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Girena Slatkeviciene,Rasa Liutkeviciene,Brigita Glebauskiene,Dalia Zaliuniene,Loresa Kriauciuniene,Giedrimantas Bernotas,Arimantas Tamasauskas 대한안과학회 2016 Korean Journal of Ophthalmology Vol.30 No.4
Purpose: Our objective was to estimate the maximum color contrast sensitivity (MCCS) thresholds in individualswith chiasma opticum damage. Methods: The pilot study tested 41 people with pituitary adenoma (PA) and 100 age- and gender-matched controls. Patients were divided into two groups according to PA size, PA ≤1 cm or PA >1 cm. A new MCCS testprogram was used for color discrimination. Results: The mean total error score (TES) of MCCS was 1.8 in the PA ≤1 cm group (standard deviation [SD], 0.38),3.5 in the PA >1 cm group (SD, 0.96), and 1.4 in the control group (SD, 0.31; p < 0.001). There was a positivecorrelation between tumor size and MCCS result (r = 0.648, p < 0.01). In the group that had PA-producinghormones, the TES was 2.5 (SD, 1.09), compared to 4.2 value in the non-functioning PA group of patients thatdid not have clinically significant hormone excess (SD, 3.16; p < 0.01). In patients with normal visual acuity (VA)or visual field MCCS, the TES was 3.3 (SD, 1.8), while that in patients with VA <0.00 was 4.6 (SD, 2.9). Conclusions: Results of the MCCS test TES were 1.9 times better in patients with PA ≤1 cm compared topatients with PA >1 cm (p < 0.01). In PA patients with normal VA, the TES was 2.35 times worse than that ofhealthy persons (p < 0.01).