Examining Chinese Consumer Brand Attitudes: Perceived Brand Globalness vs. Localness and the Mediating Role of Quality, Prestige, and Image

Yu,Di(Di Yu),Kim,Ji Yoon(Ji Yoon Kim) 한국상품학회 2024 商品學硏究 Vol.42 No.1

The current paper investigates the impact of a brand's perceived globalness and localness on brand attitude, focusing on the mediating roles of perceived quality, brand prestige, and brand image in China. While previous studies have discussed the effect of perceived brand globalness and localness on consumers' brand attitudes and purchase intentions, there is still limited research conducted in the Chinese market. Particularly, this study differs from previous ones by examining the mediating effect of brand image in addition to perceived quality and brand prestige. The analysis reveals that perceived brand globalness and localness positively influence the brand attitude of Chinese consumers, as supported by the mediating effects of perceived quality, brand prestige, and brand image. Moreover, through mediating effect analysis, brand prestige emerges as the strongest mediator between perceived brand globalness/localness and brand attitude, indicating that Chinese consumers' attitudes toward global and local brands are primarily influenced by brand prestige. Additionally, perceived quality and brand image are found to have subsequent effects. Conversely, the primary influencing factor on Chinese consumers' attitude toward perceived brand localness is brand prestige, followed by brand image and perceived quality. This suggests that, alongside brand prestige, brand image significantly impacts Chinese consumers. These findings imply that Chinese marketing brand managers should prioritize enhancing brand prestige to meet the status and prestige pursuit of Chinese consumers. Consequently, this study is considered significant as it explores the perceived globalness and localness of brands and provides practical implications formarketingmanagers.

White-light crosslinkable milk protein bioadhesive with ultrafast gelation for first-aid wound treatment

Zhu Qinchao,Zhou Xuhao,Zhang Yanan,Ye Di,Yu Kang,Cao Wangbei,Zhang Liwen,Zheng Houwei,Sun Ziyang,Guo Chengchen,Hong Xiaoqian,Zhu Yang,Zhang Yajun,Xiao Ying,Valencak Teresa G.,Ren Tanchen,Ren Daxi 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00

Background : Post-traumatic massive hemorrhage demands immediately available first-aid supplies with reduced operation time and good surgical compliance. In-situ crosslinking gels that are flexibly adapting to the wound shape have a promising potential, but it is still hard to achieve fast gelation, on-demand adhesion, and wide feasibility at the same time. Methods : A white-light crosslinkable natural milk-derived casein hydrogel bioadhesive is presented for the first time. Benefiting from abundant tyrosine residues, casein hydrogel bioadhesive was synthesized by forming di-tyrosine bonds under white light with a ruthenium-based catalyst. We firstly optimized the concentration of proteins and initiators to achieve faster gelation and higher mechanical strength. Then, we examined the degradation, cytotoxicity, tissue adhesion, hemostasis, and wound healing ability of the casein hydrogels to study their potential to be used as bioadhesives. Result : Rapid gelation of casein hydrogel is initiated with an outdoor flashlight, a cellphone flashlight, or an endoscopy lamp, which facilitates its usage during first-aid and minimally invasive operations. The rapid gelation enables 3D printing of the casein hydrogel and excellent hemostasis even during liver hemorrhage due to section injury. The covalent binding between casein and tissue enables robust adhesion which can withstand more than 180 mmHg blood pressure. Moreover, the casein-based hydrogel can facilitate post-traumatic wound healing caused by trauma due to its biocompatibility. Conclusion : Casein-based bioadhesives developed in this study pave a way for broad and practical application in emergency wound management.

Calculative and experimental study of the CFRP tape spring

Yu-di Zuo,Guang Jin,Peng Xie 대한기계학회 2018 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.32 No.8

A tape spring is a thin-walled, straight strip of material with curved cross-section, and the current trend is towards tape springs made of carbon fibre reinforced plastic (CFRP). In this paper, performance of the CFRP tape spring was studied and its bending moment’s calculative formula during opposite-sense bending process was derivated, also, the theoretical formula’s accuracy was assessed by means of detailed, non-linear finite-element analysis. Subsequently, a CFRP tape spring was practical designed and manufactured through twiningmoulding workmanship, and some experiments were conducted to study its bending characters, verifying the validity of the theoretical analysis and finite element simulation perfectly.

A Heuristic Algorithm for Alongside Replenishment Scheduling Problem of Ship Fleet with Time Constraint

Yu Peng,He Xue-jun,Ren Ai-di 보안공학연구지원센터 2014 International Journal of Control and Automation Vol.7 No.12

The alongside replenishment scheduling problem with time constraint determining the partition of the ships, the order of replenishment and the allocation of time to the ships at the same time is analyzed. It is equivalent to a multi-stage flow shop scheduling problem with the object of maximizing the effectiveness value of ship fleet. The problem solving process is divided into three steps, and based on the analysis of the three steps, a heuristic algorithm is proposed. The algorithm firstly considers the time allocated to each ship, and then sequences the ships by heuristic rule combining greed with insertion, finally determines the ships partitioning to the port and standard side. Emulating example with different problems’ scale and time constraints shows that the proposed heuristic algorithm is superior to some other algorithms.

