난소 절제 쥐에서 홍국의 첨가가 혈중 지질에 미치는 영향과 혈중 콜레스테롤과 골대사 지표 및 호르몬과의 관련성

최미자,유대식,Choi Mi-Ja,Yu Tae-Shick 동아시아식생활학회 2005 동아시아식생활학회지 Vol.15 No.3

This study was performed to evaluate the effect of red-yeast-rice on blood lipids and also to investigated the relation of blood lipids, bone related hormones, and bone mineral density in overiectomized rats. Forty female rats (body weight $210\pm5$g) were divided into two groups. The rats in the first group were ovariectomized which the others received sham operation (SHAM). And then each rat group was further divided into control diet $(casein\;20\%)$ and red-yeast-rice powder supplemented $(0.1\%)$ diet group. All rats were fed on experimental diet and deionized water ad libitum for 9 weeks. Bone mineral density (BMD) and bone mineral content (BMC) were measured using PIXImus in spine and femur. Bone formation and bone resorption were measured by serum osteocalcin and urinary deoxypyridinoline (DPD) crosslinks value. Serum growth hormone, IGF-1 and calcitonin were analyzed using radioimmunoassay kits. The red-yeast-rice group had significantly lower the blood triglyceride concentration and had lower the blood total cholesterol concentration than casein group did in ovariectomized rats. And the red-yeast-rice group than casein group in ovariectomized rats. The red-yeast-rice group had significantly lower the atherogenic index than control group within the ovariectomized groups. In the experimental rats, serum total cholesterol concentration was negatively correlated with femur BMC and crosslink value. Crosslink value was negatively correlated with spine BMC and IGF-1. Osteocalcin concentration was negatively correlated with crosslink value. Growth hormone was negatively correlated with crosslink value and positively correlated with spine BMC. The findings of this study suggest that red-yeast-rices are beneficial for blood lipid in ovariectomized rats. And when considering a population-based public health approach to lowering cholesterol and bone loss, and preventing coronary heart disease and osteoporosis, the red-yeast-rice dietary supplement could provide a new approach for the maintenance of healthier cholesterol and bone.

식이 내 비타민 D 강화가 성장기 흰쥐의 골밀도에 미치는 영향

최미자,강유정,Choi Mi-Ja,Kang Yu-Jung 동아시아식생활학회 2006 동아시아식생활학회지 Vol.16 No.3

Modification of the diet during childhood and adolescence may be an effective strategy for maximizing the peak bone mass. Many supplementation studies have suggested a positive effect of the increased vitamin D intake on the bone mineral status in the elderly. However to date all studies have been conducted on old men and postmenopausal women. The aim of this study was to examine the effects of vitamin D supplementation on the bone mineral density and bone mineral content in growing rats. Twenty Sprague-Dawley female rats were divided into two groups; Control, and vitamin D supplementation. The bone mineral density(BMD) and bone mineral content(BMC) were measured using PIXImus in the spine and femur. Vitamin D supplementation did not affect the level of weight gain, mean food intake and food efficiency ratio. In addition, vitamin D supplementation had no added effect on the spine and femur BMD, and BMC. There were no significant differences in the spine BMD/weight and BMC/weight between the groups, but the spine BMD/weight and BMC/weight was 11 % higher in the vitamin D supplementation group. The femur BMD/weight and femur BMC/weight were significantly higher in the vitamin D supplementation group 9 weeks after the experiment. These results provide evidence of the beneficial effects of vitamin D supplementation on the BMD during the growth period.

타우린 첨가 식이가 흰쥐에서 혈중 지질과 간 지질 농도에 미치는 영향

최미자,서지나,Choi Mi-Ja,Seo Ji-Na 동아시아식생활학회 2006 동아시아식생활학회지 Vol.16 No.2

This study investigated the effect of dietary taurine supplementation on the plasma and liver lipid concentrations in lats fed a cholesterol free diet Twenty male-Sprague-Dawley rats(body weight $200{\pm}10g$) were divided into two groups, the control and taurine group(2% taurine supplemented in their diet). All the rats were fed on the experimental diet and deionized water for 6 weeks libitum. There were no significant differences body weight gain, food intake and the food efficiency ratio between the control and experimental groups. The rats fed the taurine diet had a significantly lower triglyceride and AI(athrogenic index) than those fed the control diet The liver total cholesterol (p<0.05) and triglyceride levels(p<0.01) were significantly lower in the rats fed the taurine diet than in those fed the control diet. These results suggest a possible role of taurine as a hypolipidemic agent in male rats fed a cholesterol free diet.

