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        Stochastic resonance of a flexible chain crossing over a barrier

        Asfaw, Mesfin,Sung, Wokyung Editions de Physique 2010 Europhysics letters Vol.90 No.3

        <P>We study the stochastic resonance (SR) of a flexible polymer surmounting a bistable-potential barrier. Due to the flexibility that can enhance crossing rate and change chain conformations at the barrier, the SR behaviors manifest many features of the <I>bona fide</I> entropic SR, such as the power amplification peaks at optimal chain lengths and elastic constants as well as the optimal noise strengths. The pronounced peaks that emerge depending on the chain lengths and conformation states suggest novel means of manipulating biopolymers, such as efficient separation methods using undulating channels.</P>

      • KCI등재

        Do Women Benefit from Women Education Aid? Evidence from Panel Data

        Maruta Admasu Asfaw 한국국제경제학회 2023 International Economic Journal Vol.37 No.4

        Generally, the literature on aid focuses on the potential growth effects of aggregate aid. Due to the fact that donors have consistently asserted the multidimensionality of their purposes, it is necessary to conduct a much more disaggregated analysis of aid effectiveness. In this study, the effect of women education aid on 72 developing countries is examined empirically over the period 1990–2016. Using cross-country regression, this study examines the effectiveness of aid targeted at women’s education. Based on the fact that donors provide a large amount of women’s education aid to countries whose voting positions in the UN General Assembly are similar, this analysis exploits an instrumental variable. This study shows that women’s education aid has a significantly positive effect on women’s education. The results of this study are robust when different sensitivity checks are performed. The findings have significant policy implications for donor countries and international aid organizations, as they assist in identifying the most effective types of foreign aid flow to the various sectors of the recipient country’s economy.

      • Adhesion of membranes <i>via</i> receptor–ligand complexes: Domain formation, binding cooperativity, and active processes

        Weikl, Thomas R.,Asfaw<fnoteref idrefs='fn2' />, Mesfin,Krobath, Heinrich,,ż,ycki<fnoteref idrefs='fn3' />, Bartosz,Lipowsky, Reinhard Royal Society of Chemistry 2009 SOFT MATTER Vol.5 No.17

        <P>Cell membranes interact <I>via</I> anchored receptor and ligand molecules. Central questions on cell adhesion concern the binding affinity of these membrane-anchored molecules, the mechanisms leading to the receptor–ligand domains observed during adhesion, and the role of cytoskeletal and other active processes. In this review, these questions are addressed from a theoretical perspective. We focus on models in which the membranes are described as elastic sheets, and the receptors and ligands as anchored molecules. In these models, the thermal membrane roughness on the nanometre scale leads to a cooperative binding of anchored receptor and ligand molecules, since the receptor–ligand binding smoothens out the membranes and facilitates the formation of additional bonds. Patterns of receptor domains observed in Monte Carlo simulations point towards a joint role of spontaneous and active processes in cell adhesion. The interactions mediated by the receptors and ligand molecules can be characterized by effective membrane adhesion potentials that depend on the concentrations and binding energies of the molecules.</P> <P>Graphic Abstract</P><P>This review discusses theoretical models for cell adhesion in which the cell membranes are described as elastic sheets and the receptors and ligands as anchored single molecules <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=b902017a'> </P>

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        Recreational Use of Phosphodiesterase 5 Inhibitors and Its Associated Factors among Undergraduate Male Students in an Ethiopian University: A Cross-Sectional Study

        Eyob Alemayehu Gebreyohannes,Akshaya Srikanth Bhagavathula,Begashaw Melaku Gebresillassie,Yonas Getaye Tefera,Sewunet Admasu Belachew,Daniel Asfaw Erku 대한남성과학회 2016 The World Journal of Men's Health Vol.34 No.3

        Purpose: To assess the prevalence of phosphodiesterase 5 (PDE5) inhibitor use and associated factors among University of Gondar undergraduate students.Materials and Methods: An institution-based, cross-sectional study, using a survey questionnaire, was conducted from October to December 2015 to assess PDE5 inhibitor use and associated factors among male students at the University of Gondar. A Self-Esteem and Relationship questionnaire (14 items), an International Index of Erectile Function questionnaire (15 items) and a questionnaire on PDE5 inhibitor use (14 items) were included in the survey.Results: Across all respondents (age, 21.9±1.88 years), more than half (55.7%, n=233) had heard about PDE5 inhibitors, but only 23 men (5.5%) reported trying a PDE5 inhibitor drug at least once. Older students were more likely to use PDE5 inhibitors compared to younger students (adjusted odds ratio [AOR], 1.40; 95% confidence interval [CI], 1.109∼1.768). Those students who were smokers were 5.15 times more likely to use PDE5 inhibitors as compared to their non-smoking counterparts (AOR, 5.15; 95% CI, 2.096∼12.687). In addition, multivariate logistic regression showed that being in a relationship, alcohol use, greater number of cigarettes smoked per day, and more sexual partners were significantly associated with PDE5 inhibitor use.Conclusions: The prevalence of PDE5 inhibitor use among undergraduate students was 5.5%. Cigarette smoking and other substance use, older age, and greater number of sexual partners were significantly associated factors for PDE5 inhibitor use. These findings suggest that restricting access to PDE5 inhibitor drugs is essential to curtailing misuse among university students.

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