전침자극이 자연 발증 고혈압 흰쥐의 혈압 조절 중추에서 iNOS의 발현에 미치는 영향

황혜숙(Hwang Hyesuk),김유성(Kim Yusung),이지은(Lee Jieun),한경주(Han Kyungju),최선미(Choi Sunmi),구성태(Koo Sungtae) 한국한의학연구원 2006 한국한의학연구원논문집 Vol.12 No.3

Aims: Acupuncture has been used for the treatment of essential hypertension, but the efficacy and the mechanism of acupuncture in prevention of hypertension are still unclear. We tested the hypothesis that electroacupuncture (EA) applied to Baekhoe (GV20) changes NO/NOS system during development of hypertension in spontaneously hypertensive rats (SHR) , and thereby causes the delay of development of hypertension in SHR. Methods: The male SHR rats in the developmental stages of hypertension (7-8 weeks) were randomly divided into three groups (control group, GV20 acupuncture group, and tail acupuncture group). And the age matched Wistar Koyto Rats (WKY) were randomly divided into two groups (negative control, GV20 acupuncture group). EA treatments (10Hz, 1mA, 0.1ms) were carried out for 25 mini day for five consecutive days. The systolic blood pressure (SBP) was determined in conscious rats by the tail-cuff method using automatic BP mornitoring system. We investigated the activations of inducible NO synthase (iNOS) in nuclei of solitary tract (NTS) and rostral ventrolateral medulla (RVLM) of SHR by the western blotting method. Results: The SBP after the termination of EA stimulation applied to the GV20 was stabilized at 169.14±3.67 ㎜Hg which is lower value than that of the control group. The SBP of control group was elevated to 178.14±3.49 ㎜Hg. In addition, we evaluated NOS activity as well as iNOS protein expression of NTS and RVLM in both of SHR and WKY. The iNOS activity in NTS was significantly higher in SHR than in WKY. Furthermore, the iNOS activity of NTS showed significant decreases in EA groups compare to that of non treated SHR group. Although iNCS expression of RVLM showed non significant changes between SHR and WKY, EA significantly enhanced the iNCS expression in SHR. Our data support the hypothesis that delayed development of hypertension and altered iNOS expression of NTS and RVLM by EA stimulations in SHR rats. Conclusions: The findings demonstrate that acupuncture can change NO/NCS system in NTS and RVLM, and exert beneficial role on development of hypertension.

초등귀국학생의 학교생활 적응을 위한 동료멘토링 실행연구

황혜숙(Hwang, Hyesuk) 글로벌교육연구학회 2016 글로벌교육연구 Vol.8 No.2

본 연구는 초등 귀국학생들의 학교생활 적응을 위한 동료멘토링에 관한 실행연구로써, 귀국학생들이 학교생활에서 겪는 적응의 어려움을 파악하고 이를 해결하기 위한 방안으로 동료멘토링을 실행하여 멘토와 멘티에게 일어나는 의미 있는 변 화가 무엇인지 살펴보는 데 목적이 있다. 먼저, 귀국학생들의 학교생활 적응의 영역을 ‘교과 적응’과 ‘생활 적응’으로 구분하였고, ‘교과 적응’은 교육과정의 고난도, 교과 내용의 배경 지식의 부족, 용어 이해의 어려움으로, ‘생활 적응’은 교우관계, 교사와의 관계, 학교 문화 이해의 어려움으로 유형화 하였다. 이와 같이 귀국학생이 겪는 학교생활 적응의 어려움을 돕기 위하여 학교생활 적응의 영역에 따라 ‘교과 적응’을 돕기 위한 독서활동 동료멘토링과 ‘생활 적응’을 돕기 위한 신체활동 놀이 동료멘토링을 설계하였다. 동료멘토링은 타인규제 단계, 부분규제 단계, 자기규제 단계의 3단계로 나눠서 이루어졌고, 각 단계별로 교사와 멘토, 멘티의 주도적인 활동에 변화를 주고 각 단계에서 필요한 비계를 설정하였다. 동료멘토링 실 시 결과, 첫째, 자기효능감에 긍정적인 변화가 있었다. 둘째, 문화 간 감수성이 증진되었다. 셋째, 또래애착 관계가 형성되었다. This study is an action research of peermentoring for the adaptation to the school life in elementary school students who returned home from abroad, and aims to identify the difficulty in adapting to school life among elementary school students who returned home from abroad and by performing the peermentoring as a method to solve it, look at what the significant changes in mentor and mentee are. Peermentoring is applied to help them with the difficulty in adapting to school life. 'Reading' peermentoring for helping with 'subject adaptation' and 'physical activity' peermentoring for helping with ‘school life adaptation’ are devised depending on the area of school life adaptation. As a result of peermentoring for school life adaptation, First, between-culture sensitivity was improved. Second, self-efficacy had positive changes. Third, affectionate peer relation was formed.