대구 지역 여고생의 체중 조절 관심도와 영양소 섭취 상태

최미자,윤순진,Choi, Mi-Ja,Yun, Soon-Jin 동아시아식생활학회 2007 동아시아식생활학회지 Vol.17 No.3

In this study, the interest of female high school students's(N=500) for weight control, as well as nutrient intake status, were analyzed. The mean age, height, and weight of the subjects were, 19.3 years, 162.2 cm and 55.4 kg respectively. Mean BMI was $21.1 kg/m^2$. According to BMI, the percentage of underweight, normal weight, overweight, and obese were 18.5 %, 60.3%, 11.3%, and 11.3% respectively. By the BMI criteria, 60.3% of the subjects were normal weight while the rate of self-recognition was 41.5%. The degree of satisfaction regarding self-body image was only 17.1% and 60.9% showed an interest in weight control. The reason for weight reduction were appearance(65.1 %) and health(24.2%). The body areas where subjects wanted to lose weight included the thighs(32.9%) and whole body(29.3%). They believed the most effective weight control strategy was exercise(81.1 %) and the strategies they used were diet(59.1 %) and exercise(40.4%). Energy intake was 1,733.4 kcal which was 86.7% of the estimated energy requirements(EER). Calcium, vitamin $B_2$, and vitamin C intakes were less than EAR by 34.4%, 40.4%, and 59.6% respectively. The intake of dietary fiber was 5.1 g only 21.1 % of the adequate intake(AI). In summary, high school females interested in weight control have significantly less calcium intake than their peers. The correlations between interest in weight control and weight and BMI were significant(p<0.001). The results of this study suggest that to achieve optimal growth, improved diets that include calcium, vitamin $B_2$, and vitamin C are recommended. High school females interested in weight control should especially be targeted for education on calcium intake.

대구지역 여중생의 영양소 및 식이섬유 섭취량

최미자 ( Mi Ja Choi ),이상희 ( Sang Hee Lee ) 대한지역사회영양학회 2008 대한지역사회영양학회 춘-추계학술대회지 Vol.2008 No.2

대구지역 성인여성의 대두식품의 기호도와 이소플라본 섭취량

최미자 ( Mi Ja Choi ),이나경 ( Na Kyung Lee ),정윤정 ( Yun Jung Jung ) 대한지역사회영양학회 2008 대한지역사회영양학회 춘-추계학술대회지 Vol.2008 No.2

대구지역 성인남성에서 식습관 및 생활습관과 혈중지질 농도

최미자(Mi-Ja Choi) 계명대학교 생활과학연구소 2012 科學論集 Vol.38 No.-

The aim of the present study was to determine the effects of food habit and lifestyle on blood lipids in men. The questionnaire included information about income, education, lifestyle factors(smoking, drinking, physical activity), and food intake. Physical activity was categorized into 5 levels according to Korean DRI. Food intake was assessed by using a semiquantitative food-frequency questionnaire in participants enrolled in a study investigating associations between food intake, blood glucose, blood pressure, and blood lipids. For each food item, participants indicated their average frequency of consumption over the past year in terms of the specified serving size. Data ware analyzed by using SAS (version 9.2; SAS Institute, Cary, NC), and statistical significance was defined as P < 0.05. Higher dairy intake was associated with lower blood glucose and triglyceride and higher HDL-cholesterol concentrations (P<0.05). Higher meat intake was associated with higher blood pressure (P<0.05). High intakes of grain is associated with high plasma glucose and triglyceride concentrations(P<0.05). No significant differences in blood lipid concentrations and blood pressure were seen between the low-and high fruit or vegetable groups. Correlation analysis showed a significant, direct association of weight and blood pressure and total cholesterol and triglyceride concentration (P<0.05), however, HDL-cholesterol concentration was inversely related to weight (P> 0.05). Dietary intakes of meat (P>0.05) was directly associated with triglyceride and LDL-cholesterol concentration. Dairy intake was inversely associated with age. Evaluation of the relation between vegetable and fruit intake and blood lipids showed no statistically significant(P>0.05). These findings suggest that a dietary pattern characterized by high intake of dairy and low of meat and grain decreases the risk of hyperlipidemia. Eating patterns are likely to vary with different socioeconomic statuses and gender. Thus, it is necessary to replicate this study in women.

