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담도 : 진행 췌장암의 젬시타빈, 5-FU, 시스플라틴 복합화학요법에 관한 2상 연구
최상봉 ( Sang Bong Choi ),이활연 ( Hwal Youn Lee ),유영진 ( Young Jin Yuh ),김성록 ( Sung Rok Kim ) 대한소화기학회 2005 대한소화기학회지 Vol.45 No.5
Background/Aims: Gemcitabine has been the standard regimen for advanced pancreatic cancer, but the effect on the response rate and survival is still disappointing, leading to many trials of combination chemotherapy. 5-FU and cisplatin were combined with g
담배 ( Nicotiana tabacum ) 세포배양에 의한 Glyphosate - 저항성 (低抗性) 개체의 재분화
최상봉(Sang Bong Choi),이광웅(Kwang Woong Lee) 한국식물학회 1987 Journal of Plant Biology Vol.30 No.1
From the single cell cultures of haploid tobacco (Nicotiana tabacum L. cv. NC 2326) glyphosate-resistant plants were regenerated. After treated with N-methyl-N`-nitro-N-nitrosoguanidine (MNNG) and then inoculated onto the LS medium supplemented with 1 mM glyphosate, the single cells survived formed colonies and calluses in 65 and 95 days after culture, respectively, and then whole plants were regenerated in 0.1 mM glyphosate-containing medium from the selected calluses. There was no difference in fresh weight and shikimate content between the selected and normal haploid calluses. When sprayed with 0.1 mM glyphosate, the shikimate contents in the regenerated and normal plants were 0.659 and 20.816 mol/g fr. wt., while that in other normal plants which were not sprayed was 0.921. In addition, the calluses induced from the regenerated plants grew without showing any retardation when treated with glyphosate. These results indicate that the secelcted calluses and regenerated plants are resistant to glyphosate.