd amino acid position, whereas the sensitive isolates possessed GGT (glycine). Furthermore, this study illustrated the difference in the cytochrome b gene structure of C. acutatum and C. gloeosporioides. The use of cDNA in this study suggested that the primer Cacytb-P2 can amplify the cytochrome b gene of both C. acutatum and C. gloeosporioides despite the presence of various introns in the cytochrome b gene structure of C. gloeosporioides. The use of allele-specific PCR and PCR-RFLP provided clear difference between the resistant and sensitive isolates. The application of molecular technique in the evaluation of the resistance status of anthracnose pathogen in red pepper provided rapid, reliable, and accurate results that can be helpful in the early adoption of fungicide-resistant management strategies for the strobilurins in the field.

오바스테야마(姨捨山) 풍습과 근대의 고령자 차별

伊佐晴妃(Haruhi Isa),伊佐尙子(Shoko Isa) 한국노년학연구회 2018 한국 노년학연구 Vol.27 No.2

일본은 다른 나라들보다 인구 고령화가 더 빠르게 진행되었고, 고령자 인구비율도 가장 높다. 이로 인한 여러 가지 사회적 문제를 경험하고 있는데, 그 중 하나는 바로 심신의 건강을 상실하여 타인의 케어를 필요로 하는 고령자가 매년 증가하고 있다는 것이다. 유감스럽게도 재택케어이든 시설케어이든 케어의 질 저하로 인해 고령자가 차별이나 학대를 받는 일이 자주 발생하고 있다. 본고에서는 고대 일본에서의 노인을 버렸다는 전설적인 이야기 오바스테야마(姨捨山) 의 현상을 상세히 조망했으며, 이를 토대로 근대의 고령자 존중과 차별 문화를 비교했다. The population aging of Japan is to exceed all other countries, with Japan having the highest proportion of older adults. This have brought Japan to a number of social problems, and one of them is to increase elderly patients who need geriatric care year by year. It is unfortunate that many cases of elder abuse or ageism have been reported in Japan due to the low quality of care for elderly patients who were cared at home or at long-term care facilities. While taking a comprehensive view of the Japanese legendary tale of Obasuteyama phenomena that were told to discard older adults in the ancient society, the modern culture of respecting older adults compared with the phenomena of ageism in this paper.

Three-dimensional stresses analysis in rotating thin laminated composite cylindrical shells

Isa Ahmadi,Mahsa Najafi 국제구조공학회 2016 Steel and Composite Structures, An International J Vol.22 No.5

In this paper, the 3D stress state and inter-laminar stresses in a rotating thin laminated cylinder shell are studied. The thickness of the cylinder is supposed to be thin and it is made of laminated composite material and can have general layer stacking. The governing equations of the cylindrical shell are obtained by employing the Layerwise theory (LWT). The effect of rotation is considered as rotational body force which is induced due to the rotation of the cylinder about its axis. The Layerwise theory (LWT), is used to discrete the partial differential equations of the problem to ordinary ones, in terms of the displacements of the mathematical layers. By applying the Free boundary conditions the solution of the governing equations is completed and the stress state, the inter-laminar stresses, and the edge effect in the rotating cylindrical shells are investigated in the numerical results. To verify the results, LWT solution is compared with the results of the FEM solution and good agreements are achieved. The inter-laminar normal and shear stresses in rotating cylinder are studied and effects of layer stacking and angular velocity is investigated in the numerical results.

Effects of three different diets on the fatty acid profile and sensory properties of fresh Pecorino cheese “Primo Sale”

Isa Fusaro,Melania Giammarco,Michael Odintsov Vaintrub,Matteo Chincarini,Anna Chiara Manetta,Ludovica M. E. Mammi,Alberto Palmonari,Andrea Formigoni,Giorgio Vignola 아세아·태평양축산학회 2020 Animal Bioscience Vol.33 No.12

Objective: This study aimed to evaluate and compare the effects of three different diets on the fatty acids (FA) profile and sensory properties of a characteristic Italian fresh cheese: Pecorino "Primo Sale” (PS). Methods: Fifty-four sheep were divided into three feeding groups: total mixed ration (TMR) enriched with extruded linseed (TL), control diet with TMR without any integration (TC), and pasture (P). During cheese production, six cheeses per experimental group were produced each week, stored for 10 days at 4°C, and then analyzed for chemical composition, FA profile, and sensory properties. Results: Saturated fatty acids (SFA) were significantly higher in PS from group TC (82.11%) than in cheese from other two groups (P 75.48% and TL 66.83%). TL and P groups presented higher values of polyunsaturated fatty acids, 4.35 and 3.65%, respectively, than that of TC group (2.31%). The lowest SFA/unsaturated fatty acid ratio was found in TL and P groups, while the highest was found in the TC group. Vaccenic acid and conjugated linoleic acid (CLA) were higher in group P (p<0.05) than in groups L and TC. Sensory properties of cheese from group P received the highest scores for odor intensity and friability, while control group had a greater chewing consistency. Overall, all cheeses received good scores for acceptability. Conclusion: In conclusion, this study showed how the integration of extruded linseed improved the FA profile of fresh pecorino cheese PS preserving its sensory properties. Levels of CLA in the PS group achieved using this approach was not higher than that in a grazing diet. Cheeses from groups P and L contained a higher value of FA, with nutritional implications for humans, when compared with un-supplemented diet. Linseed may be a good feeding strategy when pasture is not available.

The Effect of Endoscopic Tympanoplasty on Cochlear Function

Isa Kaya,Goksel Turhal,Arin Ozturk,Sercan Gode,Cem Bilgen,Tayfun Kirazli 대한이비인후과학회 2018 Clinical and Experimental Otorhinolaryngology Vol.11 No.1

Objectives. The aim of this prospective clinical study was to measure the audiologic outcomes of the patients that underwent endoscopic transcanal cartilage tympanoplasty, and to investigate the effects on cochlear function. Methods. Thirty-three patients (33 ears) who were diagnosed with noncomplicated chronic otitis media and underwent endoscopic transcanal cartilage tympanoplasty technique were included. Pre- and postoperative first month distortion product otoacoustic emission (DPOAE) signal-to-noise ratio (SNR), bone conduction hearing levels and air bone gap (ABG) values were measured and total endoscope usage time was noted. Results. Preoperative median SNR measurements at 0.5, 1, 2, and 4 kHz were 6 dB (1–11; interquartile range [IQR], 1), 6 dB (4–20; IQR, 1), 7 dB (3–26; IQR, 5) and 5.50 dB (0–9; IQR, 3), respectively. Postoperative median SNR measurements at 0.5, 1, 2, and 4 kHz were 6 dB (3–9; IQR, 1), 6 dB (2–21; IQR, 3), 7 dB (2–20; IQR, 3), and 6 dB (0–10; IQR, 7), respectively. Regarding the DPOAE measurements, there was no statistically significant difference between the SNR values of all given frequencies (P>0.05). Regarding the pure tone audiometry (PTA) measurements, bone conduction was significantly better at 0.5 and 1 kHz, postoperatively (P<0.05) and there was statistically significant difference at 2 and 4 kHz (P>0.05). Additionally, no statistically significant correlation was found between the SNR and PTA measurements and the endoscope usage time (P>0.05). Conclusion. We suggested that cochlear functions and sensorineural hearing remained stable after endoscopic transcanal cartilage tympanoplasty and cold light source doesn’t cause significant adverse effects cochlear functions.