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임기무(K. M. Lim),민병구(B. G. Min),고형종(H. J. Ko),심은보(E. B. Shim) 한국정밀공학회 2004 한국정밀공학회 학술발표대회 논문집 Vol.2004 No.10월
The object of this study is to develop a model of the cardiovascular system capable of simulating the short-term transient and steady-state hemodynamic responses such as hypotention and disequilibrium syndrome during hemodialysis or hemofiltration. The model consists of a closed loop 12 lumped-parameter representation of the cardiovascular circulation connected to set-point models of the arterial and cardiopulmonary baroreflexes and 3 compartmental body fluid and solute kinetic model. The hemodialysis model includes the dynamics of sodium, urea, and potassium in the intracellular and extracellular pools, fluid balance equations for the intracellular, interstitial, and plasma volumes. We have presented the results of many different simulations performed by changing a few model parameters with respect to their basal values.
이중박동형 좌심실보조장치를 부착한 인체의 혈류 순환 모델
김유석(Y. S. Kim),임기무(K. M. Lim),김문수(M. S. Kim),심은보(E. B. Shim),최성욱(S. W. Choi) 대한기계학회 2009 대한기계학회 춘추학술대회 Vol.2009 No.11
To develop VAD(Ventricular Assist Device) we prevent a numerical blood circulation model. Newly developed D-pulsatile VAD and, unlike conventional artificial heart blood flow can be inhaled by active, reducing the load of the heart in vivo to increase the amount of blood circulation can provide a variety of operating mode. In using VAD, it will change hemodynamic resistance at intra blood circulation by increasing blood pressure and blood circulation value quantities. A blood circulation or blood pressure changes depending on the model simulate characteristics of the public human condition. VAD numerical model is made to actual performance measurement for Twin Pulsatile Life Support System(T-PLS) that was developed by Kangwon National University Artificial Organ Center. We predicted and compared various operating condition using integrated model of VAD, Heart and circulatory system for increase of the blood circulation and minimize the load on the heart.