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RISS 인기검색어
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- 저자 : Huimin Zhi (검색결과 3 건)
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Zhi Chen,Shuangfeng Chu,Xin Xu,Jingyi Jiang,Wenqiang Wang,Hongliang Shen,Mingxun Li,Huimin Zhang,Yongjiang Mao,Zhangping Yang 한국유전학회 2019 Genes & Genomics Vol.41 No.10
Background As cattle represent one of the most important livestock species for meat production, control of muscle development in regards to quality is an important research focus. Objectives In this study, the phenotypic quality traits and its associations with DNA methylation levels of the longissimus muscle in two cattle breeds were studied. Methods The pH value, water loss rate, fat and protein and fatty acid content were measured in three beef cattle breeds of longissimus mucle; The longissimus mucle was analyzed by MethylRAD-seq and RNA-seq. The differentially methylated and differentially expressed related genes were subjected to BSP. Results Methylation status of longissimus mucle was analyzed by MethylRAD-seq. Compared with Simmental, there were 39 differentially methylated and expressed genes in muscle of Yunling cattle, and 123 differentially methylated and expressed genes in Wenshan muscle. A combined analysis of MethylRAD-seq and RNA-seq results revealed differential methylation and expression level of 18 genes between Simmental and Wenshan cattle, and 14 genes between Simmental and Yunling cattle. In addition, 28 genes were differentially methylated between Wenshan and Yunling cattle. Results of promoter methylation analysis of ACAD11, FADS6 and FASN showed that the overall degree of DNA methylation of FADS6 and FASN was negatively correlated with their expression levels. Methylation level of FASN in Simmental was greater than Yunling and Wenshan. The degree of methylation at the FADS6 CpG4 site was significantly higher in Simmental than that in Yunling. The levels of methylation at the CpG7 locus of the Simmental and Yunling breeds were greater than Wenshan cattle. A negative correlation was detected between the methylation levels and the expression of FASN CpG1, CpG2, CpG3, CpG5, CpG7, and CpG10. Conclusion The functional and molecular regulatory mechanism of the genes related to meat quality can be revealed systematically from aspects of the genetic and epigenetic regulation. These studies will help to further explore the molecular mechanisms and phenotypic differences that regulate growth and quality of different breeds of cattle.
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Jumei Wei,Huimin Zhi,Xiaowu Mu 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.12
In this paper, the problem of the E-exponential stability of linear switched singular systems composed of stable and unstable subsystems in discrete-time case is investigated. By using a multiple discontinuous Lyapunov function approach and exploring the properties of mode-dependent average dwell time(MDADT) switching signal, new sufficient conditions of E-exponential stability for linear switched singular systems are presented. Compared with the existing results, the proposed method is more flexible and tighter bounds on MDADT can be obtained. Finally, a numerical example is provided to illustrate the effectiveness of the proposed criteria.
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Yang, Jie,Uddin, Mohammad Afsar,Tang, Yumin,Wang, Yulun,Wang, Yang,Su, Huimin,Gao, Rutian,Chen, Zhi-Kuan,Dai, Junfeng,Woo, Han Young,Guo, Xugang American Chemical Society 2018 ACS APPLIED MATERIALS & INTERFACES Vol.10 No.27
<P>We present here a series of wide-band-gap (<I>E</I><SUB>g</SUB>: >1.8 eV) polymer donors by incorporating thiophene-flanked phenylene as an electron-donating unit and quinoxaline as an electron-accepting co-unit to attain large open-circuit voltages (<I>V</I><SUB>oc</SUB>s) and short-circuit currents (<I>J</I><SUB>sc</SUB>s) in nonfullerene organic solar cells (OSCs). Fluorination was utilized to fine-tailor the energetics of polymer frontier molecular orbitals (FMOs) by replacing a variable number of H atoms on the phenylene moiety with F. It was found that fluorination can effectively modulate the polymer backbone planarity through intramolecular noncovalent S···F and/or H···F interactions. Polymers (P2-P4) show an improved molecular packing with a favorable face-on orientation compared to their nonfluorinated analogue (P1), which is critical to charge carrier transport and collection. When mixed with IDIC, a nonfullerene acceptor, P3 with two F atoms, achieves a remarkable <I>V</I><SUB>oc</SUB> of 1.00 V and a large <I>J</I><SUB>sc</SUB> of 15.99 mA/cm<SUP>2</SUP>, simultaneously, yielding a power-conversion efficiency (PCE) of 9.7%. Notably, the 1.00 V <I>V</I><SUB>oc</SUB> is among the largest values in the IDIC-based OSCs, leading to a small energy loss (<I>E</I><SUB>loss</SUB>: 0.62 eV) while maintaining a large PCE. The P3:IDIC blend shows an efficient exciton dissociation through hole transfer even under a small energy offset of 0.16 eV. Further fluorination leads to the polymer P4 with increased chain-twisting and mismatched FMO levels with IDIC, showing the lowest PCE of 2.93%. The results demonstrate that quinoxaline-based copolymers are promising donors for efficient OSCs and the fluorination needs to be fine-adjusted to optimize the interchain packing and physicochemical properties of polymers. Additionally, the structure-property correlations from this work provide useful insights for developing wide-band-gap polymers with low-lying highest occupied molecular orbitals to minimize <I>E</I><SUB>loss</SUB> and maximize <I>V</I><SUB>oc</SUB> in nonfullerene OSCs for efficient power conversion.</P> [FIG OMISSION]</BR>
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