http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Investigation of persistent infection with bovine viral diarrhea in Korean native cattle
Hye-Young Jeoung(Hye-Young Jeoung),Eun-Yong Lee(Eun-Yong Lee),Se-Jin Park(Se-Jin Park),Hyung-Woo Kang(Hyung-Woo Kang),Ji-Young Park(Ji-Young Park),Kyoung-Ki Lee(Kyoung-Ki Lee),Bok-Kyung Ku(Bok-Kyung K 한국예방수의학회 2022 한국예방수의학회 학술대회자료집 Vol.2022 No.-
Molecular characterization and variability of the genes from EHV-1 in Korea
Hye-young Jeoung(Hye-young Jeoung),Hyung-Woo Kang(Hyung-Woo Kang),Eun-Yong Lee(Eun-Yong Lee),Kyoung-Ki Lee(Kyoung-Ki Lee),Ji-Young Park(Ji-Young Park),Bok-Khyung Ku(Bok-Khyung Ku) 한국예방수의학회 2022 한국예방수의학회 학술대회자료집 Vol.2022 No.-
Jeoung, Hye-Young,Lee, Soo-Kyoung,Park, Jee-Yong,Kim, Hyun-Jeong,Yang, Sun-Joo,Lee, Sang Kyu,Ko, Jin A,Yang, Hyoung-Seok,Park, Changnam,Kim, Sung-Hee,Kang, Hae-Eun,Choi, Jun-Gu Elsevier 2018 Journal of equine veterinary science Vol.69 No.-
<P><B>Abstract</B></P> <P>Contagious equine metritis is a highly transmissible venereal disease of horses caused by the bacterium, <I>Taylorella equigenitalis</I>. After the first identification of <I>T. equigenitalis</I> in Korea in 2015, targeted surveillance of Thoroughbreds was conducted using real-time polymerase chain reaction. Initially, the prevalence of <I>T. equigenitalis</I> in the Thoroughbred population tested was 13.5% (71/526). All positive animals were placed under quarantine and treated according to previously described protocols (Jeoung et al., J Equine Vet Sci, 2016; 47:42–6). After the initial outbreak identification, annual national surveillance for <I>T. equigenitalis</I> was conducted from 2015 to 2017, and by 2017, prevalence was reduced to 1.0% (22/2,171). Most positive cases were located in Jeju province, the major horse-rearing region in Korea. A total of 12 <I>T. equigenitalis</I> strains were isolated during the surveillance period, and multilocus sequence typing (MLST) and eBURST analysis were applied to determine epidemiological characteristics. All Korean strains showed a unique MLST allelic profile (1-2-1-2-2-2-1; <I>gltA</I>-<I>gyrB</I>-<I>fh</I>-<I>shmt</I>-<I>tyrB</I>-<I>adk</I> in order) and were classified as sequence type 55. In addition, they showed little relationship with <I>T. equigenitalis</I> strains isolated from other countries. Considering the unique biological and genetic characteristics of the Korean isolates, effective quarantine measures and continued surveillance will be required to eradicate the disease and prevent incursions of additional <I>T. equigenitalis</I> strains into Korea.</P> <P><B>Highlights</B></P> <P> <UL> <LI> In Korea, a national <I>T. equigenitalis</I> surveillance program conducted in Thoroughbred horses showed a decrease in prevalence from 13.5% in 2015 to 1.0% in 2017. </LI> <LI> Characterization of 12 Korean <I>T. equigenitalis</I> isolates showed identical bacteriological properties and demonstrated a unique multilocus sequence typing (MLST) profile (1-2-1-2-2-1). </LI> <LI> All Korean <I>T. equigenitalis</I> isolates were classified as MLST sequence type 55 (ST55) and showed little genetic relationship with isolates from other countries. </LI> </UL> </P>
Jeoung, Hye-Young,Song, Dae-Sub,Jeong, Woo Seog,Lee, Won-Ha,Song, Jae-Young,An, Dong-Jun The Society ; Maruzen Co. [distributor] 2013 The Journal of veterinary medical science Vol.75 No.1
