On the Laplace Transform and the Generalized Weyl Fractional Integral Operator Involving the H-function

S. P. Goyal,R. Mukherjee,R. Jain 경북대학교 자연과학대학 수학과 2004 Kyungpook mathematical journal Vol.44 No.4

In the present paper, we establish a general theorem exhibiting a relationship existing between the Laplace transform and the generalized Weyl fractional integral operator (FIO) of related functions. This theorem is very general in nature and involves a multidimensional series with essentially arbitrary sequence of complex numbers. By suitably assigning different values to these sequences, one can easily evaluate the generalized Weyl fractional integral operator of special functions of several variables. References of known results which follow as special cases of our theorem are also cited. We have obtained here as applications of the theorem, the generalized Weyl fractional integral of(Srivastava-Daoust) generalized Lauricella function which gives a number of results involving special functions of one or more variables merely by specializing the parameters. The results recently obtained by R. Jain and M. A. Pathan and S. P. Goyal and Ritu Goyal,etc. follow as special cases of our main findings.

Investigation into the mechanism of anti-asthmatic action of Lepidium sativum

Goyal, BR,Goyal, RK,Mehta, Anita A Kyung Hee Oriental Medicine Research Center 2008 Oriental pharmacy and experimental medicine Vol.8 No.3

We have studied the possible mechanism of anti-asthmatic action of ethanolic extracts of dried seeds of Lepidium sativum (EXLS, 400 mg/kg) using various experimental models. EXLS produced an increase in the Pre-Convulsion Dyspnoea time induced by histamine and acetylcholine aerosol, a significant reduction in the elevated leucocyte counts in the Broncho-Alveolar Lavage fluid of sensitized guinea-pigs and reduction in the paw edema volume as compared to the control rats. Treatment with EXLS also produced decrease in the elevated histamine release from the sensitized guinea-pig lungs. The anti-asthmatic anti-inflammatory responses of EXLS was supported by improvement in microscopic changes like infiltration of inflammatory cells, submucosal edema, epithelial desquamation and reduced lumen size of the bronchi. The $pD_2$ values of histamine in tracheal chain and taenia-coli were significantly greater and that in lung strip was lower in the sensitized animals as compared to control. Treatment of sensitized guinea pigs with EXLS significantly decreased $pD_2$ values of histamine in all three preparations. Our data suggest the prevention of hyper-responsiveness in bronchial smooth muscles and inhibition of the immediate hypersensitive reaction, histamine release in the lungs and the infiltration of various inflammatory cells as the possible mechanisms of anti-asthmatic activity of EXLS.

Efficacy of interventional treatment strategies for managing patients with cervicogenic headache: a systematic review

Goyal Sonal,Kumar Ajit,Mishra Priyanka,Goyal Divakar 대한마취통증의학회 2022 Korean Journal of Anesthesiology Vol.75 No.1

Cervicogenic headache (CeH) is caused by the disorder of the cervical spine and its anatomical structures. Patients who fail to respond to conservative therapies can undergo interventional treatment. The purpose of this review is to describe the various interventions and compare their relative efficacies. Although a few reviews have been published focusing on individual interventions, reviewing studies on other available treatments and establishing the most efficacious approach is still necessary. We performed a systematic review of studies available on the various interventions for CeH. The PubMed, Embase, and Cochrane databases were searched for literature published between January 2001 and March 2021. Based on the inclusion criteria, 23 articles were included. Two reviewers independently extracted the data from the studies and summarized them in a table. Eleven of twenty-three studies evaluated the effect of radiofrequency ablation (RFA), 5 evaluated occipital nerve blocks, 2 each for facet joint injections and deep cervical plexus blocks, and 1 study each evaluated atlantoaxial (AA) joint injections, cervical epidural injection, and cryoneurolysis. Most of the studies reported pain reduction except 2 studies on RFA. In conclusion, based on the available literature, occipital nerve blocks, cervical facet joint injection, AA joint injection, deep cervical plexus block, cervical epidural injection may be reasonable options in refractory cases of CeH. RFA was found to have favorable long-term outcomes, while better safety has been reported with pulsed therapy. However, our review revealed only limited evidence, and more randomized controlled trials are needed to provide more conclusive evidence.