침구관련 실험연구 논문 동향 분석

한경주(Han KyungJu),황혜숙(Hwang HyeSuk),김유성(Kim YuSung),이지은(Lee JiEun),정상용(Jeong SangYong),류연희(Ryu YeonHe),최선미(Choi SunMi),구성태(Koo SungTae) 한국한의학연구원 2007 한국한의학연구원논문집 Vol.13 No.2

The aim of the study was to analyze recent trends of experimental studies regarding to acupuncture and moxibustion (AM) through reviewing the 492 papers in the PubMed database in order to help researchers from overlapping study on the same theme and to spur them to investigate experimental studies on AM with understanding the current flow of that. For the analysis, we include papers in which abstract was written in English. First, we performed quantitative analysis of the experimental studies using whole of the first filtrated 492 papers. From this analysis, we could obtain the followings: "Trends of study in the most frequently appeared journals and leading authors in experimental study of AM", "The number of papers and name of journals by leading authors in experimental study of AM", "Trends of Korean papers in the most frequently appeared journals and Korean leading authors in experimental study of AM", "Classification of experimental studies related to acupuncture and moxibustion according to intervention methods or individual country" and "Assortment of experimental studies related to acupuncture and moxibustion in terms of intervention methods on leading countries". Second, we collected 72 papers considering impact factor of the journal and influential effect of the papers' result for qualitative analysis, and we divided the papers into pain related one or not, because the effect of AM on pain is major subject of AM study. The results showed that experimental studies regarding to AM still has several weakness such as limited usage of acupuncture points and inclined application of electroacupucture even though there are 361 acupuncture points in the human body and various kinds of stimulation methods using traditional needles and moxibustion. Therefore, we suggest that researchers should pay more attention to the study on basic AM research creatively and systematically through strengthening and enhancing the cooperation among colleges, research institutes and hospitals. Moreover, in order to promote the basic research of the AM, it is required that we need cross-disciplinary research as well as international collaboration research.

환경조건 및 침자극에 따른 인체 생물 광자 방출량 변화에 관한 연구

류연희(Ryu yeonhee),정상용(Jung Sangyong),황혜숙(Hwang Hyesuk),김유성(Kim Yoosung),이영섭(Lee Youngseop),양은진(Yang Eunjin),최선미(Choi Sunmi) 한국한의학연구원 2008 한국한의학연구원논문집 Vol.14 No.2

Objective: Recently biophysical research has shown very weak radiation of photons in plant, animal and human cells. Biophoton emission of the aliving system has received specific phenomena because of its scientific potential for monitoring metabolism to human body. This paper proposes a new challenge possibility of the biophoton emission in biophysiological human condition index. Method: Biophoton emission were measured with twenty one healthy volunteers. The study analyses existence for the effect of specific acupoint stimulus, exposure to the sun and low temperature in healthy volunteers. Two photomultiplier tubes which spectral range was from 300 ㎚ to 650 ㎚ was used for the detection of biophoton emission observation of possible acupuncture stimulation effect at left hand palm. Result : There was a reversion of relative emission rates from the palms affected the environment condition. Otherwise, when the acupuncture stimulation, the emission rate was not enough significantly change(p<0.05). Conclusion: In this study, biophoton emissions depend on the environment condition for all subjects. Measurments with the biophoton emission rate analysis might be much considered in future studies.