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      • 急ㆍ慢性 膽囊炎 患者의 膽囊內膽汁의 細菌學的 硏究

        金五經,孫基燮 충남대학교 의과대학 지역사회의학연구소 1984 충남의대잡지 Vol.11 No.1

        In general, acute and chronic cholecystitis, the pathogenesis is still not completely understood, seems to be related to four factors, obstruction, ischemia, chemical injury and bacterial invasion due to chiefly biliary stones (90-95%), and serous systemic disorders, major injuries (trauma and operation), congenital abnormalities and other bad physical conditions³). Above all the presense of organisms are responsible nat noly for the development of acute cholecystitis but also for the postoperative complications and mortality^5). About 5 per cent (about 20 per cent in the United States)^1), of surgical patient have been entered in this hospital for surgery of the biliary tract because of acute and chronic cholecystitis. In spite of that microorganisms in the biliary tract has recently not been studied in this country as well as other countries^6). The purpose of this investigation was to asses the incidence of organisms from the gallbladder bile of the patients with acute and chronic cholecystitis by utilization of standardized methods of aerobic and anaerobic cultures. Seventy eight consecutive patients with acute and chronic cholecystitis underwent cholecystectomy during the two years and nine months between january 1981 and september 1983 were studied and also correlate the presence of bateria cultured from gallbladder bile with leukocytes and several items of important liver function test. Ten consecutive with other diseases has been utilized as control group. The results are summarised as follows. 1. Of these 88 patients, 42 patents (54%) are female and 36 patients (46) are male. 2. Reference to the table reveals that 6 of the 47 gallbladder bile, or 12. 8 per cent, were cultured anaerobic organisms and 61 of the 78 gallblader bile, or 78.2 per cent were cultured aerobically 3. Of 10 gallbladder bile, control group, one had positive culture which revealed Escherichia 4. The organisms obtained from anaerobic cultures were two cases of Bacteroides fragilis 33.3%, two cases of Fusobactrium symbiosum, a Bacteroides asaccharolyticus and a Clostrium gtridiforme (16.7%), respectively. 5. The oganisms obtained from aerobic cultures were 32 cases (45. 1%) of Escherihia coli, 19 case (26.8%) of Klebsiella species, 6 cases (8.5%) of Enterobacter species, 5 cases (7. 1%) of proteus species, 3 cases (4.2%) of Citrobacter species, 2 cases (2.8%) of Salmonella typhi and the others were one of Providencia rettgeri, Aeromonas hydrophilia, Acinetobacter calcoaceticus, taphylococcus aureus, respectively. 6. The mean value of leukocytes of aerobic group was 12.461/mm³obvious difference compared to control group which was statistically significant with a p<0.05. 7. Both mean value of SGPT, SGPT and albumin of anaerobic group were P<0.05, respectively, d SGOT and albumin of aerobic group were a p<0.01, respectively, and total bilirubin was a P<0.05 those were statistically significant value.

      • 蟲垂炎의 臨床的 考察

        金五經 충남대학교 의과대학 지역사회의학연구소 1977 충남의대잡지 Vol.4 No.2

        An analysis of 410 cases of acute appendicitis was carried out which were operated at the dept. of surgery of Chungnam National University Hospital during the past 4 years and 10 months period from July 1972 to April 1977. The results were as follow: 1. Age distribution was 6 to 80 years and the most frequent incidence was in the 2nd decades as 32.2% 2. Male to female ratio was 1.1 : 1. 3. It occurred most frequently in the Summer and August. 4. The most frequent incidence of interval from onset of symptom to visit hospital was 1-2 days as 34.9%. 5. The most frequent incidence of hospital duration was 4∼6 days as 40.5%. 6. Perforated appenicitis was 105 cases (25.6%) and imperforated appendicitis was 305 cases (74.4%) on the operative findings. Complication was 4 cases (0.9%) in imperforated and 35 cases (7.5%) in perforated appendicitis. 7. Leukocytosis was 67% and the most frequent incidence was between 10,000∼15,000 per cubic mm. of blood in 34.9%. 8. The overall mortality rate was 0.5% (2 cases) in perforated and nothing in imperforated appendicitis. 9. Misdiagnostic rate was 8.1% (36 cases)

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