Pharmacological classification of herbal anti-asthmatics

Goyal, Bhoomika R,Agrawal, Babita B,Goyal, Ramesh K,Mehta, Anita A Kyung Hee Oriental Medicine Research Center 2007 Oriental pharmacy and experimental medicine Vol.7 No.1

Bronchial asthma is a major public health problem worldwide and the morbidity and mortality of asthma have increased in last few decades. There is high prevalence of usage of alternative traditional system of medicines for the treatment of asthma. Large numbers of medicinal plant preparations have been reported to possess anti-asthmatic effects. Plant cells are now considered to be the chemical factories synthesizing a large variety of chemical compounds. Further, Ayurvedic system of medicine has an elaborate description of asthma from the earliest times describing it as 'Shwasa' meaning disease pertaining to breathing. This review classifies the antiasthmatics herbs based on the possible mechanism of action reported. Thus, these plants can be used to obtain a polyherbal formulation which contains various herbs acting at particular sites of the pathophysiological cascade of asthma for prophylaxis as well as for the treatment of asthma.

Radial Basis (Exact Fit) and Linear Layer (Design) ANN Models for Shelf Life Prediction of Processed Cheese

Sumit Goyal,Gyanendera Kumar Goyal 보안공학연구지원센터(IJUNESST) 2012 International Journal of u- and e- Service, Scienc Vol.5 No.1

Investigation into the mechanism of anti–asthmatic action of Lepidium sativum

BR Goyal,RK Goyal,Anita A Mehta 경희대학교 융합한의과학연구소 2008 Oriental Pharmacy and Experimental Medicine Vol.8 No.3

We have studied the possible mechanism of anti-asthmatic action of ethanolic extracts of dried seeds of Lepidium sativum (EXLS, 400 mg/kg) using various experimental models. EXLS produced an increase in the Pre-Convulsion Dyspnoea time induced by histamine and acetylcholine aerosol, a significant reduction in the elevated leucocyte counts in the Broncho- Alveolar Lavage fluid of sensitized guinea-pigs and reduction in the paw edema volume as compared to the control rats. Treatment with EXLS also produced decrease in the elevated histamine release from the sensitized guinea-pig lungs. The anti-asthmatic anti-inflammatory responses of EXLS was supported by improvement in microscopic changes like infiltration of inflammatory cells, submucosal edema, epithelial desquamation and reduced lumen size of the bronchi. The pD2 values of histamine in tracheal chain and taenia-coli were significantly greater and that in lung strip was lower in the sensitized animals as compared to control. Treatment of sensitized guinea pigs with EXLS significantly decreased pD2 values of histamine in all three preparations. Our data suggest the prevention of hyper-responsiveness in bronchial smooth muscles and inhibition of the immediate hypersensitive reaction, histamine release in the lungs and the infiltration of various inflammatory cells as the possible mechanisms of anti-asthmatic activity of EXLS. We have studied the possible mechanism of anti-asthmatic action of ethanolic extracts of dried seeds of Lepidium sativum (EXLS, 400 mg/kg) using various experimental models. EXLS produced an increase in the Pre-Convulsion Dyspnoea time induced by histamine and acetylcholine aerosol, a significant reduction in the elevated leucocyte counts in the Broncho- Alveolar Lavage fluid of sensitized guinea-pigs and reduction in the paw edema volume as compared to the control rats. Treatment with EXLS also produced decrease in the elevated histamine release from the sensitized guinea-pig lungs. The anti-asthmatic anti-inflammatory responses of EXLS was supported by improvement in microscopic changes like infiltration of inflammatory cells, submucosal edema, epithelial desquamation and reduced lumen size of the bronchi. The pD2 values of histamine in tracheal chain and taenia-coli were significantly greater and that in lung strip was lower in the sensitized animals as compared to control. Treatment of sensitized guinea pigs with EXLS significantly decreased pD2 values of histamine in all three preparations. Our data suggest the prevention of hyper-responsiveness in bronchial smooth muscles and inhibition of the immediate hypersensitive reaction, histamine release in the lungs and the infiltration of various inflammatory cells as the possible mechanisms of anti-asthmatic activity of EXLS.

