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Cell panel electrical test for evaluating the electrical characteristics of liquid crystal displays
Yasuhiro Miyake,Atsuto Ota,Hidekazu Nishimura 한국정보디스플레이학회 2015 Journal of information display Vol.16 No.1
Electrical models of liquid crystal display (LCD) have been studied and used in design simulation. Using the right LCD models is indispensable to accomplish high-quality and highly reliable LCDs. This paper presents a cell panel electrical test (Cell-E Test) for evaluating the electrical characteristics of LCDs. The Cell-E Test was derived from in-process electrical testing for thin film transistor arrays, and utilizes charge measurement for measuring the capacitance value of a pixel. The capacitance-voltage (C-V) and capacitance-time (C-t) characteristics can be measured using a sweeping-applied voltage and based on the period of applying voltage in the Cell-E Test. In this study, actual C-V and C-t characteristics were measured by applying the Cell-E Test to a twisted-nematic active-matrix LCD (TN AM-LCD). The parameters of liquid crystal models were extracted from the data measured using the least-squares method, to show that design models can be verified with the actual parameters of cell panels through the Cell-E Test.
<sup>123</sup>I-Labeled oxLDL Is Widely Distributed Throughout the Whole Body in Mice
Nakano, Atushi,Kawashima, Hidekazu,Miyake, Yoshinori,Zeniya, Tsutomu,Yamamoto, Akihide,Koshino, Kazuhiro,Temma, Takashi,Fukuda, Tetsuya,Fujita, Yoshiko,Kakino, Akemi,Kanaya, Shigehiko,Sawamura, Tatsuy 대한핵의학회 2018 핵의학 분자영상 Vol.52 No.2
Purpose Oxidized low-density lipoprotein (oxLDL) plays a key role in endothelial dysfunction, vascular inflammation, and atherogenesis. The aim of this study was to assess blood clearance and in vivo kinetics of radiolabeled oxLDL in mice. Methods We synthesized $^{123}I-oxLDL$ by the iodine monochloride method, and performed an uptake study in CHO cells transfected with lectin-like oxLDL receptor-1 (LOX-1). In addition, we evaluated the consistency between the $^{123}I-oxLDL$ autoradiogram and the fluorescence image of DiI-oxLDL after intravenous injection for both spleen and liver. Whole-body dynamic planar images were acquired 10 min post injection of $^{123}I-oxLDL$ to generate regional time-activity curves (TACs) of the liver, heart, lungs, kidney, head, and abdomen. Regional radioactivity for those excised tissues as well as the bladder, stomach, gut, and thyroid were assessed using a gamma counter, yielding percent injected dose (%ID) and dose uptake ratio (DUR). The presence of $^{123}I-oxLDL$ in serum was assessed by radio-HPLC. Results The cellular uptakes of $^{123}I-oxLDL$ were identical to those of DiI-oxLDL, and autoradiograms and fluorescence images also exhibited consistent distributions. TACs after injection of $^{123}I-oxLDL$ demonstrated extremely fast kinetics. The radioactivity uptake at 10 min post-injection was highest in the liver ($40.8{\pm}2.4%$ ID). Notably, radioactivity uptake was equivalent throughout the rest of the body ($39.4{\pm}2.7%$ ID). HPLC analysis revealed no remaining $^{123}I-oxLDL$ or its metabolites in the blood. Conclusion $^{123}I-oxLDL$ was widely distributed not only in the liver, but also throughout the whole body, providing insight into the pathophysiological effects of oxLDL.