Preparation of 5-fluorouracil-loaded Nanoparticles and Study of Interaction with Gastric Cancer Cells

Fan, Yu-Ling,Fan, Bing-Yu,Li, Qiang,Di, Hai-Xiao,Meng, Xiang-Yu,Ling, Na Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.18

Aims: To prepare 5-fluorouracil (5-Fu) nanoparticles with higher encapsulation efficiency and drug loading, and then investigate interaction with the SGC-7901 gastric cancer cell line. Materials and Methods: Prescription was optimized by orthogonal experiments, the encapsulation efficiency and loading capacity were tested by high-performance liquid chromatography, and inhibition of proliferation by 5-Fu nanoparticles and 5-Fu given to cells for 24, 48 and 72 hours was investigated by methyl thiazolyl tetrazolium assay (MTT). In addition, 5-Fu nanoparticles were labeled by fluorescein isothiocyanate (FITC), and absorption into cells was tested by flow cytometry. Results: The optimal conditions for preparation were concentrations of 5-Fu of 5mg/ml, of $CaCl_2$ of 60 mg/ml and of chitosan of 2 mg/ml. With a stirring speed of 1200rpm, encapsulation efficiency of 5-Fu nanoparticles was $55.4{\pm}1.10%$ and loading capacity was $4.22{\pm}0.14%$; gastric cancer cells were significantly inhibited by 5-Fu nanoparticles in a time and concentration dependent manner, and compared to 5-Fu with slower drug release, in a certain concentration range, inhibition with 5-Fu nanoparticles was stronger. 5-Fu nanoparticles were absorbed by the cells in line with the concentration. Conclusions: 5-Fu nanoparticles can inhibit growth of gastric cancer cells in vitro to a greater extent than with 5-Fu with good adsorption characteristics, supporting feasibility as a carrier.

Ghost Cell Odontogenic Carcinoma Arising from Calcifying Cystic Odontogenic Tumor: A Case Report

Zhi-Yu Zhu,Yu Chen,Zhi-Gang Chu,Wei-Ping Zhang,Di Lv,Ning Geng,Ming-Zhong Yang 대한병리학회 2012 Journal of Pathology and Translational Medicine Vol.46 No.5

Ghost cell odontogenic carcinoma (GCOC) is an exceptionally rare and malignant odontogenic tumor with aggressive growth characteristics. We describe a case of GCOC which was considerably derived from a previously resected calcifying cystic odontogenic tumor (CCOT). Cellular atypia, mitotic activity, Ki-67 labeling index and matrix metalloprotease-9 positive expression rate were all increased in the currently resected specimen compared to the initial one. This is a rare case of malignant transformation of CCOT to GCOC with respect to its histopathological and immunohistochemical findings.

Effectiveness and Safety of Pemetrexed Versus Docetaxel as a Treatment for Advanced Non-small Cell Lung Cancer: a Systematic Review and Meta-analysis

Di, Bao-Shan,Wei, Kong-Ping,Tian, Jin-Hui,Xiao, Xiao-Juan,Li, Yan,Zhang, Xu-Hui,Yu, Qin,Yang, Ke-Hu,Ge, Long,Huang, Wen-Hui,Zhang, Fang-Wa Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.8

Background: Our aim was to conduct a meta-analysis to compare the efficacy and safety of pemetrexed and docetaxel for non-small cell lung cancer (NSCLC). Materials and Methods: We systematically searched the Cochrane Library, PubMed, Embase, China Biology Medicine Database for randomized controlled trials (RCTs) comparing the efficacy and toxicities of pemetrexed versus docetaxel as a treatment for advanced NSCLC. We limited the languages to English and Chinese. Two reviewers independently screened articles to identify eligible trials according to the inclusion and exclusion criteria and assessed the methodological quality of included trials, and then extracted data. The meta-analysis was performed using STATA12.0. Results: Six RCTs involving 1,414 patients were identified. We found that there was no statistically significant differences in overall response rate, survival time, progression-free survival, disease control rate, and 1-2yr survival rate (p>0.050) but it is worthy of mention that patients in the pemetrexed arms had significantly higher 3-yr survival rate (P=0.002). With regard to the grade 3 or 4 hematological toxicity, compared with docetaxel, pemetrexed led to lower rate of grade 3-4 febrile neutropenia, neutropenia, and leukocyts toxicity (p<0.001). There was no significant difference in anemia between the two arms (p=0.08). In addition, pemetrexed led to higher rate of grade 3-4 thrombocytopenia toxicity (p=0.03). As for the non-hematological toxicities, compared with docetaxel, pemetrexed group had lower rate of grade 3-4 diarrhea and alopecia. Conclusions: Pemetrexed was almost as effective as docetaxel in patients with advanced NSCLC. At the same time, pemetrexed might increase the 3-yr survival rate. As for safety, pemetrexed led to lower rate of grade 3-4 febrile neutropenia, neutropenia, leukocytes, diarrhea and alopecia toxicity. However, it was associated with a higher rate of grade 3-4 thrombocytopenia.

