강릉시 5세 아동의 "조기 유아기 우식증" 관련 추정요인의 기술 역학적 연구

박진아,마득상,박덕영,박호원,이광수 大韓小兒齒科學會 2002 大韓小兒齒科學會誌 Vol.29 No.2

본 연구에서는 조기 유아기 우식증의 위험 인자를 규명하고 일치된 조기 유아기 우식증의 정의를 수립하는데 기초연구로서 층화집락추출법으로 선출된 강릉시 만 5세 유치원 아동들의 보호자 364명을 대상으로 이들 아동들의 조기 유아기 우식증과 관련된 형식·식이요인, 태아기나 출생기의 상태에 대한 설문조사연구를 시행한 결과 다음과 같은 결론을 얻었다. 1. 조사대상의 4분의 3이상(76.1%)의 아동이 생후 12개월 이후까지 연장된 수유를 하였으나 수면과 연관된 부적절한 수유의 빈도는 21.3%로 낮게 나타났다. 2. 대부분 보호자들(91.3%)이 이가 날 때부터 이를 닦아 주어야 한다는 사실을 알고있었음에도 불구하고, 맹출 직후 이를 닦기 시작한 경우는 35.1%에 지나지 않고 특히 2세 이후에야 이닦기를 시작하는 경우가 약 40%이상으로 조사되었다. 3. 현재 하루 칫솔질 회수가 1회 이상이 90%이상으로 매우 높게 나타났으나 5명 중 3명의 아동(61.4%)이 보호자의 도움없이 혼자 이를 닦는 것으로 나타났으며, 간식섭취 빈도는 하루 1-3회가 약 60%, 수시로 섭취하는 대상이 약 40%를 차지하여 비교적 높은 것으로 밝혀졌다(x^2-test, p<.05 or Fisher's exact test, p>.05). 4. 대부분(87%)의 첫 치과방문시기가 3세 이상인 경우로 나타나, 조기 유아기 우식증 예방에 대한 관심이 필요할 것으로 생각되었으나, 5세 아동의 예방적 치과방문 경험이 비교적 높을 것(40.2%)으로 보아 강릉지역 보호자의 구강건강에 대한 높은 의식수준을 반영한다고 볼 수 있다. 5. 보호자의 구강환경관리상태와 아동의 일일 평균 칫솔질 회수, 예방적 치과방문, 최초 치과 방문 시기와의 상관관계 및 지역별, 공사립 유치원별 및 남녀별 차이는 통계학적으로 유의하지 않았다(x^2-test, p>.05 or Fisher's exact test, p>.05). The purpose of this study was to get descriptive statistics of the contributing factors for early childhood caries and to predict the relationship of dietary, behavior factors and health status factors of the mother and child at pregnancy and after birth. 411 first caregivers of 5-year-old children in 12 kindergartens in Kangnung city were selected by stratified random cluster sampling. They were asked to fill out questionnaires and 364 of them responded The obtained results were as follow: 1. Over the three-Fourth of children used nursing bottle of had breast feeding habit beyond the age of 1 year. 2. 8.7% of respondents didn't recognize the necessity of the preventive measures immediate after eruption of primary tooth, and only 35.1% replied that they had begun tooth cleaning. 3. Over 90% of children brush the teeth more than once per day. But over half (61.4%) of them brush their teeth without parents instruction. Sixty percent of children eat between the meals as often as 1-3 time(s) a day and the remainder at any times. 4. The first time of dental visit was for most children (87%) at over 3 years, recommending the earlier dental visit. Notwithstanding the rate of routine dental visit experience was relatively high(40.2%), implicating positive parents' attitude about oral health at Kangnung area. 5. The relationships between oral health state of the parents and the variables such as the timing of the first tooth cleaning the frequency of brushing, the time of first dental visit, and the reason of first dental visit were not statistically significant. Together, there was no statistically significant difference between rural and urban area, private and public kindergarten, and boy and girl(x^2-test, p>.05 or Fisher's exact test, p>.05).

식품의 치아우식유발지수측정법 개발에 관한 연구

신승철,마득상,박덕영 단국대학교 치과대학 예방치과 1998 예방치과 세미나집 Vol.- No.12

The purpose of this study was to evaluate the reliability of the method for assessing cariogenicity of foodstuffs using pH drop by S. mutans, S. mutans was cultured with 8 ml of Tood-Hewitt broth for 7 hours. Then, this broth was centrifuged and 7 ml of supematant was removed and 1 ml of bacterial pellet was remained. Each 1 ml of 0.1%, 0.5% and 0.1% sucrose solution as the experimental groups and distilled water as a control group were mixed with these remained bacterial pellet and cultured at 37℃. The pH was measured at each 10 minutes for 2 hours. The caries potential index(CPI) was measured by calculating the width of area below pH 5.7 line. The reliability of the method was evaluated by comparing coefficients of variation of CPI. As the results, with concentration of sucrose solution between 0.1% to 1.0%, the method assessing CPI using S. mutans discriminated each CPI of solutions fairly well and was reliable.