Pharmacological classification of herbal anti-asthmatics

Bhoomika R Goyal,Babita B Agrawal,,Ramesh K Goyal,Anita A Mehta 경희대학교 융합한의과학연구소 2007 Oriental Pharmacy and Experimental Medicine Vol.7 No.1

Bronchial asthma is a major public health problem worldwide and the morbidity and mortality of asthma have increased in last few decades. There is high prevalence of usage of alternative traditional system of medicines for the treatment of asthma. Large numbers of medicinal plant preparations have been reported to possess anti-asthmatic effects. Plant cells are now considered to be the chemical factories synthesizing a large variety of chemical compounds. Further, Ayurvedic system of medicine has an elaborate description of asthma from the earliest times describing it as ‘Shwasa’ meaning disease pertaining to breathing. This review classifies the antiasthmatics herbs based on the possible mechanism of action reported. Thus, these plants can be used to obtain a polyherbal formulation which contains various herbs acting at particular sites of the pathophysiological cascade of asthma for prophylaxis as well as for the treatment of asthma.

Adsorption of p-Nitrophenol by Surface Modified Carbons from Aqueous Solution

Goyal, Meenakshi Korean Carbon Society 2004 Carbon Letters Vol.5 No.2

Adsorption isotherms of p-nitrophenol from its aqueous solutions on two samples of activated carbon fibres and two samples of granulated activated carbons have been determined in the concentration range 40~800 mg/L (ppm). The surface of these carbons was modified by oxidation with nitric acid and oxygen gas, and by degassing the carbon surface under vacuum at temperatures of $400^{\circ}C$, $650^{\circ}C$ and $950^{\circ}C$. The oxidation of carbon enhances the amount of carbon-oxygen surface groups, while degassing decreases the amount of these surface groups. The adsorption of p-nitrophenol does not depend upon the surface area alone but appears to be influenced by the presence of oxygen groups on the carbon surface. The adsorption decreases on oxidation while the degassing of the carbon surface enhances the adsorption. The decrease in adsorption depends upon the strength of the oxidative treatment being much larger in case of the oxidation with nitric acid, while the decrease in adsorption on degassing depends upon the temperature of degassing. The results show that while the presence of acidic surface groups which are evolved as $CO_2$ on degassing suppress the adsorption of p-nitrophenol, the presence of non acidic surface groups which are evolved as CO on degassing tend to enhance the adsorption. Suitable mechanisms compatible with the results have been presented.

Knowledge, Attitude and Practice of Chewing Gutka, Areca Nut, Snuff and Tobacco Smoking Among the Young Population in the Northern India Population

Goyal, Gaurav,Bhagawati, Basavaraj T Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.11

Objective: The objective of the study was to determine the Knowledge, Attitude and Practice of chewing gutka,areca nut, snuff and tobacco smoking among the young population in the Northern India Population between the age of 15 to 22 years. Methods: The study was approved by the ethical committee. A total of 10 school and colleges located in the rural and urban areas was selected. A total of 1500 young individuals aged between 15 to 22 years were selected. A self-administered questionnaire was designed comprised of 14 closed ended questions about Knowledge, Attitude and Practice towards consumption of areca nut, gutka and tobacco smoking that were filled by the participants. Descriptive statistics were obtained and mean, standard deviation, frequency and percentages were calculated. Data was analyzed by using SPSS. Result: A total of 1050 out of 1500 students responded to the questionnaire. A total of 227 subjects agreed that they are consuming the tobacco. Out of this, 196 (86.34%) were boys and 31 (13.65%) were girls who agreed in consumption of tobacco product. Out of 196, 150 boys (76.5%) practices the habit of smoking 1 -5 times a day and 46 (23.4% ) practice the habit of chewing areca nut and gutkha 1 - 5 times a day. Out of 31 girls, 25 girls (80.6%) practices the habit of smoking 1 -5 times a day and 6 (19.4%) practice the habit of chewing areca nut and gutkha 1 - 5 times a day. Out of 740 subjects, 530 were boys and 210 girls have full knowledge of deleterious long term effects of tobacco consumption. Conclusion:The present study concluded that young population of North India lack Knowledge, Attitude and Practice regarding consumption of areca nut, gutka and tobacco smoking. Here is an urgent need to take effective steps, especially on launching community awareness programs for the school children and public to educate them about the consequences of tobacco use, and on assessing their effectiveness in curbing the problem.

A TWO-DIMENSIONAL NEUMANN EXPANSION FOR THE H-FUNCTION OF TWO VARIABLES

Goyal, S.P.,Agrawal, R.K. Department of Mathematics 1980 Kyungpook mathematical journal Vol.20 No.1