The application of markers (HSP70 GPC3 and GS) in liver biopsies is useful for detection of hepatocellular carcinoma

Di Tommaso, Luca,Destro, Annarita,Seok, Jae Yeon,Balladore, Emanuela,Terracciano, Luigi,Sangiovanni, Angelo,Iavarone, Massimo,Colombo, Massimo,Jang, Ja June,Yu, Eunsil,Jin, So Young,Morenghi, Emanuela Elsevier 2009 Journal of hepatology Vol.50 No.4

<P><B>Background/Aims</B></P><P>Liver biopsy for hepatocellular carcinoma (HCC) detection is largely restricted to small hepatocellular lesions, which are often morphologically challenging, requiring careful distinction between dysplastic nodules (high-grade) and well-differentiated HCC.</P><P><B>Methods</B></P><P>We investigated the diagnostic accuracy of a panel of markers (HSP70 GPC3 and GS), previously tested in resection specimens, in a series of liver biopsies of large regenerative nodules (<I>n</I>=13), low-grade dysplastic nodules (<I>n</I>=21), high-grade dysplastic nodules (<I>n</I>=50), very well-differentiated (VWD) (<I>n</I>=17), well-differentiated (WD-G1) (<I>n</I>=40) and G2-3 (<I>n</I>=35) HCC.</P><P><B>Results</B></P><P>Almost all cases of large regenerative and low-grade dysplastic nodules did not stain while high-grade dysplastic nodules showed 1 marker (22%) but never 2 or 3. For HCC detection the overall accuracy of marker combination was 60.8% (3 markers) and 78.4% (2 markers) with 100% specificity. When restricted to VWD+WD-G1 HCC the accuracy was 57% (3 markers) and 72.9% (2 markers) with 100% specificity.</P><P><B>Conclusions</B></P><P>This panel proved useful to detect well-differentiated HCC in biopsy. Two immunoreactive markers (out of 3) are recommended as the most valuable diagnostic combination for HCC detection. The diagnostic accuracy of the panel could be improved using additional markers, as suggested by studies of expression profiling in other human models.</P>

CKGS: A Way Of Compressed Key Guessing Space to Reduce Ghost Peaks

Di Li,Lang Li,Yu Ou 한국인터넷정보학회 2022 KSII Transactions on Internet and Information Syst Vol.16 No.3

Differential power analysis (DPA) is disturbed by ghost peaks. There is a phenomenon that the mean absolute difference (MAD) value of the wrong key is higher than the correct key. We propose a compressed key guessing space (CKGS) scheme to solve this problem and analyze the AES algorithm. The DPA based on this scheme is named CKGS-DPA. Unlike traditional DPA, the CKGS-DPA uses two power leakage points for a combined attack. The first power leakage point is used to determine the key candidate interval, and the second is used for the final attack. First, we study the law of MAD values distribution when the attack point is AddRoundKey and explain why this point is not suitable for DPA. According to this law, we modify the selection function to change the distribution of MAD values. Then a key-related value screening algorithm is proposed to obtain key information. Finally, we construct two key candidate intervals of size 16 and reduce the key guessing space of the SubBytes attack from 256 to 32. Simulation experimental results show that CKGS-DPA reduces the power traces demand by 25% compared with DPA. Experiments performed on the ASCAD dataset show that CKGS-DPA reduces the power traces demand by at least 41% compared with DPA.

Prognostic Factors in Adult Patients with Solid Cancers and Bone Marrow Metastases

Hung, Yu-Shin,Chou, Wen-Chi,Chen, Tai-Di,Chen, Tse-Ching,Wang, Po-Nan,Chang, Hung,Hsu, Hung-Chih,Shen, Wen-Chi,Cheng, Wei-Hong,Chen, Jen-Shi Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.1

Background: Solid cancers with bone marrow metastases are rare but lethal. This study aimed to identify clinical factors predictive of survival in adult patients with solid cancers and bone marrow metastases. Methods: A total of 83 patients were enrolled consecutively between January 1, 2000 and December 31, 2012. Bone marrow metastases were confirmed by biopsies. Patient clinical features and laboratory data were analyzed for associations. Results: The median age of the patients was 54 years (range, 23-88 years), and 58% were male. The 3 most common primary tumor locations were the stomach (32 patients, 39%), prostate (16 patients, 19%), and lungs (12 patients, 15%). The median overall survival was 49 days (range, 3-1423 days). Patients with Eastern Cooperative Oncology Group performance status 1, cancers of prostate origin, platelet counts over 50,000/ml, and undergoing antitumor therapies had a significantly better prognosis in the multivariate analysis. The median survival times were 173 and 33 days for patients with 2-3 more favorable parameters (n=24) and those with 0-1 (n=69), respectively (hazard ratio 0.30; 95% CI 0.17-0.52, p<0.001). Conclusions: Solid cancers with bone marrow metastases are dismal and incurable diseases. Understanding prognostic factors to these diseases helps medical personnel to provide appropriate treatments and better inform patients about outcomes. Antitumor therapies may improve outcomes in selected patient cohorts.