대구 지역 중학생들의 식습관에 따른 영양소 섭취 상태

최미자(Choi, Mi Ja) 계명대학교 생활과학연구소 2015 科學論集 Vol.41 No.-

The aim of this study was to analyse associations between dietary habits and nutrient intake of 250 male middle school students in Daegu area. To determine energy and nutrient intake, 24-hour dietary recalls were conducted. The Statistical Analysis Systems(SAS version 9.2 Institute, Cary, NC, USA) was used for the analyses. As a result, a high proportions of students reported having three meals a day (67.6%), eating from 10 to 20 minutes on average (55.2%), and having bread or cookies for snacks (56.0%). The patterns of dietary behaviour including rice meal for breakfast, unbalanced diet, skipping breakfast, and salty or spicy diet were 84.0%, 24.0%, 14.8%, and 12.4%, respectively. However, 17.2% of the subjects reported finding no problems on their diet. With regard to regularity of food intake, 39.6% of the subjects reported having their meals at regular intervals and 40.8% replied eating proper amounts of food per serving. The subjects who had daily intake of fruits and vegetable and daily intake of milk were 51.2% and 42.4%, respectively, and those who disregarded food combinations and nutritional value were 43.6%. When compared to other groups, the mean intakes of energy, carbohydrate, zinc, and vitamin C were significantly higher in the group who had daily intakes of fruits and vegetables, and the mean calcium intake was significantly higher in the group who had daily intake of milk. Also, the mean intakes of calcium, potassium, and zinc were significantly lower in the group who daily consumed instant food. The binge eating group had a significantly higher weight and height than others, whereas the unbalanced diet group had a significantly lower weights than others. The normal diet group had a significantly higher dietary fiber intake than the binge eating and unbalanced diet groups. The mean intakes of potassium, vitamin A, and beta-carotene were significantly higher in the normal diet group than the group with irregular diet. In conclusion, students reported eating more vegetable, fruit, and milk and less instant food showed a higher intake of important nutrient for growth such as calcium, potassium, and vitamin C. These findings provide evidence that food habit plays a role in nutrient intake in middle school students.

노인기 여성의 녹차섭취습관과 영양섭취상태 및 골다공증과 건강관련지표에 관한 연구

최미자(Mi-Ja Choi),정윤정(Yun-Jung Jung) 한국차학회 2011 한국차학회지 Vol.17 No.3

대구지역 노인기 여성을 대상으로 녹차섭취습관에 따라 녹차를 규칙적으로 마시는 조사대상자를 녹차군(1잔 이상/일, 47명)으로, 전혀 마시지 않는 조사대상자를 비녹차군(52명)으로 구분하여 영양소 섭취상태와 골다공증 빈도 및 건강관련 지표와 관련성을 연구한 결과는 다음과 같다. 1. 조사대상자의 평균 연령, 체중, 신장 및 체질량지수는 녹차군과 비녹차군간에 유의적인 차이가 없었다. 2. 1일 평균 에너지 섭취량은 녹차군 비녹차군보다 유의적으로 높았으나 3대 영양소 섭취량은 녹차섭취습관에따른 유의적인 차이가 없었다. 3. 노인 여성의 평균 식이섬유, 칼슘, 칼륨, 비타민 C, 엽산 섭취량은 녹차를 규칙적으로 섭취하는 경우 유의적으로 높았고 그 외 미량영양소 섭취량은 녹차섭취 습관에 따른 유의적인 차이가 없었다. 4. 노인 여성의 수축기혈압과 이완기혈압은 녹차를 규칙적으로 섭취하는 경우 혈압이 낮은 경향을 보였으나 유의적인 차이는 없었다. 5. 혈당은 녹차군 112.2 ㎎/dL, 비녹차군 126.9 mg/dL로 녹차군이 비녹차군보다 유의적으로 낮았으나, 혈중 총 콜레스테롤 및 hemoglobin 농도는 유의적인 차이가 없었다. 6. 노인여성의 골밀도 T-score에 따라 정상, 골감소증, 골다공증으로 구분한 결과, 녹차군은 정상 29.8% 골감소증 44.7%, 골다공증 25.5%였고, 비녹차군은 정상 21.1%, 골감소증 32.7%, 골다공증 46.2%로 녹차 섭취군에서 골다공증의 빈도가 낮은 경향을 보였다. 이상의 결과에서 녹차를 규칙적으로 섭취하는 노인여성은 비녹차군 노인여성보다 식이섬유소와 칼슘 및 칼륨 섭취가 유의적으로 높았고 공복혈당은 유의적으로 낮았고, 혈압과 골다공증 유병율은 낮은 경향이었으나 유의적인 차이는 없었다. The purpose of this study was to investigate nutrients intake and osteoporosis prevalence and health-related markers (% body fat, SBP, DBP, hemoglobin, total cholesterol, fasting blood glucose) by green tea drinking habit in older women in Daegu. The older women (mean age 72.07±4.19 years) were asked separate questions about green tea drinking was categorized as green tea drinkers (regularly 1-2 cups over/day; Greentea group) or non-green tea drinkers (Non-greentea group) on the basis of self-report. Dietary nutrients intake data were obtained through the 24hours recall method. Milk intake and refusal food frequency were significantly differences between Greentea group and Non-greentea group. The mean intakes of energy, dietary fiber, calcium, phosphorus, potassium, vitamin C, folate were significantly higher in the Greentea group than in the Non-greentea group. Body fat, SBP, DBP, hemoglobin and total cholesterol concentration were not significantly differences between Greentea group and Non-greentea group. But fasting blood glucose was lower in the greentea group than in the Non-greentea group. The prevalence of osteoporosis and osteopenia according to T-scores were not significantly differences between Greentea group and Non-greentea group.

대구지역 여자 중학교 운동선수의 영양소 섭취와 식습관

최미자 ( Mi Ja Choi ),최수영 ( Su Young Choi ) 한국운동영양학회 2007 Physical Activity and Nutrition (Phys Act Nutr) Vol.11 No.2