<P>A multiplex reverse transcription polymerase chain reaction (mRT-PCR) assay was developed for the simultaneous detection of canine distemper virus (CDV), canine respiratory coronavirus (CRCoV) and canine influenza virus (CIV). These viral pathogens are all causative agents of canine infectious respiratory disease (CIRD). The sensitivity and specificity of the mRT-PCR were determined by comparing it to a rapid antigen test (RAT) or immuno-chromatography test kit and reverse transcription-polymerase chain reaction (RT-PCR) in the detection of CDV, CRCoV and CIV antigens present in 100 clinical samples (nasal swabs and whole blood samples) from 50 dogs with respiratory disease symptoms. This study revealed that mRT-PCR had almost exactly the same performance or results were almost 100% in agreement with that of RT-PCR and RAT both in terms of the assay sensitivity and specificity which was more highly evident in detecting CIV, CDV and CRCoV antigens present in canine nasal swab samples. Therefore, this assay could be a better alternative for the definitive and simultaneous ante-mortem detection of the three viral pathogens that cause CIRD by using nasal swabs.</P>
Hye-Young Song,In-Jeoung Baek,Seung-Hee Ryu,Je-won Ryu,Eun-Young Park,Seung-Ho Heo 한국실험동물학회 2021 한국실험동물학회 학술발표대회 논문집 Vol.2021 No.7
Human immune system (HIS) mice have become valuable animal models for the study of human diseases, and peripheral blood mononuclear cell engrafted humanized mice (PBMCHu mice) mice provide a useful platform for cancer immunotherapy research. However, there have been limitations such as insufficient engraftment of human immune cells and development of graft versus host disease (GVHD). To overcome these limitation, we generated CD47; Rag2; IL2rg triple KO mice (TKO) using NOD-Rag2null IL2rgnull mice (DKO) and transplantation efficacy of human leukocytes and GVHD incidence were compared in PBMC-Hu mice. Examining flow cytometry results, more than 25% Human CD45+ cells were observed in both TKO groups from 3 weeks after PBMC administration, and it was observed more than 1 week later in DKO groups. Most of the engrafted cells were CD3+ T cells, and some CD19 B cells and CD66b+ granulocytes were also observed. The ratio of human leukocytes engraftment was greater in TKO mice, however, clinical symptoms of GVHD such as weight loss, jaundice, anemia and death of animals were more severe than in DKO mice. In histopathology, inflammatory cell aggregation, necrotic or apoptotic cells were observed in liver, lung and kidney, and semi-quantitative lesion scores were greater in TKO mice groups. Human CD45, CD3 and CD19 positive cells were also observed in immunohistochemistry. CD47 protein present on myeloid cells and inhibit phagocytosis through ligation of signal-regulatory protein alpha (SIRPα). In this study, we generate TKO mice to improve PBMC-Hu mice. Engraftment of human leukocytes was increased, but symptoms of GVHD were also more severe in TKO mice than DKO mice. Further study for overcoming development of GVHD and poor engraftment of leukocytes other than T cells is needed.
Tissue-specific Regulation of Calbindin-D<SUB>9κ</SUB> Gene in Transgenic Mouse
Hye Kyoung Song,Joo-Hyoung Kang,Kun Yeong Lee,Jae-Hoon Choi,Sun Ja Cho,Young-Han Ryu,Eun-Young Kim,Seung Phil Park,Hye Jin Kim,Eun-Kyoung Kim,Yun Jeoung Seo,Sung Kyu Park,Goo Taeg Oh(오구택) 한국실험동물학회 2004 한국실험동물학회 학술발표대회 논문집 Vol.2004 No.-
Seroprevalence of subtype H3 influenza A virus in South Korean cats
Jeoung, Hye-Young,Shin, Bo-Hye,Lee, Won-Ha,Song, Dae-Sub,Choi, Young-Ki,Jeong, WooSeog,Song, Jae-Young,An, Dong-Jun SAGE Publications 2012 JOURNAL OF FELINE MEDICINE AND SURGERY Vol.14 No.10
<P>To investigate the potential transmission of subtype H3 influenza virus to cats, a serological survey was carried out in South Korea. Serum samples (n=1027) were obtained from 809 pet cats and 218 domesticated cats living in urban colonies (D-cats) from 2008 to 2010, and tested using an influenza anti-nucleoprotein (NP)-specific enzyme-linked immunosorbent assay (ELISA) and the haemagglutination inhibition (HI) test, which was recommended by the World Organization for Animal Health. Anti-influenza virus antibodies were detected in 3.12% and 2.43% of cat sera tested using the NP-specific ELISA and HI test, respectively. Anti-H3 antibodies were also identified when the HI assay was used for influenza virus serotyping. These data may indicate the sporadic transmission of subtype H3 influenza virus from other infected species to cats in South Korea.</P>