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Henrique Gonçalves Teixeira 한국 포르투갈-브라질 학회 2013 포르투갈-브라질 연구 Vol.10 No.2
본 연구는 2012년 동티모르 총선 과정에서 보여진 동티모르 여성의 참여를 정치적, 행정적 그리고 유권자의 관점에서 살펴보고 있다. 기존 동티모르에 대한 연구들은 주로 지역 수준에서의 여성할당제, 시민사회의 젊은 여성, 그리고 양성평등 촉진을 목적으로한 공여자들의 역할에 대해 다루었다. 그러나 2006년 여성할당제 실시에도 불구하고, 2012년 선거과정은 선거에 대한 인식과 참여라는 점에서 남녀의 차이를 분명히 보여주는 계기가 되었다. 대부분의 관점에서 볼 때, 여전히 동티모르 남성들은 선거의 유일한 행위자이며 양성평등 촉진을 위해서는 새로운 접근이 시도될 필요가 있다. This paper examines the participation of Timorese women in the electoral process during the 2012 national elections, from the political, administrative and voters’ point of view. Existing literature on Timor-Leste has explored the issue of gender quotas at the local level, young women in civil society, and the role of aid donors at promoting gender equality in the country. However, the 2012 electoral process was a good opportunity to observe the gap between men and women in terms of electoral participation and consciousness in spite of the advances obtained through the gender quotas implemented in 2006. Findings confirm that Timorese men are still the sole conductors of the elections from most perspectives, and a new approach is necessary in order for the country to advance further in gender equality.
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Considerações sobre o Ensino de Pronúncia do Português para Falantes de Coreano
Henrique Gonçalves Teixeira 한국 포르투갈-브라질 학회 2014 포르투갈-브라질 연구 Vol.11 No.2
This paper first proposes a brief comparison between the phonological systems of Korean and Brazilian Portuguese, using the Model of Contrastive Analysis. Such comparison is then used at predicting and testing pronunciation mistakes made by Korean speakers who learn Brazilian Portuguese, in order to verify which aspects need more attention by both teacher and student. Finally, it presents an analysis of six Portuguese language books for Korean learners and checks how they approach and/or explain pronunciation to the readers. The findings reveal that teaching pronunciation in Korea is still a field little explored and yet to be developed, especially in specific contexts such as teaching Brazilian Portuguese pronunciation for Korean speakers.
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EGFL7 expression profile in IDH-wildtype glioblastomas is associated with poor patient outcome
Bruno Henrique Bressan da Costa,Aline Paixão Becker,Luciano Neder,Paola Gyuliane Gonçalves,Cristiane de Oliveira,Allan Dias Polverini,Clara Carlos Afonso,Gustavo Ramos Teixeira,Rui Manuel Reis,Lucas T 대한병리학회 2022 Journal of Pathology and Translational Medicine Vol.56 No.4
Background: Despite the advances in glioblastoma (GBM) treatment, the average life span of patients is 14 months. Therefore, it is urgent to identity biomarkers of prognosis, treatment response, or development of novel treatment strategies. We previously described the association of high epidermal growth factor-like domain multiple 7 (EGFL7) expression and unfavorable outcome of pilocytic astrocytoma patients. The present study aims to analyze the prognostic potential of EGFL7 in GBM isocitrate dehydrogenase (IDH)-wildtype, using immunohistochemistry and in silico approaches.Methods: Spearman’s correlation analysis of The Cancer Genome Atlas RNA sequencing data was performed. The genes strongly correlated to EGFL7 expression were submitted to enrichment gene ontology and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis. Additionally, EGFL7 expression was associated with patient overall survival. The expression of EGFL7 was analyzed through immunohistochemistry in 74 GBM IDH-wildtype patients’ samples, and was associated with clinicopathological data and overall survival.Results: In silico analysis found 78 genes strongly correlated to EGFL7 expression. These genes were enriched in 40 biological processes and eight KEGG pathways, including angiogenesis/vasculogenesis, cell adhesion, and phosphoinositide 3-kinase–Akt, Notch, and Rap1 signaling pathways. The immunostaining showed high EGFL7 expression in 39 cases (52.7%). High immunolabelling was significantly associated with low Karnofsky Performance Status and poor overall survival. Cox analysis showed that GBMs IDH-wildtype with high EGFL7 expression presented a higher risk of death compared to low expression (hazard ratio, 1.645; 95% confidence interval, 1.021 to 2.650; p = .041).Conclusions: This study gives insights regarding the genes that are correlated with EGFL7, as well as biological processes and signaling pathways, which should be further investigated in order to elucidate their role in glioblastoma biology.
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