세치제 짜는 방법에 따른 보육교사의 어린이용 세치제 사용량 조사

손정희,박일순,마득상 韓國學校保健學會 2009 韓國學校保健學會誌 Vol.22 No.1

Purpose: The purpose of this study was to examine the relationship between the toothpaste squeezing methods and the amount of toothpaste that the daycare teachers apply for the children in order to prevent the overuse of fluoride-containing toothpaste among children, and to understand their educational experiences on oral health and their awareness of the right amount of toothpaste used. Methods: The subjects in this study were 87 teachers at 16 different daycare centers in the city of Sokcho, Gangwon Province. They were interviewed to find out whether they had ever received oral health education and whether they were cognizant of the right amount of toothpaste to be used. And a transverse technique and a pea-sized squeezing technique were selected to look for connections between their toothpaste squeezing methods and the amount of toothpaste used by them. Results: 89.7 percent of the daycare teachers investigated taught to preschoolers how to do toothbrushing after they took meals and had a snack. 36.8 percent of the daycare teachers had children squeeze toothpaste on their own. The amount of toothpaste applied by the daycare teachers at a time was 0.58g. When they utilized two other squeezing methods, transverse technique and pea-sized squeezing technique, they used each 0.38g (p<0.005) and 0.38g(p=0.405) of toothpaste. Conclusion: To prevent children from being overly exposed to fluoride-containing toothpaste, daycare teachers should learn about the right amount of toothpaste to be used when oral health education is provided, and the transverse technique should be recommended to ensure the use of the proper amount of toothpaste.

전동칫솔 누가 어떻게 사용해야 하는가?

마득상(Deuk-Sang Ma) 대한치과의사협회 2017 대한치과의사협회지 Vol.55 No.2

Since early model of powered toothbrush (Broxadent) was introduced in the 1960s, the design of powered toothbrush has changed significantly. Today powered toothbrushes can be categorized as mechanical and sonic. The main patterns of movements in the modern powered toothbrushes are oscillation, reciprocation, and rotational. Powered brushes especially helpful for people who have disabilities or dexterity issue. These brushes are also highly recommended for patients who require a larger handle because these are easier to grasp. By systematic review of Cochrane group in 2014, powered toothbrushes reduced dental plaque and gingivitis more than manual toothbrushing in the short and long term. Now we can recommend powered toothbrushes to people who need to enhance self-control dental plaque removal efficacy.

강릉시 5세 아동의 조기유아우식증에 관한 연구

마득상 ( Deuk Sang Ma ),박호원 ( Ho Won Park ),정세환 ( Se Hwan Jung ),박덕영 ( Deok Young Park ) 대한구강보건학회 2004 大韓口腔保健學會誌 Vol.28 No.2

코로나 19, 인포데믹(infordemic) 그리고 근거기반치의학(evidence-based dentisty)

마득상 ( Deuk-Sang Ma ) 대한예방치과·구강보건학회 2021 大韓口腔保健學會誌 Vol.45 No.2

연구, 논문작성, 게재를 한다는 것의 의미

마득상 ( Deuk-sang Ma ) 대한예방치과·구강보건학회 2020 大韓口腔保健學會誌 Vol.44 No.3

Snail maintains metastatic potential, cancer stem-like properties, and chemoresistance in mesenchymal mouse breast cancer TUBO-P2J cells

Ma, Sun Young,Park, Jin-Hee,Jung, Hana,Ha, Sung-Min,Kim, Yeonye,Park, Dong Hyen,Lee, Deuk Hee,Lee, Sooyong,Chu, In-Ho,Jung, So Young,Kim, Il-Hwan,Choi, Il-Whan,Choi, Chang Soo,Park, Saegwang Spandidos Publications 2017 ONCOLOGY REPORTS Vol.38 No.3

