http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
You-Kyoung Han,Chang-Gi Back,Walftor bin Dumin,Jong-Han Park,Yeoung-Seuk Bae 한국농약과학회 2021 한국농약과학회 학술발표대회 논문집 Vol.2021 No.11
Fusarium wilt caused by Fusarium oxysporum and crown and foot rot caused by F. solani can result in serious economic losses on several cucurbitaceous crops, such as watermelon and cucumber in Korea. These diseases associated with soil-borne pathogens mainly induce wilting symptoms. They are extremely difficult to control and there are few effective management strategies to reduce damages. Information related to control efficacy of antifungal agents against Fusarium oxysporum and F. solani on inducing wilting symptoms on cucurbits is insufficient. In this study, 108 fungicides registered for controlling fungal disease occurring on watermelon and cucumber were tested to evaluate growth inhibition of Fusarium oxysporum and F. solani on potato dextrose agar medium. Two fungicides, cabendazim + kasukamycin and prochloraz manganese, forming large growth inhibition zone on medium showed against the two species of Fusarium. In the case of seedlings, the same results as mycelium inhibition test was shown. In further study, experimental trials will be carried out to investigate control efficacy of the promising fungicides against Fusarium wilt and crown and foot rot diseases on watermelon and cucumber in field conditions.
Bae, Jin Kyung,Kim, You-Jin,Chae, Hee-Sung,Kim, Do Yeun,Choi, Han Seok,Chin, Young-Won,Choi, Young Hee Taylor & Francis 2017 Xenobiotica Vol.47 No.5
<P>1.Drug efflux by P-glycoprotein (P-gp) is a common resistance mechanism of breast cancer cells to paclitaxel, the primary chemotherapy in breast cancer. As a means of overcoming the drug resistance-mediated failure of paclitaxel chemotherapy, the potential of Korean red ginseng extract (KRG) as an adjuvant chemotherapy has been reported only in in vitro. Therefore, we assessed whether KRG alters P-gp mediated paclitaxel efflux, and therefore paclitaxel efficacy in in vitro and vivo models.2.KRG inhibited P-gp protein expression and transcellular efflux of paclitaxel in MDCK-mdr1 cells, but KRG was not a substrate of P-gp ATPase. In female rats with mammary tumor, the combination of paclitaxel with KRG showed the greater reduction of tumor volumes, lower P-gp protein expression and higher paclitaxel distribution in tumors, and greater oral bioavailability of paclitaxel than paclitaxel alone.3.From these results, KRG increased systemic circulation of oral paclitaxel and its distribution to tumors via P-gp inhibition in rats and under the current study conditions.</P>