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      • Optimization of Four-bar Steering Mechanism through Artificial Immune System (AIS) Algorithm

        Yousof Ebneddin Hamidi,Morteza Saeidi Javash,Mir Mohammad Ettefagh,Farshid Abbasi Doust 제어로봇시스템학회 2012 제어로봇시스템학회 국제학술대회 논문집 Vol.2012 No.10

        In this paper, synthesis of the steering mechanism is optimized using Artificial Immune System (AIS) Algorithm for best function generation. A four-bar mechanism is employed as the Ackermann steering mechanism. For the first time the optimization in this problem is implemented with two methods. In the first method the length are selected as optimization parameter whereas in the second method precision points distribution is considered as optimization parameter. For the first method two of links have the same length in order to have a symmetric mechanism. For the precision point distribution method, five precision points are considered which one of them is in the straight line condition and the others are symmetric. Artificial Immune System (AIS) Algorithm has been used as an appropriate optimization strategy. The obtained result shows that in second method, precision points distribution as optimization parameter, the AIS algorithm can generate more accurate function. But first method, length as optimization parameter, is more practical because of its ability to satisfy all dimensional constraints.

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        The effect of melanocortin (Mc3 and Mc4) antagonists on serotonin-induced food and water intake of broiler cockerels

        Morteza Zendehdel,Farshid Hamidi,Vahab Babapour,Kasra Mokhtarpourian,Ramin Mazaheri Nezhad Fard 대한수의학회 2012 Journal of Veterinary Science Vol.13 No.3

        The current study was designed to examine the effects of intracerebroventricular injections of SHU9119 [a nonselective melanocortin receptor (McR) antagonist] and MCL0020 (a selective McR antagonist) on the serotonin-induced eating and drinking responses of broiler cockerels deprived of food for 24 h (FD24). For Experiment 1, the chickens were intracerebroventricularly injected with 2.5, 5, and 10 μg serotonin. In Experiment 2, the chickens received 2 nmol SHU9119 before being injected with 10 μg serotonin. For Experiment 3, the chickens were given 10 μg serotonin after receiving 2 nmol MCL0020, and the level of food and water intake was determined 3 h post-injection. Results of this study showed that serotonin decreased food intake but increased water intake among the FD24 broiler cockerels and that these effects occurred in a dose-dependent manner. The inhibitory effect of serotonin on food intake was significantly attenuated by pretreatment with SHU9119 and MCL0020. However, the stimulatory effect of serotonin on water intake was not altered by this pretreatment. These results suggest that serotonin hypophagia and hyperdipsia were mediated by different mechanisms in the central nervous system, and that serotonin required downstream activation of McRs to promote hypophagia but not hyperdipsia in the FD24chickens.

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