<P>Snail, a zinc-finger transcriptional repressor of E-cadherin expression, is one of the key inducers of epithelial-mesenchymal transition (EMT) in epithelial cancer. In breast cancer, EMT has been associated with malignancies, including metastasis, cancer stem-like properties, and resistance to chemotherapy and radiotherapy. In this study, we analysed the role of Snail in the highly metastatic mesenchymal TUBO-P2J mouse breast cancer cells, by loss of function using short hairpin RNA. Though silencing Snail did not restore the E-cadherin expression or induce morphological changes, Snail silencing significantly ablated in vitro and in vivo metastatic potentials. In addition, Snail silencing also reduced resistance to chemotherapy drugs and cancer stem-like properties, such as CD44 expression, aldehyde dehydrogenase (ALDH) activity, colony formation, and in vivo tumour formation and growth. However, radioresistance was not decreased by silencing Snail. Collectively, this study suggested that Snail is a main regulator of the maintenance of malignancy potentials and is a good target to prevent cancer metastasis and to increase chemotherapy susceptibility.</P>

Hydroxyapatite , sodium pyrophosphate , carbamide peroxide 를 배합한 불화물배합세치제의 치은염완화 효과와 법랑질표면경도 및 명도변화에 관한 연구

마득상,박덕영,정세환,정상호,백대일,문혁수,김종배 대한구강보건학회 1998 大韓口腔保健學會誌 Vol.22 No.1

30 adult male and female subjects completed 4-week, double-blind clinical study comparing the effect on gingivitis of the dentifrice containing 0.76% sodium monofluorophosphate and 3.0% carbamide peroxide. Subjects were divided by two balanced groups according to baseline gingivitis scores. Gingivitis index was scored by Lo¨e-Silness' Gingival index. Microhardness of tooth enamel of the dentifrice containing 0.76% sodium monofluorophosphate and 3.0% carbamide peroxide and the dentifrice containing 0.38% sodium monofluorophosphate, 0.11% sodium fluoride, 0.5% hydroxyapatite, and 3.4% tetrasodium pyrophosphate was measured by microhardness tester(Shimadzu corporation Model, HMV-2000 No. 33100410, Japan) before and after 20,000 strokes with brushing machine, Brightness of tooth enamel of the dentifrice containing 0.76% sodium monofluorophosphate and 3.0% carbamide peroxide and the dentifrice containing 0,38% sodium monofluorophosphate, 0.11% sodium fluoride, 0.5% hydroxyapatite, and 3.4% tetrasodium pyrophosphate was measured by colorimeter before and after 200 strokes with brushing machine. The obtained results were as follows: 1. The dentifrice containing 0.76% sodium monofluorophosphate and 3.0% carbamide peroxide was shown to provide a statistically significant reduction in gingivitis than the control dentifrice after 4 weeks(P <0.05). 2, There was no statistical significant change in the microhardness between the dentifrice containing 0.76% sodium monofluorophosphate and 3.0% carbamide peroxide and the control dentifrice(P≥0.05). 3. There was no statistical significance of the microhardness changes between the dentifrice containing 0.38% sodium monofluorophosphate, 0.11% sodium fluoride, 0.5% hydroxyapatite, and 3.4% tetrasodium pyrophosphate and the control dentifrice(P≥0.05). 4. There was statistical significance of the brightness changes between the dentifrice containing 0.76% sodium monofluorophosphate and 3.0% carbamide peroxide and the control dentifrice(P<0.05). 5. There was statistical significance of the brightness changes between the dentifrice containing 0.38% sodium monofluorophosphate, 0.11% sodium fluoride, 0.5% hydroxyapatite, and 3.4% tetrasodium pyrophosphate and the control dentifrice(P<0.05).

식염과 Sage oil 및 수산화인회석 배합세치제의 치은염완화와 상아질지각과민완화효과에 관한 실용실험적 연구

마득상,박덕영,문혁수,백대일,김종배,배광학 대한구강보건학회 2000 大韓口腔保健學會誌 Vol.24 No.1

This double blind clinical study was done to assess the effects of the dentifrice containing 3.0% salt, 0.15% sage oil and 17% hydroxyapatite on gingivits and dentin hypersensitivity. 156 subjects were 20-25 year old females and divided into experimental and control group. Gingival index of marginal and papillary gingivae in the bimaxillary anterior teeth and dentin hypersensitiviy index were examined 3 times : baseline, after 1 and 5 months, The gingival index's scoring criteria is the same of L e and Silness' gingival index and dental hypersensitivity was scored by 4 grade which is were severe(1) to normal(4). The obtained results were as follows: 1. The dentifrice containing 3.0% salt, 0.15% sage oil and 17% hydroxyapatite was shown to provide significant reduction of gingivitis after 5 months(p<0.05). 2. The dentifrice containing 3.0% salt, 0.15% sage oil and 17% hydroxyapatite was shown to provide significant reduction of dentin hypersensitiviy 1 month(p<0.05).