RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      검색결과 좁혀 보기

      선택해제

      오늘 본 자료

      • 오늘 본 자료가 없습니다.
      더보기
      • 무료
      • 기관 내 무료
      • 유료
      • KCI등재

        A Review of Clinical and Preclinical Studies on the Therapeutic Potential of Black Seeds (Nigella sativa) in the Management of Polycystic Ovarian Syndrome (PCOS)

        Balasubramanian Rajkapoor,Maideen Naina Mohamed Pakkir,Muthusamy Sudha,Gobinath Mirunalini,Balasubramanian Rajkapoor 대한약침학회 2023 Journal of pharmacopuncture Vol.26 No.1

        Objectives: Polycystic ovary syndrome (PCOS) is a condition that occurs frequently among women of reproductive age and is a polygenic, multifactorial, endocrine, and metabolic disorder. PCOS is becoming more common as a result of risk factors such as current lifestyle, overnutrition, and stress. The use of traditional herbal medicine is higher among the global population. Hence, this review article focuses on the potential of Nigella sativa to manage women with PCOS. Methods: A literature search was carried out using databases including Medline, Google Scholar, EBSCO, Embase, and Science Direct, as well as reference lists, to identify relevant publications that support the use of N. sativa in the management of women with PCOS. Results: Several clinical and preclinical studies have demonstrated that the major bioactive constituent of black seed (N. sativa), thymoquinone, has potential for managing women with PCOS. Moreover, N. sativa may help to manage oligomenorrhea and amenorrhea in women with PCOS through its anti-inflammatory and antioxidant properties. Conclusion: N. sativa has potential for use as a herbal medicine for managing women with PCOS as an integrative medicine along with traditional and modern medicine in conjunction with calorie restriction and regular exercise.

      • KCI등재

        Antihyperglycemic Property of Tragia cannabina in Streptozotocin-Induced Diabetic Rats

        Vaiyapuri Sivajothi,Akalanka Dey,Balasundaram Jayakar,Balasubramanian Rajkapoor 한국식품영양과학회 2007 Journal of medicinal food Vol.10 No.2

        The present study was performed to investigate the efficacy of an ethanol extract of the roots of Tragiacannabina for antihyperglycemic and antioxidant effects in streptozotocin (STZ)-induced diabetic rats. Male Wistar rats wereadministered T. cannabina(250 mg/kg) orally for 21 days, and blood glucose level was measured weekly. At the end of 21days, concentrations of serum lipids such as total cholesterol, triglycerides, and high-density lipoprotein (HDL) and proteinmarkers such as total protein, albumin, globulin, and albumin:globulin ratio (A:G) were estimated. Also, levels of enzymessuch as serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), and alkalinephosphatase (ALP) were determined. Antioxidant activity of the extract was evaluated by estimating lipid peroxides (LPO),superoxide dismutase (SOD), and catalase in liver of normal control and STZ- and extract-treated rats. Histopathologicalchanges of liver and kidney were also studied in STZ-induced diabetic animals and normal controls. All these effects pro-duced by the extract were compared with glibenclamide, a standard antidiabetic drug. Oral administration of T. cannabinafor21 days resulted in a significant reduction in blood glucose level, lipid concentration, and SGOT, SGPT, ALP, and LPO lev-els accompanied by an increase in the levels of SOD and catalase in liver tissues of STZ-induced diabetic rats. Altered lev-els of protein markers also reverted back to normal. Histopathological changes of liver and kidney were returned to normal.The effects produced by the extract were comparable to that of glibenclamide. In conclusion, the T. cannabinashowed sig-nificant antihyperglycemic and antioxidant effects in STZ-induced diabetic rats.

      연관 검색어 추천

      이 검색어로 많이 본 자료

      활용도 높은 자료

      해외이동버튼