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The Distribution of Fetal Nuchal Translucency Thickness in Normal Korean Fetuses
Han Jung Yul,Kim Moon Young,Choi Kyu Hong,류현미,Chung Jin Hoon,Yang Jae Hyug,Song Mi Jin,Cho Jeong Yeon,Lee Young Ho,Park So Yeon,Choi June Seek,Kim Joo Oh,Shin Joong Sik,Ahn HyunKyong,Lim Ha Jung,Moon 대한의학회 2004 Journal of Korean medical science Vol.19 No.1
The aim of present study was to establish normative data for the distribution of nuchal translucency (NT) thickness in normal Korean fetuses. The data were collected from pregnant women with singleton pregnancies in whom fetal ultrasound was performed and the fetal NT thickness was measured between 11 and 14 weeks of gestation. Among them, a total of 2,577 fetuses with a known normal outcome were included in this study. The distribution of multiple of median (MoM) values of the NT thickness with crown-rump length (CRL) in 10-mm intervals and the 95th percentile of MoM were calculated with the linear regression method. The present study showed that NT measurements increase with increasing CRL and a false positive rate increases with increasing gestational age. Therefore, a fixed cut-off point through the first tri-mester was not appropriate and each NT measurement should be examined accord-ing to the gestational age. The present study offers normative data of the fetal NT thickness in a Korean population, which can be used as reference for screening chro-mosomal aberrations or other congenital abnormalities in the first trimester.